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26 Cards in this Set

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  • Back
folliculitis
minor infection of the hair follicle
usually caused by staph aureus and some times pseudomonas aeruginosa from hot tubs
Acne vulgaris
involves inflammation of hair follicles and associated sebaceous gland
*caused by propionibacterium acnes, the predominant anaerobe of the skin
Furuncles
small staph abscess that develops in region of hair follicle. maybe solitary, multiple, and may be recurrent
carbuncle
furuncle spreads to dermis and subcutaneous tissue --> extensive multiloculated abscess.
genearally caused by dermatopphytes and candida
impetigo or pyoderma
starts as small vesicle that spreads and dries to a honey colored crust

generally caused by S pyogenes but sometimes due to S aureus
Bullous impetigo
large serum filled bullae (blisters) with skin layers at site of infection
common in children usually by S aureus
staphylococcal scalded skin syndrome
due to toxins, exfoliation causes splitting of epidermis between stratum spinosum and stratum granulosum
obviously caused by staph
erysipelas
rapidly spreading infection of deep layers of dermis. caused by strep pyogenes
Cellulitis
will be warm
accute inflamation of subcutaneous CT w/o predisposing trauma usually caused by S. areus and S. pyogenes
with trauma usually caused by enterobacteriaceae and obligate anaerobes can be involved
eikenella corrodens
usually found in human bites
pasteurella multocida
usually found in animal bites, especially cat bites
aeromonas hydrophila
usually found in fresh water injuries
vibrio vulnificus
usually found in saltwater injuries
necrotizing fasciitis
deep infection of subcutaneous tissue results in destruction of fascia and fat. may spare the skin AKA flesh eating bacteia of Group A strep. and sometimes by clostridium prefringes
granulomatous skin lesions
caused by either mycobacterium ulcerans, tuberculosis, marinum, disseminated fungal infections, sporothrix
how do you treat toxic shock syndrome
generally caused by staph aureus

saline, cefazolin and gentamicin

after id in hospital was staph continue with cefazolin. after discharge continued with dicloxacillin
ergosterols
make up the cell membrane of fungi, so it is the target of many antifungals.
how do azoles work
inhibit ergosterol synthesis in fungi
how do polyenes work
bind to ergosterol in fungi to increase permiability
amphotericin B
main anti-fungal therapy but is very toxic so fluconazole or itraconazole used
what makes up cell wall of fungi
mannan, glucan, and chitin

mannan- is major Ag of fungi
glucans is a polymer
chitin is long unbranched chains of glcNac
caspofugin
antifungal that blocks glucan synthesis
conidia
asexual reproductive elements of fungi
blastoconidia
buds of yeast
mycelium
intertwined mass of hyphae
dermatophytes
mostfungi infections are non-communicable between humans except for dermatophytes.

Ab's may develope, but serve no protective role, cell mediated immunity important