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11 Cards in this Set

  • Front
  • Back
What is the presentation of Glyceryl Trinitrate ?
Sublingual spray 400mcg aerosol metered dose
What is Glyceryl Trinitrate?
A potent vasodilator
What are 3 main drug actions of Glyceryl Trinitrate?
* dilation of coronary arteries/relief of coronary spasm
* dilation of systemic veins veins resulting in lower pre-load
* reduced blood pressure
Where is Glyceryl Trinitrate Absorbed?
bucccal mucosa and liver
What are the indications for giving Glyceryl Trinitrate?
*Suspected A.M.I or myocardial ischemia
*Cardiogenic pulmonary oedema
What are 5 contra-indications for Glyceryl Trinitrate?
*ksar
*CVA (current episode)
*head trauma
*Systolic BP <100
*Sildenafil(Viagra) in past 6 hours, 6 - 12 hrs BP <140, 12 - 24 hrs BP <120 .
What are 4 precautions for the use of Glyceryl Trinitrate?
* Cerebral vascular disease
* Risk of syncope/hypotension
* enhanced effects woth alcohol
* Viagra in past 4 days
What are 6 side effects of Glyceryl Trinitrate?
*Hypotension
*Syncope
*Dizziness
*Vascular headaches
*Tachycardia
*Facial flushing
What is the onset ,peak and duration times for Glyceryl Trinitrate given sublingual ?
Onset - 30secs-2 mins
Peak - 4 mins
Duration - 20 - 30 mins
What dose of Glyceryl Trinitrate would you give for a suspected MI or Cardiogenic pulmonary oedema ?
400mcg every 5mins providing BP>100mmHg systolic
What dose of Glyceryl Trinitrate would you give for a child ?
Not approved