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17 Cards in this Set
- Front
- Back
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What is virus causes Rabies?
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Rhabdovirus
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T/F
Antigenic variations are associated with pathogenicity, not host specificity |
True
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Who does rabies affect?
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all warm-blooded animals
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who is rabies more common in?
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young - no breed or sex predilections
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When is rabies more common?
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fall
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how is rabies transmitted
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bite wounds
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what cycle maintains rabies?
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salivation cycle - skunks, bats, raccoons, foxes, barn cats (unvacc)
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pathogenesis of rabies
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1. after inoculation - virus replicates in m
2. incubation period - 2w - months 3. travels via axons to peripheral nn to grey matter of BS and SC 4. rapid spread thru rest of CNS and SNS 5. travels back along nerves to organs 6. virus binds nicotinic ACH receptors? |
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is viremia/hematogenous spread a factor for rabies?
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no
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are the CS of rabies all similar?
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no highly variable
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3 forms of rabies - which are most common
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dumb/brainstem form -most common
furious/cerebral form paralytic/spinal cord form |
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CS of dumb/brainstem form
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dumb - depression, ataxia, drooling, pharyngela paralysis, ADR
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CS of furious/cerebral form
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convulsions, aggressiveness, photophobia, hydrophobia, hyperesthesia
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CS of paralytic/spinal cord from
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ascending paralysis
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Progression of Rabies
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rapid once CS develop, 5-10d until death
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Dx
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post-mortem - exam of brain
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Prevention
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vaccinate
upon exposure - revacc previously vacc horses and iso upon exposure - unvacc horse - isolate/euth |
