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31 Cards in this Set
- Front
- Back
Pulmonary Embolism (PE)
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-Blockage of a pulmonary artery by thrombus, fat or air emboli and tumor tissue
-Most common pulmonary complication of hospitalized clients -50,000 die from PE each year -650,000 have nonfatal PE's |
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Etiology
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-Most PE's arise from thrombi in the deep veins of the legs (from upper extremities is rare)
-Presence of a DVT is often not suspected until a PE occurs -Develop from thrombi mobile clots that generally do not stop moving until they lodge in a narrow part of the circulatory system -Other sites of origin include: right side of heart (afib), pelvic vein (after childbirth or surgery), fat emboli (fractured long bones), air emboli (IV's), bacterial vegetation, amniotic fluid, and tumors. |
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Clinical Manifestations
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-Anxiety -- impending sense of doom
-Sudden onset of unexplained dyspnea, tachypnea, or tachycardia -Cough, pleuritic chest pain, hemoptysis, crackles, fever -Sudden changes in mental status -Massive PE may produce sudden collapse of the client with shock, pallor, severe dyspnea and crushing chest pain. The pulse is rapid and weak and BP is low. -Death in 60% of patients with massive emboli |
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Complications
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-Death
-Pulmonary Infarction -Pulmonary Hypertension |
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Pulmonary Infarction
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-Death of lung tissue
-Leads to alveolar necrosis and hemorrhage -Dead tissue can become infected and abscess (pleural effusion) |
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Pulmonary Hypertension
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-Occurs when >50% of the normal pulmonary bed is compromised
-Dilation and hypertrophy of right ventricle (cor pulmonale) leads to left-sided heart failure -Signs of right-sided heart failure (jugular vein distention, peripheral edema) |
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Diagnostic Studies
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-VQ Scan: Perfusion and Ventilation
-D-Dimer -Pulmonary Angiography if VQ scan is inconclusive -Spiral CT |
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VQ Scan
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-Perfusion Scanning - involves IV injection of a radioisotope - A scanning device detects the adequacy of the pulmonary circulation
-Ventilation Scanning -- Involves inhalation of a radioactive gas -- *Requires cooperation of the client |
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D-Dimer
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-Reccommended when PE is initially suspected
-Degradation product of fibrin -Normal D-Dimer can rule out PE -If elevated, a venous study is indicated to look for DVT -If DVT is located, PE is likely and anticoagulation therapy should be started -Patients with increased D-Dimer but normal venous ultrasound require a lung scan (VQ) |
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Pulmonary Angiogram
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-If lung scan (VQ) is inconclusive
-Invasive procedure that involves the insertion of a catheter through the antecubital or femoral vein, advanced to the pulmonary artery, and injection of contrast media -Allows visualization of pulmonary vascular and -location of the embolus -*Alert -- IV dye allergy (dye allergies and renal function need to be considered) |
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Spiral CT
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-Diagnostic tool of choice
-Relatively new noninvasive diagnostic test -Obtains continuous slices allowing visualization of the entire lung -The data can be computer reconstructed to allow for a 3D picture of the area to assist in emboli visualization |
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ABG - Arterial Blood Gases
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-Important
-Non-diagnostic -PAO2 low secondary to inadequate oxygenation secondary to occluded pulmonary vasculature -PCO2 is low because of hyperventilation -PH increases secondary to low PCO2 |
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Objectives of treatment
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-Prevent further growth of thrombi in the lower extremities
-Prevent embolization from the upper or lower extremities to the pulmonary vasculature -Provide cardiopulmonary support if indicated |
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Treatment -- Medical
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-#1! Keep on bed rest in semi-fowlers position or higher
-O2 -TPA fibrinolytic -Anticoagulation with heparin and coumadin -Turn, cough, deep breath -Digoxin/diuretics (if heart failure is present) -Pain control with narcotics |
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Anticoagulation
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-Heparin and coumadin are the anticoagulant drugs of choice
-Heparin started immediately and continued until the patient is therapeutic on coumadin -Heparin is adjusted according to PTT -Coumadin is adjusted according to INR |
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IV Heparin
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-Check the order
-Obtain an infusion pump -Check the patient's IV site -Obtain the heparin and the tubing -*What lab values do you need to know before starting the heparin??? (PTT, Platelets, INR) |
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Deliver 1000 units per hour of IV heparin
Available is 25,000 units in 500 mL of D5W Calculate mL/hr |
mL=500mL/25,000 units X 1000 units/hr = 500,000/25,000 = 20 mL/hr
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IV Heparin
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1. Set up concentration in mL/units
2. Set up mL/hr 3. Determine mL/hr |
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Thrombolytic Therapy
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-Agents such as TPA (tissue plasminogen activator) dissolve PE's and the source of thrombus in the pelvis or deep leg veins
-Decrease the chance of recurrent PE's -Many contraindications (chapter 33) -Risk of bleeding (much greater than heparin or coumadin) |
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Circulatory Support
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-Vasopressor agents may be necessary to support systemic circulation (increase BP)
-Digitalis and diuretics are used if heart failure is present |
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Treatment -- Surgical
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-Embolectomy
-Intracaval filter devices (IVC's) to prevent further pulmonary embolism |
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Pulmonary Embolectomy
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-If pulmonary arterial obstruction is severe (>50%), and patient does not respond to conservative therapy
-Rarely performed -High mortality rate -Pre-op pulmonary angiography is necessary to identify and locate the site of the embolus (must know exact location of PE) |
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Health Promotion
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-Risk factors parallel those for DVT (Table 37-7 Lewis)
-Prevention measures are the same as for the prophylaxis of DVT |
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Analysis/Diagnosis
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Actual:
-Impaired gas exchange -Ineffective breathing pattern -Anxiety |
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Analysis/Diagnosis (cont)
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Risk for ineffective therapeutic regime management
Potential Complications: -PC:Hypoxemia -PC:Impaired Tissue Perfusion -PC:Decreased Cardiac Output -PC:Bleeding |
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Acute Implementation
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-Bed rest in semi-fowlers postion or higher
-IV for meds and fluid therapy -Monitor for side effects of meds -O2 therapy as ordered -Careful monitoring of vital signs, O2 sats, EKG, ABG's, and lung sounds -Emotional support to decrease anxiety |
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Home Care
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-Treatment of underlying chronic diseases: diabetes, Afib, Obesity etc.
-Similar to that for the patient with DVT -Discharge planning aimed at preventing complications and recurrence -Reinforce regular follow-up care/INR monitoring -Teaching Guide Table 37-14 Lewis |
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Evaluations/Expected Outcomes
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-Adequate tissue perfusion and respiratory function
-Adequate cardiac output -Increased level of comfort -Absence of recurring PE/DVT -Absence of bleeding |
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Current Trends
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-Multislice Spiral CT scans are now becoming available that can collect even more data (more slices) than previous systems
-Increased public awareness -Arixtra SC once daily for the treatment of stabe patients with PE -Home self-monitoring of INR |
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Pleural Effusion
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Fluid in the thoracic cavity between the visceral and parietal pleura. It may be seen on a chest radiograph if it exceeds 300 mL
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cor pulmonale
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Hypertrophy or failure of the right ventricle resulting from disorders of the lungs, pulmonary vessels, or chest wall.
Signs of right-sides heart failure (jugular vein distention, peripheral edema) |