Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
120 Cards in this Set
- Front
- Back
- 3rd side (hint)
Definition:
child at fertilization to 8 weeks |
Embryo
|
|
|
Definition:
child at 8 weeks to delivery |
Fetus
|
|
|
Definition:
Softening and cyanosis of the cervix at or after 4 weeks |
Goodell's sign
|
|
|
Definition:
softening of the uterus (after 6 weeks) |
Ladin's sign
|
|
|
Definition:
first trimester |
fertilization to 12 weeks
|
|
|
Definition:
second trimester |
12 weeks to 24 weeks
|
|
|
Definition:
third trimester |
24 weeks to delivery
|
|
|
Definition:
child delivery less then 24 weeks |
Priviable
|
|
|
Definition:
Quickening |
Patient's initial presentation of fetal movement
|
|
|
what are the changes in CO, HR, SV, TPR and BP during pregnancy?
|
Inc CO, HR, SV
Dec TPR, Dec BP (returns to nml >24 weeks) |
|
|
(4) Respiratory changes during pregnancy
|
Inc Tidal volume,
Inc PaO2 and PAO2, Dec lung capacity, Mild Respiratory Alkalosis |
|
|
(3) GI changes during pregnancy
|
Inc vomiting,
Dec motility (constipation), Prolonged gastric emptying (GERD) |
|
|
(4) Renal changes during pregnancy
|
Inc kidney size,
Inc GFR (by 50%) leading to... Dec BUN and Creatinine by 25%, Inc Renin, Aldosterone and Na absorption (balanced by Inc GFR) |
|
|
(4) Blood changes during pregnancy
|
Inc plasma volume (50%),
Inc RBC (20%), both percents lead to Dec Hct, possibly causing Iron deficiency anemia, Inc Fibrinogen and factors VII - X leading to... Inc Thromboembolism |
|
|
what hormones are maintained by the placenta in pregnancy?
(4) |
Estrogen,
hCG, hPL, Progesterone (after initial maintenance from corpus luteum) |
|
|
what causes increased Thyroid Binding Globulin?
how does this affect T3 and T4? |
Inc estrogen
T3 and T4 inc binding to TBG leading to low serum levels of free T3 and T4 |
|
|
what is the cause of gestational diabetes?
how? |
hPL
it is an insulin antagoinist (inc diabetic effect and leading to inc insulin and protein synthesis) |
|
|
what is the adequate amount of nutrition needed in pregnancy?
breast feeding? |
Pregnancy: 300 kcal/day
Breast feeding: 500 kcal/day |
|
|
how often should prenatal visits be?
|
every 4 weeks until week 28
week 28 - 36: every 2 weeks, 36 to term: every week |
|
|
when is genetic screening done?
what are the (3) main tests? |
during second trimester
(usu 15 - 20 weeks) MSAFP, b-hCG, Estriol |
|
|
which germ cell ovarian tumor has a different treatment method then the others?
what is the Tx? |
Dysgerminoma
Tx: Radiation |
|
|
what is tested in pregnancy b/t 27 and 29 weeks?
(3) |
Glucose Loading Test (for gestational diabetes),
Hematocrit (for iron levels), Glucose Tolerance Test if GLT is positive |
|
|
how is the Glucose Loading Test performed?
(2) |
give 50g oral glucose and check in one hour
if > 140 mg/dL, then do GTT |
|
|
How is a Glucose Tolerance Test performed?
What are the blood glucose values for fasting, one, two and three hour intervals? |
Fasting glucose:
give 100 g oral glucose and test at 1, 2 and 3 hours Gestational Diabetes = Fasting glucose > 105 mg/dL or any two values over 180, 155 or 140 respectively |
|
|
what can dehydration lead to later in pregnancy?
|
Braxton-Hicks contractions
|
|
|
what causes edema of lower extremities, feet and ankles, and hemorrhoids in pregnancy?
