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7 Cards in this Set

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  • Back

Ionization


Results in the formation of a positive atom and a dislodged negative electron.

Free radical formation

An uncharged or neutral atom or molecule that exists with a single, unpaired electron in its outer shell.



Highly reactive and unstable


Water is broken into free radicals by x-ray energy


Ionization of water is the most common mechanism of damage in humans



Free radicals combine with ordinary molecules to form a toxin (ie. Hydrogen peroxide H2O2.. capable of producing widespread cellular changes)

Radiation injury sequence

Latent period- the time between exposure and the appearance of observable clinical signs



Period of injury follows: cellular changes



Recovery period: some cells can repair the damage



Cumulative effects: repeated radiation, additive damage

Exposure

FMX- 3-7 Days of background radiation


PANO = 4 BW



First sign of overexposure: Erythema

Radiation Effect on Cells

The response of a cell to radiation exposure determined by:



Mitotic activity: cells that divide frequently


Cell differentiation: cells that are immature


Cell metabolism: cells that have higher metabolism

**Cell Sensitivity to Radiation

HIGH: reproductive tissue, lymphoid system, bone marrow, intestines, mucous membranes



MEDIUM: fine vasculature, growing cartilage & bone, salivary glands, lungs, liver and kidney



LOW: nerve tissue, skeletal muscle, heart, mature bone, optic lense

Radiation Measurements

Air = Roengten = Couloumb/kg



Dose = Rad = Gray (Gy)



Dose equivalent = Rem = Sievert (Sv)