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16 Cards in this Set
- Front
- Back
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Define steatosis
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fatty change
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Which stains stain fat?
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Oil-red-O
Sudan Black |
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What are some pathologic accumulations of cholesterol?
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-Atherosclerosis
-Xanthomas -Foamy macrophages -Cholesterolosis of gallbladder |
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Seen in alcoholic liver disease, what are accumulations of proteins in plasma cells called?
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Russell Bodies
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Which stain stains amyloid orange which, when polarized, turns apple-green?
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Congo-red
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What are glycogen accumulations in the glomerulus called?
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Kimmelstiel-Wilson nodules
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Which stain stains glycogen?
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PAS (periodic acid-Schiff) with/without diastase (enzyme)
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What are two classic examples of exogenous pigments?
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-Carbon/coal (anthrocotic pigment)
-Tattooing |
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What are four classic examples of endogenous pigments and what are their special stains?
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-Lipofuscin (PAS)
-Melanin (Fontana stain or Fontana-Masson stain) -Iron/Hemosiderin (Prussian blue positive) -Bilirubin (Prussian blue negative) |
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Which four immunoperoxidase stains are useful in determining melanoma from carcinoma?
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-HMB-45
-S-100 -Melan-A -Bimentin |
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What are the two forms of pathologic calcification?
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-Dystrophic calcification
-Metastatic calcification |
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Which stain stains calcium?
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Von Kossa stain; rarely used
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What are laminated dystrophic calcifications called?
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Psammoma bodies
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What refers to any form of glassy, eosinophilic (pink), relatively acellular change in H&E sections?
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Hyaline Change
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What are two classic locations of hyaline change?
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-Uterine leiomyomas
-Fibroadenomas of the breast |
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What is a cause of DNA and protein damage that leads to cellular aging?
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Free radicals
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