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120 Cards in this Set

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Definition:

child at fertilization to 8 weeks
Embryo
Definition:

child at 8 weeks to delivery
Fetus
Definition:

Softening and cyanosis of the cervix at or after 4 weeks
Goodell's sign
Definition:

softening of the uterus (after 6 weeks)
Ladin's sign
Definition:

first trimester
fertilization to 12 weeks
Definition:

second trimester
12 weeks to 24 weeks
Definition:

third trimester
24 weeks to delivery
Definition:

child delivery less then 24 weeks
Priviable
Definition:

Quickening
Patient's initial presentation of fetal movement
what are the changes in CO, HR, SV, TPR and BP during pregnancy?
Inc CO, HR, SV

Dec TPR,

Dec BP (returns to nml >24 weeks)
(4) Respiratory changes during pregnancy
Inc Tidal volume,

Inc PaO2 and PAO2,

Dec lung capacity,

Mild Respiratory Alkalosis
(3) GI changes during pregnancy
Inc vomiting,

Dec motility (constipation),

Prolonged gastric emptying (GERD)
(4) Renal changes during pregnancy
Inc kidney size,

Inc GFR (by 50%) leading to...

Dec BUN and Creatinine by 25%,

Inc Renin, Aldosterone and Na absorption
(balanced by Inc GFR)
(4) Blood changes during pregnancy
Inc plasma volume (50%),

Inc RBC (20%),

both percents lead to Dec Hct,
possibly causing Iron deficiency anemia,

Inc Fibrinogen and factors VII - X leading to...
Inc Thromboembolism
what hormones are maintained by the placenta in pregnancy?
(4)
Estrogen,

hCG,

hPL,

Progesterone (after initial maintenance from corpus luteum)
what causes increased Thyroid Binding Globulin?

how does this affect T3 and T4?
Inc estrogen

T3 and T4 inc binding to TBG leading to low serum levels of free T3 and T4
what is the cause of gestational diabetes?

how?
hPL

it is an insulin antagoinist
(inc diabetic effect and leading to inc insulin and protein synthesis)
what is the adequate amount of nutrition needed in pregnancy?

breast feeding?
Pregnancy: 300 kcal/day

Breast feeding: 500 kcal/day
how often should prenatal visits be?
every 4 weeks until week 28

week 28 - 36: every 2 weeks,

36 to term: every week
when is genetic screening done?
what are the (3) main tests?
during second trimester
(usu 15 - 20 weeks)

MSAFP,

b-hCG,

Estriol
which germ cell ovarian tumor has a different treatment method then the others?

what is the Tx?
Dysgerminoma

Tx:
Radiation
what is tested in pregnancy b/t 27 and 29 weeks?
(3)
Glucose Loading Test (for gestational diabetes),

Hematocrit (for iron levels),

Glucose Tolerance Test if GLT is positive
how is the Glucose Loading Test performed?

(2)
give 50g oral glucose and check in one hour

if > 140 mg/dL, then do GTT
How is a Glucose Tolerance Test performed?

What are the blood glucose values for fasting, one, two and three hour intervals?
Fasting glucose:

give 100 g oral glucose and test at 1, 2 and 3 hours

Gestational Diabetes =
Fasting glucose > 105 mg/dL
or
any two values over 180, 155 or 140 respectively
what can dehydration lead to later in pregnancy?
Braxton-Hicks contractions
what causes edema of lower extremities, feet and ankles, and hemorrhoids in pregnancy?

Tx?
Compression of IVC and pelvic veins

Tx:
elevating feet
what is the best test for fetal lung maturity?

normal levels?
Lecithin/Sphingomyelin ratio

nml > 2
describe a positive Non-Stress Test
2 increases in FHR in 20 min that are >15 beats above nml and for >15 seconds
describe a positive Oxytocin Challenge Test
3 contractions in 10 minutes
(5)* categories of the Biophysical Profiles
Test the Baby MAN!:

