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24 Cards in this Set
- Front
- Back
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respiratory quotient
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CO2 production/O2 consumption
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compliance
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change in pressure/change in volume
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resistance
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pressure change/flow
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alveolar PO2
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150 - PaCO2/0.8
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A-a gradient
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PA02 - PaO2 (normal <10)
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Arterial PCO2
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Arterial PCO2 = PB - 47 x CO2 production/alveolar vent
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Oxygen content
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(1.39 x Hgb concentration x saturation) + (0.003 x PO2)
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O2 delivery
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cardiac output x arterial oxygen content
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O2 consumption
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CO x (arterial O2 content - venous O2 content)
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collapsing pressure
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2(tension)/radius
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physiologic dead space
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Vd = Vt x (PaCO2 - PeCO2)/ PaCO2
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drug-induced interstitial lung disease
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bleomycin, methotrexate, amiodarone, macrodantin, cyclophosphamide, nitrofurantoin, nitrosourea, methysergide, MTX, procarbazine
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isoproterenol
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relaxes bronch SM (beta 2)
tox: non-spec b agonist --> tach |
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albuterol
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relaxes bronch SM (beta2)
acute exacerbation |
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salmeterol
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long-acting agent for prophylaxis
tox: tremor, arrhythmia |
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theophylline
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class: methylxanthine
inh phosphodiesterase --> dec cAMP hydrolysis bronchodilation tox: p450 met |
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ipratropium
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class: muscuranic antagonist
compet block of receptors, prevents bronchoconstriction COPD use, and asthma |
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cromolyn
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prevents release of mediators from mast cell
use: prophylaxis only |
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beclomethasone, prednisone
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corticosteroids
5 actions 1st line against chronic asthma |
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zileuton
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anti-leukotrienes
5-lipoxygenase pathway inhibitor; blocks arachodonic acid to leukotriene |
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zafirlukast, montelukast
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anti-leukotrienes
blocks leukotriene receptors use: ASA induced asthma |
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guaifenesin
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expectorant
removes excess sputum, no cough suppression |
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n-acetylcysteine
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expectorant
loosens mucus plugs in CF acetaminophen antidote |
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cardiac output
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SVxHR
O2 consumption/ AV O2 difference |
