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21 Cards in this Set
- Front
- Back
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Howell-Jolly Bodies
-RBC's nucleus is supposed to be eaten by macrophage, but sometimes pieces are missed (will eventually be found by another macrophage) |
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Heinz bodies -oxidized hemoglobin -easily seen w/ Vital Stain (new methylene blue) -very sensitive to environment
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-young, larger, bluish (due to ribosomes- will lose) -normal: very low numbers -sick/anemic: high numbers
-seen w/ Romanowski's stain
*not seen in horse (RBC width dist. instead) |
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*only seen with Vital Stain
-probably same as chromasia -aggregated ribosomes/ER
*no reticulocytes in horses! |
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Nucleated RBCs
-normal in small numbers |
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Basophilic stippling -due to ribosomes; deficiency of ribosome-metabolizing enzyme (pyrimidine 5' nucleotidase) -lead poisoning in dog |
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Anisocytosis |
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Poikilocytosis |
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macrocytosis |
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Creantion
-processing issue; slide not allowed to dry |
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Schistocytes
-coagulation issue |
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Spherocytes
-immune-mediated hemolytic anemia; macrophage takes a chomp trying to get antibodies |
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Acanthocytes
-pseudopodia-like thing -sign of RENAL disease; changes in outer lipid layer |
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Target cells
-hemoglobin trapped in center due to lipid membrane change |
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Stomatocytes
-change in inner lipid layer of membrane |
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Dacryocytes
-lost flexibility, can't maintain shape -uncommon in animals (seen w/ bone marrow dz in humans) |
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Hypochromasia
-iron deficiency -smaller cells because are continually dividing |
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Rouleaux
-w/ saline, will disperse! If dispersed, not agglutination |
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Agglutination
-antibodies react to self antigens |
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Sickle cells
-common in deer; change in oxygen retention of cells |
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Hemoglobin polymerization -seen on normal smears, no known significance |