Fetal Tone,
Fetal Breathing,
Fetal Movement,
Amniotic Fluid volume,
NST

(zero or 2 points each; nml is 8 - 10)
Test the Baby MAN!
Definition:

multiple gestation w/ at least one IUP and at least one ectopic
Heterotrophic Pregnancy
at what b-hCG levels should you detect an IUP on vaginal US?
IUP should be seen on US w/ b-hCG of
1500 – 2000 mIU/mL
at what b-hCG levels should you detect a fetal heartbeat w/ trans-abdominal US?
Fetal heartbeat should be seen w/ b-hCG > 5000 mIU/mL
Tx for Ruptured Ectopic
Exploratory Lap

(and maintain fluid levels)
what hormone best resembles b-hCG?

how?
LH

they also have similar beta units
(in addition to similar alpha)
what is the criteria to use Methotrexate for an ectopic?
(2)
ectopic must be < 3.5 cm,

w/o heartbeat
what is the progesterone level in a nonviable intra- or extra-uterine pregnency?
< 5 ng/mL
what is the progesterone level in 98% of intrauterine pregnancies?
> 25 ng/mL
what does G5P2124 indicate?
Twins
Definition:

Spontaneous abortion time
pregnancy ending < 20 weeks
Type of Abortion:

any IU bleeding < 20 weeks w/o dilation or expulsion of POC
Threatened abortion
Type of Abortion:

death of embryo of fetus < 20 weeks w/ complete retention of POC (usu leads to complete SAB)
Missed abortion
Type of Abortion:

no expulsion of POC, but bleeding and dilation of cervix such that viability is unlikely
Inevitable abortion
(2) ways an incomplete abortion can be taken to completion in first trimester
D&C

Prostaglandins (Misoprotol)
causes of abortion in second trimester
(4)
Congenital abnormalities

cervical / uterine abnormalities,

trauma,

systemic Dz or infection
(3) ways an incomplete abortion can be taken to completion in second trimester
D&E,

Prostaglandins (Misoprostol),

Oxytocin at high doses
Definition:

Painless dilation leading to infection, Preterm Premature Rupture of Membranes (PPROM) or PTL
Incomplete cervix
what should be done if patient is in first trimester and has a history of incomplete cervix?

when?
Cerclage

12 - 14 weeks
(3) tests to verify if patient has ruptured membranes
Pool - collection of fluid in vagina

Nitrazine - turns blue (alkaline)

Ferning
Definition:

Rupture of membranes > 1 hour before onset of labor
Premature Rupture of Membranes
(PROM)
(5) parts of a Bishop score
Dilation,

Effacement,

Station,

Cervical consistency,

Cervical position
Bishop score points zero - 3 for:

Dilation
zero: Closed

1 point: 1 - 2

2 points: 3 - 4

3 points: > 5
Bishop score points zero - 3 for:

Effacement
zero: 0 - 30%

1 point: 40 - 50%

2 points: 60 - 70%

3 points: > 80%
Bishop score points zero - 3 for:

Station
zero: -3

1 point: -2

2 points: -1 to zero

3 points: +1 - +3
Bishop score points zero - 3 for:

Cervical consistency
zero: Firm

1 point: Medium

2 points: Soft

3 points: (none)
Bishop score points zero - 3 for:

Cervical position
zero: Posterior

1 point: Mid

2 points: Anterior

3 points: (none)
Definition:

Lengthening (thinning) of the cervix
Effacement
Definition:

relationship of fetal occiput to maternal pelvis
Fetal Position
(4) ways to Induce labor
Pitocin,

Prostaglandins (Cervadil or Misoprostol),

Mechanical dilation of cervix,

Rupture of membranes (Amniotomy)
MC 4 steps to Augment and monitor labor progress
water broke?
if not -> Amniotomy

change?
if not -> IUPC

change?
if not -> Pitocin

change?
if not -> C-section
what does an IUPC measure with respect to contractions?
(2)
1. Time of contraction

2. Strength of contractions
Name the (6)* movements of labor in order and what each means
Engagement - biparietal diameter (largest) part of head enters pelvis,
Flexion - smallest diameter of head enters,
Descent - head completely into pelvis,
Internal rotation - from OT to OA or OP,
Extension - vertex passes beyond pubic synthesis; crowning occurs
External rotation - after delivery of the head as the head rotates to face forward
Every Fetus Delivers Involving Excited Externs
(3) P's of the Active Phase that may cause problems in delivery
Power
(strength of contractions),

