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98 Cards in this Set
- Front
- Back
how do you correct myopia?
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with a concave lens
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pathway of aqueous humor
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produced by ciliary epithelium, flows into anterior chamber and out through trabecular meshwork and canal of Schlemm
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cell layers of the eye
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photoreceptors (rods and cones)
horizontal cell bipolar cell amacrine cell ganglion cell |
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more sensitive to scattered light; for night vision; lower acuity
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rods
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less photopigment; day vision; most sensitive to direct axial rays; high acuity
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cones
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what determines whether ganglion cells is "on-center" vs. "off-center"
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type of glutamate receptor that is expressed
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what type of ganglion cell projections mediate the pupillary reflex?
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W type
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where do P type ganglion cells project and what type of info do they carry?
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to layers 3-6
info about color vision |
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where do M type ganglion cells project and what type of info do they carry?
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to layers 1-2
infor about movement |
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6 neocortical layers from outside to inside
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molecular layer
external granular layer external puramidal layer internal granular layer internal pyramidal layer fusiform layer |
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which layer of neocortex is primary recipeient of thalamocortical inputs?
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layer IV
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which layer of neocortex is main source of projections to thalamus from cortex?
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layer VI
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what type of visual info does dorsal pathway carry and where does it go?
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motion
depth perception relative size parietal lobe |
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what type of visual info does ventral pathway carry and where does it go?
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object/form recognition
temporal lobe |
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what does vestibulooccular reflex do?
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keep eyes fixed on a target when the head is moving
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what makes endolymph and what is special about it?
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stria vascularis
K+ rich |
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lateral and medial vestibulospinal tract
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adjust head position and tone of body with movement of head
righting reflexes tonic neck reflexes |
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reticular formation
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for ANS responses to vestibular stimulation
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ventral posteroinferior nucleus and ventral posterolateral nucleus
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projects to postcentral gyrus for conscious perception of movement
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MLF
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links medial moving eye to lateral one
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attenuation reflex
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tensor tympani and stapedium muscle stiffen ossicles in response to loud sounds
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inner hair cells
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afferents
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outer hair cells
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efferents from superior olivary complex
exhibit electromotility |
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dorsal cochlear nuclei
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info about frequency
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ventral cochlear nuclei
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info about sound localization--go to sup. olivary nuclei and cross to both sides
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where is auditory space map made?
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inferior colliculus
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filiform
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no taste receptors
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fungiform
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throughout tongue
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foliate
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along back of tongue along edges
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vallate
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back of tongue--have about 1/2 of tast receptors
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what does pineal produce?
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melatonin
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epithalamus
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pineal gland and habenular nuclei
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purpose of epithalamus
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way for limbic structures and olfactory stimuli to affect brainstem reticular formation (behavior)
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what results from damage to subthalamus
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hemiballism
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what thalamic nucleus does not project to the cerebral cortex?
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reticular thalamic nucleus
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tonic mode
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slight depolarization results in discharge; hyperpolarization results in inhibition--transmits patterned info accurately
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burst mode
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no transmission of specific info
slight depolarization opens special voltage gated calcium channels |
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three types of thalamic nuclei
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relay nuclei
association nuclei nonspecific nuclei |
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fxn of relay nuclei
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receive well defined input and project to functionally distinct areas of cortex
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fxn of association nuclei
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most input from cerebral cortex and project to association areas of cerebral cortex--maintain normal level of cortical activity and may regulate communication between cortical areas
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fxn of nonspecific nuclei
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receive input from midbrain reticular formation, project widely in cerebral cortex
ascending reticular activating system damage can result in coma |
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ascending reticular activating system
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see activity in midbrain when drowsy, but acitivity in thalamus when alert
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what separates the thalamus into regions?
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internal medullary lamina
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input to ventral posterolateral nucleus
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medial lemniscus
spinothalamic |
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input to ventral posteromedial nucleus
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trigeminothalamic-->projects to primary somatosensory area in postcentral gyrus
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fxn of ventral tier of lateral region of thalamus
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somatosensory
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ventral lateral nucleus
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inputs: cerebellar afferents (dentate) and basal gangia
projects to primary motor area of precentral gyrus al to premotor area |
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fxn of ventral lateral nucleus
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involved in movement especially planning and initiating
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dorsal tier of lateral region of thalamus
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pulvinar, lateral posterior and lateral dorsal nuclei
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input and projection of dorsal tier of lateral region of thalamus
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inputs: superior colliculs and association cortex
projects to secondary visual areas and to parieto-temporo-occipital association area |
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fxn of dorsal tier of lateral region of thalamus
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attention and eye movement; probably plays some role in directing attention
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metathalamus
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medial (auditory) and lateral (visual) geniculate
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anterior nucleus of thalamus
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afferents from hippocampus and mammillary bodies
projects to posterior cingulate cortex may fxn in learning and emotions |
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intralaminar nuclei
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centromedian and parafascicular nuclei
afferents from superior colliculus, piriform cortex, and ventral pallidum project to frontal eye fields and anterior cingulate cortex fxn in eye-head control and attn |
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centromedian nucleus
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input from globus pallidus
projects to area 4 and entire neocortex ? motor fxn |
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what separates thalamus and reticular nucleus?