Tx? |
Compression of IVC and pelvic veins
Tx: elevating feet |
|
|
what is the best test for fetal lung maturity?
normal levels? |
Lecithin/Sphingomyelin ratio
nml > 2 |
|
|
describe a positive Non-Stress Test
|
2 increases in FHR in 20 min that are >15 beats above nml and for >15 seconds
|
|
|
describe a positive Oxytocin Challenge Test
|
3 contractions in 10 minutes
|
|
|
(5)* categories of the Biophysical Profiles
|
Test the Baby MAN!:
Fetal Tone, Fetal Breathing, Fetal Movement, Amniotic Fluid volume, NST (zero or 2 points each; nml is 8 - 10) |
Test the Baby MAN!
|
|
Definition:
multiple gestation w/ at least one IUP and at least one ectopic |
Heterotrophic Pregnancy
|
|
|
at what b-hCG levels should you detect an IUP on vaginal US?
|
IUP should be seen on US w/ b-hCG of
1500 – 2000 mIU/mL |
|
|
at what b-hCG levels should you detect a fetal heartbeat w/ trans-abdominal US?
|
Fetal heartbeat should be seen w/ b-hCG > 5000 mIU/mL
|
|
|
Tx for Ruptured Ectopic
|
Exploratory Lap
(and maintain fluid levels) |
|
|
what hormone best resembles b-hCG?
how? |
LH
they also have similar beta units (in addition to similar alpha) |
|
|
what is the criteria to use Methotrexate for an ectopic?
(2) |
ectopic must be < 3.5 cm,
w/o heartbeat |
|
|
what is the progesterone level in a nonviable intra- or extra-uterine pregnency?
|
< 5 ng/mL
|
|
|
what is the progesterone level in 98% of intrauterine pregnancies?
|
> 25 ng/mL
|
|
|
what does G5P2124 indicate?
|
Twins
|
|
|
Definition:
Spontaneous abortion time |
pregnancy ending < 20 weeks
|
|
|
Type of Abortion:
any IU bleeding < 20 weeks w/o dilation or expulsion of POC |
Threatened abortion
|
|
|
Type of Abortion:
death of embryo of fetus < 20 weeks w/ complete retention of POC (usu leads to complete SAB) |
Missed abortion
|
|
|
Type of Abortion:
no expulsion of POC, but bleeding and dilation of cervix such that viability is unlikely |
Inevitable abortion
|
|
|
(2) ways an incomplete abortion can be taken to completion in first trimester
|
D&C
Prostaglandins (Misoprotol) |
|
|
causes of abortion in second trimester
(4) |
Congenital abnormalities
cervical / uterine abnormalities, trauma, systemic Dz or infection |
|
|
(3) ways an incomplete abortion can be taken to completion in second trimester
|
D&E,
Prostaglandins (Misoprostol), Oxytocin at high doses |
|
|
Definition:
Painless dilation leading to infection, Preterm Premature Rupture of Membranes (PPROM) or PTL |
Incomplete cervix
|
|
|
what should be done if patient is in first trimester and has a history of incomplete cervix?
when? |
Cerclage
12 - 14 weeks |
|
|
(3) tests to verify if patient has ruptured membranes
|
Pool - collection of fluid in vagina
Nitrazine - turns blue (alkaline) Ferning |
|
|
Definition:
Rupture of membranes > 1 hour before onset of labor |
Premature Rupture of Membranes
(PROM) |
|
|
(5) parts of a Bishop score
|
Dilation,
Effacement, Station, Cervical consistency, Cervical position |
|
|
Bishop score points zero - 3 for:
Dilation |
zero: Closed
1 point: 1 - 2 2 points: 3 - 4 3 points: > 5 |
|
|
Bishop score points zero - 3 for:
Effacement |
zero: 0 - 30%
1 point: 40 - 50% 2 points: 60 - 70% 3 points: > 80% |
|
|
Bishop score points zero - 3 for:
Station |
zero: -3
1 point: -2 2 points: -1 to zero 3 points: +1 - +3 |
|
|
Bishop score points zero - 3 for:
Cervical consistency |
zero: Firm
1 point: Medium 2 points: Soft 3 points: (none) |
|
|
Bishop score points zero - 3 for:
Cervical position |
zero: Posterior
1 point: Mid 2 points: Anterior 3 points: (none) |
|
|
Definition:
Lengthening (thinning) of the cervix |
Effacement
|
|
|
Definition:
relationship of fetal occiput to maternal pelvis |
Fetal Position
|
|
|
(4) ways to Induce labor
|
Pitocin,
Prostaglandins (Cervadil or Misoprostol), Mechanical dilation of cervix, Rupture of membranes (Amniotomy) |
|
|
MC 4 steps to Augment and monitor labor progress
|
water broke?
if not -> Amniotomy change? if not -> IUPC change? if not -> Pitocin change? if not -> C-section |
|
|
what does an IUPC measure with respect to contractions?