Passenger
(size and position of infant),

Pelvis
(shape)
(5) steps of Tx in patient w/ Non-reassuring fetal status
1. Give mother oxygen mask

2. turn her to Left side to decrease IVC compression

3. D/C Pitocin

4. if due to Hypertonus (long contraction) or Tachysystole (>5 contractions in 10 min), give Terbutaline to relax uterus

5. If 1 – 4 does not work, C-section patient
Dx:

Painless vaginal bleeding in the third trimester

Tx for perterm patient (<36 weeks)?
(3)

Tx for term patient?
Placenta previa

Tx for Preterm:
1. Monitor in hospital
2. Transfusion PRN
3. Tocolytic to prolong until 36 weeks

Tx for Term:
C-section
Dx:

Vaginal bleeding, painful contractions, firm and tender uterus

Tx?
Placental Abruption


Tx - Delivery
(by C-section if mother or baby is unstable)
Dx:

sudden onset of intense abdominal pain assoc w/ pregnancy

Tx?
Uterine rupture


Tx - immediate laparotomy
Dx:

Vaginal bleeding and sinusoidal FHR pattern

MCC?

Tx?
Fetal Vessel Rupture

MCC - Velamentous cord insertion

Tx - emergency C-section
Dx:

contractions and changes in cervix at < 37 weeks gestation
Preterm Labor
The only Tocolytic approved by the FDA

MOA?
Ritrodrine


MOA: Beta-agonist
Tocolytic that acts as a calcium antagonist
Magnesium sulfate
what is the test to determine if patient is near a Magnesium sulfate toxicity?
check DTRs continuously...they are depressed less then the toxic level of 10 mg/dL
what Calcium channel blocker is used as a Tocolytic?
Nifedipine
what NSAID is used as a Tocolytic?
Indomethacin
MC concern w/ PROM?
Chorioamnionitis
when is it common to see maternal hypotension?

what can it cause in child?

what is Tx for maternal hypotension?
After epidural

causes - Fetal bradycardia

Tx - IV hydration and Ephedrine
Tx for fetal bradycardia lasting for longer then 4 - 5 minutes?
C-section
Monozygotic Twins:

separation before the differentiation of trophoblasts
Dichorionic-Diamnionic
Monozygotic Twins:

separation after trophoblast differentiation and before amnion formation
Monochorionic-Diamnionic
what type of twins can develop Twin-to-Twin Transfusion Syndrome?
Mono-Di

(one big baby and one small)
Twin type:

division of fertilized ovum
Monozygotic
Twin type:

fertilization of two ova by two sperm
Dizygotic
Monozygotic Twins:

separation after amnion formation
Monochorionic-Monoamnionic

(highest mortality rate)
Dx:

pregnant woman with HTN, edema, proteinuria
Preeclampsia
(3) risk factors for onset of Preeclampsia
Nulliparity,

Multiple gestation,

Chronic HTN
Tx for Preeclampsia near term and preterm
Near term:
Delivery

Preterm (and Eclampsia Tx):
Mag sulfate - against seizures
Hydralazine - HTN
with Eclampsia, what percentage of patients have seizures before labor, during labor and after labor?
Before: 25%

During: 50%

After: 25%
what anti-hypertensives are given to mothers with chronic HTN during birth?
(2)
Nifedipine


Labetolol
what tests should be performed if patient has chronic HTN w/ pregnancy?
(2)

why?
Baseline ECG,
24-hr urine collection

helps differentiate superimposed preeclampsia
How common is gestational diabetes?
approx 15% of pregnancies
(3) fetal complications of Gestational Diabetes
Macrosomia,

Shoulder dystocia,

neonatal Hypoglycemia
when is a C-section indicated in gestational diabetes?
if fetal weight > 4500g
How is the DM-1 patient managed during pregnancy?