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external medullary lamina
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reticular nucleus
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afferents from brainstem reticular formation, thalmocortical fibers, cortex
Fxns as part of thalamic feedback circuit ? important in sleep/wake |
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medial MD and midline nuclei
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afferents from solitary nucleus, substantia nigra, amygdala, and ventral pallidum
projects to insula, orbitofrontal and subcallosal cortex fxn in autonomic regulation and emotion |
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motor unit
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single alpha motor neuron and all the muscle fibers it attaches to
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motor pool
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group of neurons going to muscle
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Type I muscle fibers
(red/slow) |
small fiber size
small neuron size moderate speed of contraction low tension high aerobic metabolism fatigue resistant |
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Type II muscle fibers
(white/fast) |
large fiber size
large neuron size very fast speed of contraction high tension low aerobic metabolism fatigues easily |
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what do most descending tracts synapse on?
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interneurons
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lateral motor neurons go to?
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limbs
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medial motor neurons go to?
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axial muscles
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tracts that run in lateral funiculus have stronger influence on?
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limbs
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tracts that run in ventral horn control?
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axial muscles
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rubrospinal tract
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arises from red nucleus
crosses at ventral tegmental decussation descends in lateral funiculus controls movements of more proximal limb flexor muscles |
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tracts that descend in MLF
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tectospinal
medial vestibulospinal pontine reticulospinal |
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characteristics of tracts that descend in MLF
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do not extend beyond upper thoracic region
distribute bilaterally mainly control axial muscles |
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tectospinal tract
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from superior colliculus with input from cortex, visual, auditory, and somatic sensory systems
descends in MLF and anterior funiculus terminates in medial part of intermediate gray crosses at dorsal tegmental decussaion generates reflex head and eye movement to orient to sudden stimuli |
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pontine reticulospinal
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originates in pontine reticular formation
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medial vestibulospinal tract
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from medial vestibular nucleus
terminates bilaterally in medial part of ventral horn reflex adjustment of head position to vestibular stimuli |
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lateral vestibulospinal tract
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from lateral vestibular nucleus
runs lenght of spinal cord in ventral part of lateral funiculus terminates ipsilaterally at all levels powerfully excites extensor motor neurons |
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reticulospinal tracts
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control generalized, gross movements, regulates gamma motor neuron activity and sensory transmission
strongly associated with muscle tone--stabilizes trunk as you move activated by corticobulbar tract predominantly inhibitory to reflexes |
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corticospinal tract
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voluntary command for movement; can regulate sensory transmission through dorsal horn
arises from motor cortex from Betz cells axons traverse posterior limb of internal capsule run through basal pons and comprise pyramids converge at internal capsule |
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corticobulbar tract
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cortex to brainstem
affect cranial nerve nuclei, sensory transmission nuclei activate brainstem nuclei involved in movement project to pons for relay to cerebellum |
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reticular formation
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affect muscle tone, autonomic responses, and level of alertness
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fxn of cerebellum
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modulates movement--detects motor error and provides corrections to improve performance
regulates activity of upper motor neurons in descending motor pathways |
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cerebellar input pathways
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contralateral from cerebral cortex (via pontine nuclei)
ipsilateral from vestibular nuclei, inferior olive, and cord |
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output from cerebellum
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motor cortex via deep cerebellar nuclei and thalamus
superior colliculus brainstem motor centers like reticular formation and vestibular nuclei |
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superior cerebellar peduncle connects?
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cerebellum and midbrain
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middle cerebellar peduncle connects?
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cerebellum and pons
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inferior cerebellar peduncle connects?
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cerebellum and medulla
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vestibulocerebellum
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flocculus and nodulus
posture, balance, reflex eye movements |
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spinocerebellum
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vermis and intermediate zone
regulates muscle tone and adjusts ongoing movements |
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cerebrocerebellum
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planning and initiation of skilled movements
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paired deep cerebellar nuclei from medial to lateral
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fastigial
interposed (globose and emboliform) dentate |
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mossy fibers have cell bodies where?
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pontine nuclei
vestibular nuclei spinal cord |
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climbing fibers have cell bodies where?
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inferior olive of medulla
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what do mossy and climbing fibers do?
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EXCITE Purkinje cells
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what do parallel fibers do?
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make excitatory connections wiht multiple Purkinje cell that lie in same transverse plane--excitation occurs in rows
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what else do parallel fibers excite and what do they do?
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inhibit Purkinje cells
stellate cells basket cells (lateral inhibition) golgi cells (reduce granule cell activity) |
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what are the source of output from cerebellar cortex?
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Purkinje cell axons
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Purkinje cells are what?
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INHIBITORY
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what does vermis receive info from?
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trunk muscles
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what does intermediate zone receive info from?
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limb muscles
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what do cerebellar lesions cause?
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persistent errors in movement
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