(2) |
1. Time of contraction
2. Strength of contractions |
|
|
Name the (6)* movements of labor in order and what each means
|
Engagement - biparietal diameter (largest) part of head enters pelvis,
Flexion - smallest diameter of head enters, Descent - head completely into pelvis, Internal rotation - from OT to OA or OP, Extension - vertex passes beyond pubic synthesis; crowning occurs External rotation - after delivery of the head as the head rotates to face forward |
Every Fetus Delivers Involving Excited Externs
|
|
(3) P's of the Active Phase that may cause problems in delivery
|
Power
(strength of contractions), Passenger (size and position of infant), Pelvis (shape) |
|
|
(5) steps of Tx in patient w/ Non-reassuring fetal status
|
1. Give mother oxygen mask
2. turn her to Left side to decrease IVC compression 3. D/C Pitocin 4. if due to Hypertonus (long contraction) or Tachysystole (>5 contractions in 10 min), give Terbutaline to relax uterus 5. If 1 – 4 does not work, C-section patient |
|
|
Dx:
Painless vaginal bleeding in the third trimester Tx for perterm patient (<36 weeks)? (3) Tx for term patient? |
Placenta previa
Tx for Preterm: 1. Monitor in hospital 2. Transfusion PRN 3. Tocolytic to prolong until 36 weeks Tx for Term: C-section |
|
|
Dx:
Vaginal bleeding, painful contractions, firm and tender uterus Tx? |
Placental Abruption
Tx - Delivery (by C-section if mother or baby is unstable) |
|
|
Dx:
sudden onset of intense abdominal pain assoc w/ pregnancy Tx? |
Uterine rupture
Tx - immediate laparotomy |
|
|
Dx:
Vaginal bleeding and sinusoidal FHR pattern MCC? Tx? |
Fetal Vessel Rupture
MCC - Velamentous cord insertion Tx - emergency C-section |
|
|
Dx:
contractions and changes in cervix at < 37 weeks gestation |
Preterm Labor
|
|
|
The only Tocolytic approved by the FDA
MOA? |
Ritrodrine
MOA: Beta-agonist |
|
|
Tocolytic that acts as a calcium antagonist
|
Magnesium sulfate
|
|
|
what is the test to determine if patient is near a Magnesium sulfate toxicity?
|
check DTRs continuously...they are depressed less then the toxic level of 10 mg/dL
|
|
|
what Calcium channel blocker is used as a Tocolytic?
|
Nifedipine
|
|
|
what NSAID is used as a Tocolytic?
|
Indomethacin
|
|
|
MC concern w/ PROM?
|
Chorioamnionitis
|
|
|
when is it common to see maternal hypotension?
what can it cause in child? what is Tx for maternal hypotension? |
After epidural
causes - Fetal bradycardia Tx - IV hydration and Ephedrine |
|
|
Tx for fetal bradycardia lasting for longer then 4 - 5 minutes?
|
C-section
|
|
|
Monozygotic Twins:
separation before the differentiation of trophoblasts |
Dichorionic-Diamnionic
|
|
|
Monozygotic Twins:
separation after trophoblast differentiation and before amnion formation |
Monochorionic-Diamnionic
|
|
|
what type of twins can develop Twin-to-Twin Transfusion Syndrome?
|
Mono-Di
(one big baby and one small) |
|
|
Twin type:
division of fertilized ovum |
Monozygotic
|
|
|
Twin type:
fertilization of two ova by two sperm |
Dizygotic
|
|
|
Monozygotic Twins:
separation after amnion formation |
Monochorionic-Monoamnionic
(highest mortality rate) |
|
|
Dx:
pregnant woman with HTN, edema, proteinuria |
Preeclampsia
|
|
|
(3) risk factors for onset of Preeclampsia
|
Nulliparity,
Multiple gestation, Chronic HTN |
|
|
Tx for Preeclampsia near term and preterm
|
Near term:
Delivery Preterm (and Eclampsia Tx): Mag sulfate - against seizures Hydralazine - HTN |
|
|
with Eclampsia, what percentage of patients have seizures before labor, during labor and after labor?
|
Before: 25%
During: 50% After: 25% |
|
|
what anti-hypertensives are given to mothers with chronic HTN during birth?
(2) |
Nifedipine
Labetolol |
|
|
what tests should be performed if patient has chronic HTN w/ pregnancy?
(2) why? |
Baseline ECG,
24-hr urine collection helps differentiate superimposed preeclampsia |
|
|
How common is gestational diabetes?
|
approx 15% of pregnancies
|
|
|
(3) fetal complications of Gestational Diabetes
|
Macrosomia,
Shoulder dystocia, neonatal Hypoglycemia |
|
|
when is a C-section indicated in gestational diabetes?
|
if fetal weight > 4500g
|
|
|
How is the DM-1 patient managed during pregnancy?
