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15 Cards in this Set
- Front
- Back
What drugs to use if pt on previous antibiotic < 3mos
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1. Respiratory FQs (Moxi, Levo, Gemi)
2. Advanced Macrolide + Amox or Augmention 3. Advanced Macrolide + 2nd/3rd gen po Cephalosporin 4. Doxy maybe subsituted for Macrolide |
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What drugs to use if outpatient with co-morbidity
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Same as outpt healty pt on antibiotic <3mos
Check Sanford |
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What drugs to use if inpatient
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1. Advanced Macrolide + ceftriaxone or cefotaxime
2. Respiratory FQs Check Sanford |
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What drugs to use if inpatient ICU where pseudomonas is not an issue
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1. Ceftriaxone + azith or respiratory FQs
Remember to use 2 drugs to treat |
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How long to treat outpt
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Min of 5 days- no fever up to 3 days with <1 sign of clinical instability
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How long to treat pseudomonas
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2-3 weeks
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What is sequential streamlining
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Same drug w/ equi potentcy
( Doxycycline, linezolid, FQs, Bactrim) |
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What is switch streamlining
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different drug with equi potentcy
(AGs to levo, clindamycin to metronidazone) |
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What is step-down
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same or diff drug with less potentcy
(PCN and Cephalosporin and macrolide) |
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What drugs to use for VAP (ventilator assisted pneu) and HAP (hospital acquired pneu) in pts with no risk factors
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1. Ceftriaxone OR
2. FQs (levo, moxi, or cipro) OR 3. AMP/sulbactam OR 4. Ertapenem |
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What are RFs to suspect multiple drug resistance
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1. Pneu >5 days after hospitalization
2. Admitted from nursing home 3. recently on antibiotic 4. structural lung dx |
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What drugs to use in high risk pts with suspected multiple drug resistance
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Remember to use 2 drugs:
1. Ceftazidime OR Carbapenem OR beta-lactamase inhibitor (Zosyn) *NOTE: do not use if severe PCN allergy -PLUS- 1. FQ (cipro or levo) OR 2. Aminogly plus vanco or linezolid if MRSA suspected Check Sanford |
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What drugs to use in Acinetobacter
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1. Cabapenem OR
2. FQ + amikacin or ceftazidime 3. Amp/sulbactam (this is the active ingred) 4. colistin or polymyxin B |
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What is antibiotic cycling
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using diff rotation of combo of drugs to treat all pneus
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What is duration of therapy
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H.influ- 7-10 days
MSSA- 7-10 days but 21-28 days if cavitation Pseudo. aeru and aceinetobactor- 14-21 days |