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25 Cards in this Set
- Front
- Back
- 3rd side (hint)
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Renal veins vertebral level
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L1-L2
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Femoral veins merge at what vertebral level
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L4-L5
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What variables effect filtration coefficient
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area and permeability
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What do you give 2 hours after first incision for prophylaxis during surgery?
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1st gen ceph
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What is special about myocardial tissue?
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It extracts more oxygen than any other tissue
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Drug induced tubular necrosis
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Sulfonamides, Methotrexate, Intravenous acyclovir, triamterene
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MC drug causing allergic interstitial nephritis
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Methicillin
other common drugs? |
Cephalosporins, Acetazolamide, Allopurinol, Sulfonamides, NSAIDS
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Chronic interstitial nephritis
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Lithium and cyclosporine
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Anaphylactic Shock
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Epinephrine
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Describe MOA of bile acid resins
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They interrupt enterohepatic circulation of excreted bile, causing liver to make more bile which requires cholesterol--thus it must draw cholesterol from circulating LDL.
End effect --> reduction in LDL Side effect: The bile has a high concentration of cholesterol --> gall stones. Other side effects? |
Hepatotoxic(increase LFT) and myositis.
What other drugs have rhabdomyolysis? (Statins) |
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Painful foot ulcers, exertional calf pain
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Buerger's disease
rare quality? |
extends into nerves and veins...inflammatory process may encase all three vessels(nerve, vein, artery) in fibrosis
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transmural inflammation of the arterial wall with fibrinoid necrosis
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characteristic of PAN
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MAIN effect is raising HDL
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Niacin
Side effects? |
flushed face, hyperglycemia(careful to use in diabetics...acanthosis nigricans), hyperuricemia(gout)
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MAIN effect is reducing LDL
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Statins
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MAIN effect is reducing TG
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fibrates
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Slightly increased TG
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Bile Acid Resins
also slightly increases HDL |
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ONLY effects LDL
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Cholesterol Absorption inhibitor - Ezetimibe
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Gray Man/Gray Baby/Red Man
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Amiodarone/Chloramphenicol/Vancomycin
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What drug administered with statins will reduce their absorption?
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Bile acid resins
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What drug is a/w a very annoying red flushed face side effect?
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Niacin.
What can you do to prevent this? |
Administer with aspirin. Will also eventually go away with long term use.
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Renal artery stenosis in female 20-30s
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fibromuscular dysplasia
60-70s old person? |
Atherosclerosis
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Marked hypertrophy of one kidney
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due to renal artery stenosis CLASSIC
What signs are specific for this disease? |
hypertension and abdominal/flank bruit
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Side effect gynecomastia
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K+ sparing diuretics -- aldosterone antagonists
Spironolactone, Triamterine, Amiloride, Epleronone |
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Side effect gingival hyperplasia
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non-DHP CCB
Verapamil, Diltiazem |
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first dose HYPOtension
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-zosin drugs(alpha 1 blockers)
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