Quarter 2, Histology, Test 1, Extramural: Liver

Front 1

bilirubin comes to the liver from the spleen as a biproduct of the break down of...

Back 1

RBC's

Front 2

in the liver bilirubin is conjugated to...

Back 2

glucuronic acid

Front 3

the nucleus of hepatocytes are often...

Back 3

spherical and euchromatic with one or more prominent nucleoli

Front 4

in hepatocytes what is responsible for synthesis of lipids, bile salts for bile, and degredation/detox

Back 4

SER

Front 5

what cuses the number of lipid droplets in the hepatocyte to increase

Back 5

damage (ethanol)

Front 6

what is the name of the lumen of the secretory acinus in the liver

Back 6

bile canaliculus

Front 7

the lateral surface of hepatocytes extends from tight junction to ...

Back 7

space of Disse

Front 8

what surface of the hepatocyte is closely associated with hepatic sinusoids

Back 8

basal surface

Front 9

what is the area called that has a few reticular fibers, no fibroblasts, some adipose, dupfer cells, and is adjacent to basal surface of hepatocytes

Back 9

space of disse

Front 10

hepatic sinusoids separate each plate of ...

Back 10

hepatocytes

Front 11

what type of cells are located in the space of Disse, and are fibroblast like cells that accumulate lipid and Vitamin A

Back 11

Fat Storing Cell

Front 12

what cells are found in the walls of hepatic sinusoids and are monocyte derived macrophages

Back 12

kupfer cells

Front 13

pathological conditions such as chronic alcoholism will lead to proleiferation and synthesizing collagen from what cell types

Back 13

fat storing cell

Front 14

in the liver, secreted products are secreted from the secretory acinus into...

Back 14

intercalated ducts

Front 15

trace the flow of secreted products from the bile canaliculi to the common hepatic duct

Back 15

bile canaliculi, bile ductules, interlobular ducts, depatic ducts, common hepatic duct

Front 16

what type of epithelium would be found in bile ductules

Back 16

simple low cuboidal

Front 17

interlobular bile ducts are associated with what two other structures

Back 17

interlobular helpatic artery and interlobular portal vein

Front 18

what three structures form the portal triad

Back 18

interlobular bile ducts, hepatic artery, and portal vein

Front 19

plates of hepatocytes are organized around ...

Back 19

central vein

Front 20

what separates plates of hepatocytes

Back 20

sinusoids

Front 21

trace the blood flow through hepatic lobule from the portal vein to the vena cava

Back 21

right and left portal vein, conducting branches of interlobular branches of portal vein, terminal branches or portal vein, sinusoid, central vein/terminal hepatic venule, sublobular vein, collecting tributaries of hepatic vein, hepatic vein, inferior vena cava

Front 22

in zone 1 (periportal) the oxygen is high and there are a lot of nutriets which means

Back 22

more mitochondria and golgi

Front 23

in zone 2 (intermediate) there is intermediate levels of oxygen and nutrients leading to...

Back 23

intermediate levels of mitochondria and golgi

Front 24

in zone 3 (pericentral) there is low levels of oxygen and nutriets leading to...

Back 24

few mitochondria and increased peroxisomes and lipid droplets

Front 25

during fasting, which zone would run out of glycogen first

Back 25

zone 3

Front 26

what is the name of the stroma that surrounds the liver

Back 26

Glisson's capsule

Front 27

which theory of organization puts the central vein in the center, portal canals and limiting plate are the boundary, and emphasize relationship between lobule and venous drainage

Back 27

classical hepatic lobule

Front 28

what idea of liver organization puts the portal canal in the center of lobule, and central veins demarcate boundary of portal lobule, emphasizing relationship of lobule to duct system

Back 28

portal lobule

Front 29

which idea of liver organization has the termianl cranches of portal vein/hepatic artery at center, and central vein and portal canal demarcate boundary which emphasizes the relationship of the acinus and plates of cells

Back 29

liver acinus

Front 30

what type of epithelium is in the bile ducts and galbladder

Back 30

simple columnar

Front 31

the bile ducts and galbladder lack what part of the mucosa

Back 31

muscularis mucosae

Front 32

in the gallbladder the connective tissue is ___ but in the ducts it is more ___

Back 32

loose/dense

Front 33

in the galbladder there is an interwoven smooth muscle that runs in many directions called...

Back 33

tunica muscularis

Front 34

does the gallbladder have an adventitia or serosa

Back 34

serosa

Front 35

what are the names of the invaginations of surface epithelium that increase with age in the galbladder

Back 35

Rokitonsky-aschoff sinuses

Front 36

in the liver what are bile salts synthesized from

Back 36

cholesterol

Front 37

where are most plasma proteins synthesized

Back 37

liver

Front 38

what two membrane bound organelles are responsible for metabolizing foreign compounds via oxidation

Back 38

SER and peroxisomes

Front 39

what component of the hepatocyte is responsible for the synthesis of lipids and bile salts

Back 39

SER

Front 40

what is found in the SER that is reponsible for the detox of drugs, and environmental toxins

Back 40

Cytochrome C

Front 41

which part of the hepatocyte is responsible for metabolizing long chain fatty acids and synthesizing bile acids

Back 41

peroxisomes

Front 42

the hepatocyte apical membrane has short ___ that protrude into the lumen of the bile canaliculus

Back 42

microvilli

Front 43

what type of cell in the liver lacks a continuous basal lamina

Back 43

heaptocytes

Front 44

under pathological conditions, what cells in the liver will synthesize collagen fibers

Back 44

fat storing cells

Front 45

what is another term for the central vein

Back 45

terminal hepatic venule

Front 46

simple tubular ___ secreting glands may be present in the neck of the gallbladder

Back 46

neck