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21 Cards in this Set

  • Front
  • Back

Howell-Jolly Bodies



-RBC's nucleus is supposed to be eaten by macrophage, but sometimes pieces are missed (will eventually be found by another macrophage)

Heinz bodies


-oxidized hemoglobin


-easily seen w/ Vital Stain (new methylene blue)


-very sensitive to environment


-young, larger, bluish (due to ribosomes- will lose)


-normal: very low numbers


-sick/anemic: high numbers



-seen w/ Romanowski's stain



*not seen in horse (RBC width dist. instead)

*only seen with Vital Stain



-probably same as chromasia


-aggregated ribosomes/ER



*no reticulocytes in horses!

Nucleated RBCs



-normal in small numbers

Basophilic stippling


-due to ribosomes; deficiency of ribosome-metabolizing enzyme (pyrimidine 5' nucleotidase)


-lead poisoning in dog

Anisocytosis

Poikilocytosis

macrocytosis

Creantion



-processing issue; slide not allowed to dry

Schistocytes



-coagulation issue

Spherocytes



-immune-mediated hemolytic anemia;


macrophage takes a chomp trying to get


antibodies

Acanthocytes



-pseudopodia-like thing


-sign of RENAL disease; changes in outer lipid layer

Target cells



-hemoglobin trapped in center due to lipid membrane change

Stomatocytes



-change in inner lipid layer of membrane

Dacryocytes



-lost flexibility, can't maintain shape


-uncommon in animals (seen w/ bone marrow dz in humans)

Hypochromasia



-iron deficiency


-smaller cells because are continually dividing

Rouleaux



-w/ saline, will disperse! If dispersed, not agglutination

Agglutination



-antibodies react to self antigens

Sickle cells



-common in deer; change in oxygen retention of cells

Hemoglobin polymerization


-seen on normal smears, no known significance