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32 Cards in this Set

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Passive Transport
movement of solute through gradient from high concentration to low concentration.
Active Transport
requires energy from ATP to move solutes from an area of lower concentration to an area of higher concentration. "swimming upstream"
Osmosis
Passive movement of fluid from an area with more fluid to one with less fluid
Osmolality
A measure of the number of solutes per kg of water.

Normal 275-295 mOsm/kg
Serum osmolality
2(Na) + glucose + BUN

Serum Osmo = 2(Na)

Reflects HYDRATION, not volume
Isotonic Solutions
Osmo 275-295 mOsm/L

0.9% NS
LR
Plasmalyte
Hypotonic Solution
Osmo <275

Water drawn into cells from ECF = swelling of cells

0.45% NS
0.35% NS
D5W
D 2.5W
Hypertonic Solutions
Osmo > 295

Pulls fluids from IC = cells shrinks

* therapeutic to reduce cerebral edema

3% NS
5% NS
Albumin
Oncotic Pressure
Pulling force of proteins.
Draws H2O into the vasculature
Colloid Oncotic Pressure
Pulling force exerted by protiens

Albumin "water magnet"

Pulls water back into the vasculature, capillary
Hydrostatic Pressure
Forces on fluids and solutes out through the capillary walls into interstitial fluid
Filtration
fluid movement between interstitial and vascular space

based on balance between oncotic and hydrostatic pressures
Edma Formation
-increased hydrostatic pressure

-decreased plasma oncotic pressure

-increased capillary membrane permeability (d/t infection, lymphatic obstruction)
Thirst Process
-increased EC fluid Osmolality

-drying mucous membranes

-stimulates hypothalamus

-drink water!
Aldosterone
From Adrenal Medulla

Retains NA and water
Antidiuretic Hormone
ADH "Vasopressin"

Stored in Posterior Pituitary gland in the hypothalamus

release is stimulated by low blood volume and increased serum Osmolality

cause retention of water
Atrial Natriuretic Peptide
ANP

cardiac hormone

increasing bp triggers release of ANP to stop rising bp

opposes RAAS
Anion Gap
Norm 3-11 mmol/L

Looks for cause of METABOLIC ACIDOSIS

AG = (Na) - (CL+HCO3)
hi gap >11
-DKA
-lactate
-salicylate toxicity
Conducting airways
upper airways
-nasopharynx
-oropharynx

no gas exchange occurs = anatomic dead space
Pulmonary compliance
distensibility of lungs
Pulmonary Ventilation
1 cycle if inspiration and expiration
Minute Ventilation
how many times you inhale and exhale per minute
Gas Transport Steps
1. Ventilation in lungs
2. Diffusion of O2 from alveoli into capillary blood
3. Perfusion of systemic tissues
4. Diffusion of CO2 from tissues to blood and returned to lungs
Boyle's Law
Low pressure = High Volume

High pressure = Low Volume

inversely proportionate
Haldane Effect
Removes O2 and attach CO2

Bloods ability to carry CO2

Deoxygenation of blood, increases ability to carry/attache CO2
Charles Law
Increase Volume = Increase Temp
Tidal Volume
Volume of air in 1 normal breath
Inspiratory Reserve Volume
Air in excess of tidal inspiration that can be inhaled with maximum effort
Expiratory Reserve Volume
Air in excess of tidal expiration that can be exhaled with maximum effort
Residual Volume
*Keeps alveoli open after expiratory reserve volume
SVR
Systemic Vascular Pressure:

Workload of L side of heart
Rocuronium
Dosing--card
Int. 0.6mg/kg (0.6-1.2)
Inf. 9-12mcg/kg/min