Delivery?
Pregnancy - insulin pump

Delivery - insulin drip
What gestational age of onset would you stop considering using a tocolytic agent?

A steroid agent?

What is done after that?
Tocolytic: >34 weeks

Steroid: >36 weeks

then: Expectant management
how are lower UTIs treated versus pyelonephritis in pregnancy?
Lower UTI - oral Abx

Pyelonephritis - IV Abx
(2) complications of pyelonephritis during pregnancy for mother
Septic shock


ARDS
what can Bacterial Vaginosis cause during pregnancy?
Preterm delivery
Leading cause of Neonatal sepsis

Tx?
Group B strep


Tx:
Ampicillin
Dx:

maternal fever, uterine tenderness, high WBC, fetal tachycardia

Tx? (2)
Chorioamnionitis


Tx:
Delivery,
IV Abx
Dx:

nausea and vomiting in pregnancy to the extent where the patient cannot maintain adequate hydration and nutrition

(3) Tx?
Hyperemesis Gravidarum

Tx:
IV hydration,
Electrolyte repletion,
Antiemetics
Management of women w/ Epilepsy during pregnancy
(3)
check antiepileptic drug levels monthly,

Level 2 Ultrasound at 19 - 20 weeks,

supplement w/ Vitamin K from 37 weeks to delivery
what do women w/ mild renal dz have a risk of getting during pregnancy?
(2 pregnancy problems)
Preeclampsia,

IUGR
Leading cause of maternal death
Pulmonary emboli
Tx for pregnancy-related DVT and PE
Heparin
Management for Hyperthyroidism in pregnant woman
(3)
Thyroid-stimulating immunoglobulins (TSI) should be screened.

if elevated, screen for fetal goiter and IUGR

continue w/ PTU medication
Management for Hypothyroidism in pregnant woman
Synthroid

(Increased Synthroid requirements during preg for somone already on meds)
(3) common problems that can occur in the pregnant SLE patient.

what (3) meds can be used in these patients as prophylaxis?
Risk for:
Pregnancy loss,
IUGR,
Preeclampsia

Meds:
Low-dose aspirin,
Heparin,
Corticosteroids
how are Lupus flares and Preeclampsia differentiated in pregnancy?
Complement levels
SLE and Sjogren mothers with anti-Ro and Anti-La antibodies have risk of developing what fetal problem?
Fetus w/ Congenital Heart Block
Dx:

infant is delivered and has growth restriction, CNS problems, cardiac defects and abnormal facies
Alcohol abuse during pregnancy
(FAS)
Pregnancy Risk:

Caffeine > 150 mg/day
Spontaneous abortions
Pregnancy Risk:

Cigarette smoking
(4)
Growth restriction,

Abruptions,

Preterm delivery,

Fetal death
Pregnancy Risk:

Cocaine
(2)
Placental Abruption,

CNS defects in children
what is best for the pregnant woman on Heroin during pregnancy?
Quitting outright will endanger fetus--need to be enrolled in a methadone clinic, then quit after delivery
(2) central issues in the immediate postpartum period for the patient
Pain management,

Wound care
when do diaphragms and cervical caps need to be refitted postpartum?
6 weeks
what are the (3) hormonal contraceptives of choice postaprtum?
Why?
Depo-provera,

Norplant,

Progesterone-only minipill

b/c they are less likely to decrease milk production in breast-feeding patients
What are the causes of postpartum hemorrhage?
(6)*
Coagulation Defect;
Atony;
Rupture;
Placenta (POC) retained;
Implantation site bleed;
Trauma
CARPIT
what are the steps in managing a postpartum hemorrhage?
(4 steps)
1. R/O cervical/vaginal lacerations

2. if still bleeding:
give Uterotonic agents (Oxytocin)

3. if still bleeding:
D&C

4. if still bleeding:
Laparotomy w/ bilateral O'Leary sutures to tie off uterine arteries
Dx:
fever, high WBC, uterine tenderness 5 - 10 days post C-section

Tx?
(2)
Endomyometritis

Tx:
D&C
broad-spectrum Abx until afibrile for 48 hrs