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20 Cards in this Set

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Best marker for MI

Troponin (includes cTnI and cTnT)

Complex regulatory proteins considered the "gold standard" in diagnosis of acute coronary syndrome

Next best marker for MI

CKMB

CHF is the most common cause of heart failure. It is best monitored by (4 markers)

BNP, troponins, CRP and homocysteine

Mamunie's speech, and best marker for MI are two of these

Most important test for PE (pulmonary embolism)

D-dimer

quarters, nickels and ....???? in my chest

Friedewald calculation

Chol - HDL - (TG/5)

A measure of LDL

EAG (estimated average glucose)

(28.7 x HbA1c value) - 46.7

Rochelle's presentation includes HbA1c

Measurement of glucose

Glucose oxidase and hexokinase

Methods to diagnose diabetes mellitus in patients with possible symptoms.

•1.HbA1c ≥6.5% using NGSP-certified method




•2.Diabetes symptoms + random glucose level of ≥200 mg/dL




•3. A fasting plasma glucose of ≥126 mg/dL

Measurement of HbA1c

Affinity chromatography is preferred method of measurement.

CA 15-3 vs CA 125

CA 15-3: Breast Cancer




CA 125: Ovarian Cancer

Tumor markers mostly in women

CEA vs alpha-fetoprotein

CEA: Colorectal cancer, lung, breast and GI tumors




Alpha-fetoprotein: Hepatocellular carcinoma & germ cell tumors

tumor markers

Most specific tumor marker for prostate cancer

PSA (prostate specific antigen)

Hep A vs Hep C

Hep A: Infectious hepatitis, most common




Hep C: Non-A, Non-B hep at least 6 genotypes

Opposite forms

Attributes of Hep B

HBsAg = current infection




HBcAb and HBsAb = natural, past exposure




HBsAg = chronic hepatitis




HBsAb w/o HBsAg or HBcAb = vaccination





Surface antibody (HBsAb) alone is the antibody due to vaccination

Prehepatic jaundice

Increased indirect bilirubin, plus high AST and ALT

Reye's Syndrome

Associated with ingestion of aspirin during viral syndrome

Stop pill popping!!

Bilirubin methods

Primarily Malloy and Evelyn or






Jendrassik-Grof methods (diazotized sulfanilic acid)

Respiratory vs metabolic acidosis

Respiratory: Decrease pH and Increased pCO2




Metabolic: Decrease pH and decrease HCO3-

Respiration = opposite




Metabolic = moves together

Normal ratio bicarbonate to carbonic acid

20:1

Oxyhemoglobin

Hemoglobin with O2 reversibly bound.