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75 Cards in this Set
- Front
- Back
What is the source of the majority of annual exposure?
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background radiation
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example of background radiation
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cosmic rays
terestrial internal radiation- found in our bodies radon |
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examples of EM radiation
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ultrasound
radio waves microwaves visible light xrays |
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Inverse square law
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double the distance = a quarter the cGry
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xray, gamma, electrons quality factor
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1
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thermal neutrons quality factor
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5
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heavy particles quality factor
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10
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quality factor
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expresses the ability of radiation to do damage
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Result of Compton
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photon strikes loosley bound outer shell electron and transfers its energy to the electron = electron gets knocked out ( photon goes off in predicted angle)
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energies for Compton
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150-900 keV
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compton scatter is most likely at
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1-5MeV
the higher the energy the smaller the probability |
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example of Compton
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port films
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Photoelectric
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involves inner shell electron...
photon is absorbed by the atomic electron the higher the energy the greater the probability |
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Auger electron =
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characteristic x-ray ejecting electron
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Delta ray =
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when an electron that has been kicked out has enough energy to kick out another electron
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Outcome of pair production
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photon strikes nucleus, knocks out electron and positron ( .511MeV)
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pair production is only important at energies above
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10MeV
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pair productions correlation to atomic number
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probability increases with atomic number
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photoelectric effect varies directly with the
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Z^3
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Brehms
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high speed electron accelerates by the nucleus ( breaking radiation )
- inefficient |
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Brehms = ____ of the incident electron
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1/3
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the conversion of mass into energy
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annihilation radiation
(2nd part of pair production- produces 2 photon) |
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Compton scattering occurs at energies
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less than 10 keV
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Another name for Coherent scattering
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Rayleigh
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Coherent probable
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in high atomic number materials
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Coherent no effect on
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radiation therapy
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coherent: no energy is ________ or ___________
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lost or absorbed
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xray interactions important to xray
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coherent and Compton
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neutrons and photon attempt to stabilize
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photodisentegration
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what is ionization
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neutral atom acquires positive or negative charge
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direct ionization
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charged particles collide with electrons (DIRECTLY) kicking out the electron
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indirect ionization
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NEUTRONS OR PHOTONS, liberate directly ionizing particles from matter
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excitation
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the incident particle doesn't have enough energy to kick an electron out just enough to SHAKE IT UP a bit
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Examples of radiatiosensitive cells
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basal cells of the skin, intestinal crypt cells, and reproductive germ cells
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most radio sensitive blood cell in the body
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lymphocytes
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factors that effect tissue response
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total dose
radiation type cell sensitivity volume of tissue irradiated protraction fractionation |
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examples of radiosensitive
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brain, muscle, and nerve
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Law of Bergonie and Tribondeau
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cells that are rapidly dividing, actively dividing, undifferentiated, and have a long mitotic future
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LET
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linear energy transfer
- low LET = diagnostics xray, more penetrating - high LET = alpha particles |
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As LET increases, radiations ability to produce damage ________
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decreases
RBE |
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RBE
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relative biologic effectiveness
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OER
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oxygen enhancement ratio
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Hematopoietic syndrome dose
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100-1000cGy
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one time lethal dose
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- prodromal
- manifest - latent 300-500cGy death w/in 30-60 days |
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Prodromal symptoms
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N/V, fatigue, hypertension, diarrhea
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Manifest syndromes
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Hematopoietic, GI, CNS
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dose that could be lethal to a embryo/fetus in the 1st trimester
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.05Gy
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most sensitive trimester for embryo
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1st
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GI syndrome doses
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1000-10,000 cGy
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CNS syndrome doses
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doses greater than 10,000cGy
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acute radiation syndrome AKA
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radiation sickness
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radiation sickness AKA
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radiation toxicity
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4 R's of radiobiology
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Reoxygenation
Repopulation Redistribution/Re assortment Repair |
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Whole body tolerance dose =
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5 rem/ yr
.05 Sv |
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1rem =
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.01 Sv
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1Sv=
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100 rem
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1 rad=
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.01 Gy
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1 Gy =
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100 rads = 100 cGy
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1R =
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2.58 x 10 ^ -4 C/kg
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1Ci=
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3.7 x 10 ^10 Bq
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1Bq=
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2.7 x 10 ^- 11 Ci
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Linear non- threshold
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stochastic
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Linear threshold
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non stochastic
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what is the dose response curve choice for rad. protection
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linear non- threshold ( no safe dose )
all or nothing effects |
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leukemia is ___________
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nonthreshold (stochastic) linear response
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examples of hyper fractionation
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BID and TID
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LET determines
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QF
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low LET
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indirect
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high LET
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direct
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high LET causes
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more damage and more double strand breaks
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stochastic are _______________ effects
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probabilistic
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there is no such thing as a ___________________
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safe gonadal dose
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wk 15 of trimester
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beginning of 2nd trimester
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wk 28 of trimester
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beginning of 3rd trimester
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10 day rule
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xray exams should be schedules w/in 10 days of onset of last LMP
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