Pulmonary Pharmacology

Front 1

salmeterol

Back 1

LABA

Front 2

albuterol

Back 2

SABA

Front 3

pirbuterol

Back 3

SABA

Front 4

metaproterenol

Back 4

SABA

Front 5

levalbuterol

Back 5

SABA

Front 6

Formoterol

Back 6

LABA

Front 7

Arformoterol

Back 7

LABA

Front 8

adverse effects associated with beta2 agonists

Back 8

tremor, tachycardia, cardiovascular events

Front 9

used for acute asthma (bronchoscpasm) attack

Back 9

SABAs

Front 10

associated with tachyphylaxis in prophylaxis use

Back 10

SABAs

Front 11

when used alone, they increase asthma mortality, need to be used in combination with corticosteroids

Back 11

LABAs

Front 12

two drugs that block bronchoconstriction mediated by vagal discharge

Back 12

ipatropium
tiotropium

Front 13

uses for antimuscarinics in asthma

Back 13

bronchodilator in asthma and COPD

Front 14

adverse effects of antimuscarinics

Back 14

dry mouth, cough, dilated pupil

Front 15

mechanism of axn for inhaled cortisosteroids

Back 15

inhibitors of phospholipase A2, reduces expression of COX

Front 16

associated with decreased production of prostaglandins, leukotrienes, and increase responsiveness of Beta adrenergic receptors

Back 16

corticosteroids

Front 17

drug of choice for prophylaxis treatment of asthma

Back 17

inhaled corticosteroids

Front 18

associated with pharyngeal candidiases and adrenal suppression

Back 18

inhaled corticosteroids

Front 19

Budesonide

Back 19

corticosteroid

Front 20

Triamcinolone

Back 20

corticosteroid

Front 21

Fluticasone

Back 21

corticosteroid

Front 22

Mometasone

Back 22

corticosteroid

Front 23

Flunisolide

Back 23

Corticosteroid

Front 24

Beclomethasone

Back 24

Corticosteroid

Front 25

Ciclesonide

Back 25

corticosteroid

Front 26

two drugs that are antagonists of LTD4 receptors

Back 26

Zafirlukast
Montelukast

Front 27

inhibitor of 5-lipoxygenase

Back 27

Zileuton

Front 28

associated with decreased production of leukotrienes

Back 28

Zafirlukast
Montelukast
Zileuton

Front 29

associated with Churg-Stauss syndrome (allergic granulomatous angiitis)

Back 29

LTD4 receptor antagnoists
Zafirlukast
Montelukast

Front 30

IgE antibody antagonist

Back 30

Omaluzimab

Front 31

PDE inhibitor cause intracellular rise in cAMP in mast cells and airway smooth muscle

Back 31

Theophylline
decrease release of mediators from mast cells
smooth muscle relaxation

Front 32

prophylactic treatment of nocturnal asthma attacks

Back 32

theophylline

Front 33

adverse effects of theophylline

Back 33

insomnia, tremor, anorexia, seizures, arrhythmias

Front 34

prostacyclin (PGI2)

Back 34

epoprostenol

Front 35

analog of prostacyclin PGI2

Back 35

treprostinil
iloprost

Front 36

nonselective endothelin receptor antagonist

Back 36

bosentan

Front 37

selective type A endothelin-1 receptor antagonist

Back 37

Ambrisentan

Front 38

PDE-5 enzyme inhibitors

Back 38

sildenafil
Tadalafil

Front 39

drugs that prolong the effect of NO

Back 39

sildenafil
Tadalafil
*PDE-5 enzyme antagonists

Front 40

three drugs that are potent vasodilators and inhibitors of platelet aggregation

Back 40

epoprostenol
treprostinil
iloprost

Front 41

drugs used for pulmonary HTN that are contraindicated with nitrates

Back 41

bosentan
ambristentan
sildenafil
tadalafil

Front 42

drug that reduces the release of inflammatory and bronchoconstrictor mediators from mast cells

Back 42

cromolyn

Front 43

treatment cromolyn is used for

Back 43

prophylaxis treatment of asthma
allergies

Front 44

pulmonary drug associated with increasing histone deacetylase 2 activity and therefore useful in patients with COPD

Back 44

theophylline

Front 45

adverse effects associated with theophylline

Back 45

insomia, seizures, tremor, arrhythmias

Front 46

pulmonary HTN drug contraindicated in patients with LV dysfunction or blood clotting disorders

Back 46

epoprostenol