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4 Cards in this Set
- Front
- Back
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What is asbestos? |
Silicate mineral fiber previously used in insulation - peaked in 1980s, - there is a long latency period between exposure and disease developemtn (15-35 years) - At risk in construction, shipbuilding and mining industry |
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What is the pathophysiology of asbestosis lung disease? |
Deposits at level of airway bifrucations and alevoli - lung may clear shorter fibers, but others go into interstitum and lymphatics to the pleura -> alvelolitis in short term exposure --> macrophage and fibroblast production in irreversible chronic fibrosis |
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What are the types of asbestosis disease? |
Pleural plaques - smooth white raised irregular lesios on the parietal pleura - Pleural fibrosis: visceroparietal pleural reaction, can be localized or diffuse, can lead to symptomatic restrictive disease - Rounded ATX: mass like lesion that includes bronchi and vessels - asymptoamtic but can lead to respiratory impariment if large enoguh - Pleural effusion: eosinophils, exudative, bloody - Much higher risk of lung cancer; |
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What is silicosis? |
Related to exposure to silica dust, the most common form of which is quartz, - exposes workes that process silica containing rock or sand - upper load predominant small rounded noles --> can progressive and confluent to massive fibrosis - INhaled bronchodiolators, abx, O2, no reversal agent - Quit smoking, quit job lung transpolant - increased risk of TB and CTD |