Delivery? |
Pregnancy - insulin pump
Delivery - insulin drip |
|
|
What gestational age of onset would you stop considering using a tocolytic agent?
A steroid agent? What is done after that? |
Tocolytic: >34 weeks
Steroid: >36 weeks then: Expectant management |
|
|
how are lower UTIs treated versus pyelonephritis in pregnancy?
|
Lower UTI - oral Abx
Pyelonephritis - IV Abx |
|
|
(2) complications of pyelonephritis during pregnancy for mother
|
Septic shock
ARDS |
|
|
what can Bacterial Vaginosis cause during pregnancy?
|
Preterm delivery
|
|
|
Leading cause of Neonatal sepsis
Tx? |
Group B strep
Tx: Ampicillin |
|
|
Dx:
maternal fever, uterine tenderness, high WBC, fetal tachycardia Tx? (2) |
Chorioamnionitis
Tx: Delivery, IV Abx |
|
|
Dx:
nausea and vomiting in pregnancy to the extent where the patient cannot maintain adequate hydration and nutrition (3) Tx? |
Hyperemesis Gravidarum
Tx: IV hydration, Electrolyte repletion, Antiemetics |
|
|
Management of women w/ Epilepsy during pregnancy
(3) |
check antiepileptic drug levels monthly,
Level 2 Ultrasound at 19 - 20 weeks, supplement w/ Vitamin K from 37 weeks to delivery |
|
|
what do women w/ mild renal dz have a risk of getting during pregnancy?
(2 pregnancy problems) |
Preeclampsia,
IUGR |
|
|
Leading cause of maternal death
|
Pulmonary emboli
|
|
|
Tx for pregnancy-related DVT and PE
|
Heparin
|
|
|
Management for Hyperthyroidism in pregnant woman
(3) |
Thyroid-stimulating immunoglobulins (TSI) should be screened.
if elevated, screen for fetal goiter and IUGR continue w/ PTU medication |
|
|
Management for Hypothyroidism in pregnant woman
|
Synthroid
(Increased Synthroid requirements during preg for somone already on meds) |
|
|
(3) common problems that can occur in the pregnant SLE patient.
what (3) meds can be used in these patients as prophylaxis? |
Risk for:
Pregnancy loss, IUGR, Preeclampsia Meds: Low-dose aspirin, Heparin, Corticosteroids |
|
|
how are Lupus flares and Preeclampsia differentiated in pregnancy?
|
Complement levels
|
|
|
SLE and Sjogren mothers with anti-Ro and Anti-La antibodies have risk of developing what fetal problem?
|
Fetus w/ Congenital Heart Block
|
|
|
Dx:
infant is delivered and has growth restriction, CNS problems, cardiac defects and abnormal facies |
Alcohol abuse during pregnancy
(FAS) |
|
|
Pregnancy Risk:
Caffeine > 150 mg/day |
Spontaneous abortions
|
|
|
Pregnancy Risk:
Cigarette smoking (4) |
Growth restriction,
Abruptions, Preterm delivery, Fetal death |
|
|
Pregnancy Risk:
Cocaine (2) |
Placental Abruption,
CNS defects in children |
|
|
what is best for the pregnant woman on Heroin during pregnancy?
|
Quitting outright will endanger fetus--need to be enrolled in a methadone clinic, then quit after delivery
|
|
|
(2) central issues in the immediate postpartum period for the patient
|
Pain management,
Wound care |
|
|
when do diaphragms and cervical caps need to be refitted postpartum?
|
6 weeks
|
|
|
what are the (3) hormonal contraceptives of choice postaprtum?
Why? |
Depo-provera,
Norplant, Progesterone-only minipill b/c they are less likely to decrease milk production in breast-feeding patients |
|
|
What are the causes of postpartum hemorrhage?
(6)* |
Coagulation Defect;
Atony; Rupture; Placenta (POC) retained; Implantation site bleed; Trauma |
CARPIT
|
|
what are the steps in managing a postpartum hemorrhage?
(4 steps) |
1. R/O cervical/vaginal lacerations
2. if still bleeding: give Uterotonic agents (Oxytocin) 3. if still bleeding: D&C 4. if still bleeding: Laparotomy w/ bilateral O'Leary sutures to tie off uterine arteries |
|
|
Dx:
fever, high WBC, uterine tenderness 5 - 10 days post C-section Tx? (2) |
Endomyometritis
Tx: D&C broad-spectrum Abx until afibrile for 48 hrs |
|