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46 Cards in this Set

  • Front
  • Back
salmeterol
LABA
albuterol
SABA
pirbuterol
SABA
metaproterenol
SABA
levalbuterol
SABA
Formoterol
LABA
Arformoterol
LABA
adverse effects associated with beta2 agonists
tremor, tachycardia, cardiovascular events
used for acute asthma (bronchoscpasm) attack
SABAs
associated with tachyphylaxis in prophylaxis use
SABAs
when used alone, they increase asthma mortality, need to be used in combination with corticosteroids
LABAs
two drugs that block bronchoconstriction mediated by vagal discharge
ipatropium
tiotropium
uses for antimuscarinics in asthma
bronchodilator in asthma and COPD
adverse effects of antimuscarinics
dry mouth, cough, dilated pupil
mechanism of axn for inhaled cortisosteroids
inhibitors of phospholipase A2, reduces expression of COX
associated with decreased production of prostaglandins, leukotrienes, and increase responsiveness of Beta adrenergic receptors
corticosteroids
drug of choice for prophylaxis treatment of asthma
inhaled corticosteroids
associated with pharyngeal candidiases and adrenal suppression
inhaled corticosteroids
Budesonide
corticosteroid
Triamcinolone
corticosteroid
Fluticasone
corticosteroid
Mometasone
corticosteroid
Flunisolide
Corticosteroid
Beclomethasone
Corticosteroid
Ciclesonide
corticosteroid
two drugs that are antagonists of LTD4 receptors
Zafirlukast
Montelukast
inhibitor of 5-lipoxygenase
Zileuton
associated with decreased production of leukotrienes
Zafirlukast
Montelukast
Zileuton
associated with Churg-Stauss syndrome (allergic granulomatous angiitis)
LTD4 receptor antagnoists
Zafirlukast
Montelukast
IgE antibody antagonist
Omaluzimab
PDE inhibitor cause intracellular rise in cAMP in mast cells and airway smooth muscle
Theophylline
decrease release of mediators from mast cells
smooth muscle relaxation
prophylactic treatment of nocturnal asthma attacks
theophylline
adverse effects of theophylline
insomnia, tremor, anorexia, seizures, arrhythmias
prostacyclin (PGI2)
epoprostenol
analog of prostacyclin PGI2
treprostinil
iloprost
nonselective endothelin receptor antagonist
bosentan
selective type A endothelin-1 receptor antagonist
Ambrisentan
PDE-5 enzyme inhibitors
sildenafil
Tadalafil
drugs that prolong the effect of NO
sildenafil
Tadalafil
*PDE-5 enzyme antagonists
three drugs that are potent vasodilators and inhibitors of platelet aggregation
epoprostenol
treprostinil
iloprost
drugs used for pulmonary HTN that are contraindicated with nitrates
bosentan
ambristentan
sildenafil
tadalafil
drug that reduces the release of inflammatory and bronchoconstrictor mediators from mast cells
cromolyn
treatment cromolyn is used for
prophylaxis treatment of asthma
allergies
pulmonary drug associated with increasing histone deacetylase 2 activity and therefore useful in patients with COPD
theophylline
adverse effects associated with theophylline
insomia, seizures, tremor, arrhythmias
pulmonary HTN drug contraindicated in patients with LV dysfunction or blood clotting disorders
epoprostenol