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13 Cards in this Set
- Front
- Back
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what is the current clinical syndrome definitino of ARDS?
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acute onset
bilateral infiltrate no HF paO2/FiO2 <200 |
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what are the radiologic findings is ARDS
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cloudy patchy bilateral ans assymetric alveolar inflitrates
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what pathologic changes occur in ARDS
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diffuse alveolar damage
hyaline membranes (dead type II cells) |
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direct lunge injury causes leading to ARDS
3 |
pneumonia (worst)
asp of gastric acid fat emoblism |
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indirect lung injury leading to ARDS
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spesis
trauma with shock acute pancreatitis drug overdose! |
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causes of death in ARDS (2)
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sepsis 50
resp. failure 25 |
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what are the 4 phases of ARDS
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1 exudative- develop hypoxemia
2 proliferative- lung comliance dec 3 fibrotic siffness worsens 4 recovery or death |
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exudative phase:
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develop hypox, bilat lung infltrates, put on ventilaro, protein fluid fills aveolar space, neturos invade, type II pneumos dies- hyaline membrane; no more surfactan
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proliferative phase:
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lung compliance dec, mor stiff, no surfact, requires higher pressure to vent, macrophages activate, cytokine storm
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fibrotic phase:
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stiffness becomes worse, lung responds by mobilizing fibroblasts to repair damage, if fails, die
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lung function of ARDS survivors:
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they can get up to 80% back
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treatment of ARDS:
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treat underlying condition
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what is the only successful treatment for ARDS?
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low tidal volume ventilation (6-7 ml/kg)
often pts given cistracurium so they cant overide ventilatro |
