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136 Cards in this Set

  • Front
  • Back
How many people are bitten in US annually?
500,000 to 1 million
Age group most at risk of getting bitten
Under 15 years
Most common bite-acquired infection requiring hospitilization
Pasteurella multocida
Most common bacteria in bite wounds
a-hemolytic Streptococcus
Anaerobes
List 5 risk factors for a bite wound getting infected
1. Victim over 50 years
2. Puncture wound prevents thorough cleansing
3. Bites on hands (joints and tendons here)
4. Delay of over 24h in seeking treatment
5. Inadequate debridement and irrigation immediately after bite
Syndrome caused by Capnocytophaga canimorous, a gram negative thin rod
DF-2, aka dysgonic fermentor
Where is DF-2 found?
Oral cavity of dogs, cats, ruminants
When is DF-2 most virulent?
In innumocompromised patients
Who is most at risk of acquiring DF-2 after a dog bite?
Immunocompromised individuals
Alcoholics
Splenectomized individuals
What are the clinical signs of DF-2 in dogs?
Asymptomatic
What are the clinical signs of DF-2 in humans?
Gram negative sepsis, with tropism for vascular endothelium and the endocadium
How can one prevent or control DF-2?
Clean bite wounds well
Prophylactic antibiotics for dog bited in at risk individuals
Disease caused by Bartonella hensleae, a small plieomorphic Gram negative bacillus
Cat scratch fever
How prevalent is Bartonella hensleae in healthy cats?
25-41%, most commonly in cats under 2 years
How is Bartonella acquired?
Cat bites, cat scratches, or cats licking wounds
How long may a cat carrying Bartonella hensleae transmit the agent?
Only for 2-3 weeks
Age group most commonly affected by cat scratch fever
Children (75% of cases!)
Benign self limiting disease characterized by tender regional lymphadenopathy that lasts for several months, and an intitial skin papule or pustule.
Bartonellosis/ Cat scratch fever
How frequently does Bartonellosis cause sore throat, malaise, fever, headache, splenomegaly, and stomach cramps?
Under 30% cases
How frequently does Bartonellosis lead to bacillary angiomatosis?
10% of cases
Proliferation of small blood vessels in skin and visceral organs in immunocompromised individuals. Caused by Bartonela hensleae.
Bacillary angiomatosis
Bartonellosis can cause a syndrome that may present as tonsilitis, encephalitis, cerebral arteritis, granulomatous hepatitis, pneumonia, or thrombocytopenic purpura
Bacillary angiomatosis
Lymphoma would be on the rule out list in a young adult with this infection, due to tender lymphadenopathy.
Bartonella hensleae
aka Cat scratch fever
How is bartonellosis treated?
LN aspiration, doxycycline, erythromycin, and rifampin
How can Bartonella hensleae be controlled?
Clean all scratches or bite wounds thoroughly
Avoid cat saliva, especially on open wounds
Flea control
Wash hands after handling cats
Declaw or put soft paws on cats
DImorphic fungus that forms yeasts in body tissues. Grows naturaly in soil.
Sporothrix schenkii
How is Sporothrix schenkii acquired?
Penetrating wound, rarely inhalation from soil
Man can acquire infection from cat without interruption of skin.
How do infected cats shed Sporothrix schenkii?
From wounds and in feces
This disease of cats causes small draining puncture wounds to appear on the extremities, head, and base of the tail. They may become cavitatied ulcers.
Sporotrichosis
Clinical signs of sporotrichosis in man
Ulcerated nodules
Painful lymphadenopathy
List three drugs used to treat Sporotrichosis
Iodides
Ketoconazole
Amphotericin B
How can sporotrichosis be controlled?
Wear exam gloves when examining draining lesions in cat
Proper cleaning of hands, forearms, and equipment
True or false: Sporothrix schenkii can penetrate intact skin
True
Mycobacterium isolate assocated with humans.
M. tuberculosis
Mycobacterium isolate associated with ruminants and cervids.
M. bovis
Mycobacterium isolate associated with fish and aquarium exposure.
M. marinum
3 ways in which Mycobacterium is transmitted.
Inhalation
Ingestion
Inoculation
Mycobacterium isolate becoming increasingly prevalent in AIDS patients.
M. avium
List three isolates of Mycobacterium that form the MAC complex seen in AIDS patients
M. avium
M. intracellulare
M. paratuberculosis
Isolate of Mycobacterium isolated from individuals with Crohn's disease and IBD.
M. paratuberculosis
With this infection, papules develop into non-healing painless ulcers with regional lumphadenopathy. Chronic pneumonia and wasting follow. Less commonly patients may get genitourinary infections, bone and joint involvement, or meningitis.
Mycobacterium
Clinical signs of Mycobacterium infection in animals
Granulomatous lesions in any organ and/or lymph nodes
Mycobacterium infections are treated with
Isonazid, rifampin
How can tuberculosis be controlled?
Pasteurize milk, TB testing of animal populations and removal of infected animals, wear gloves when handling infected animals.
Technical name for "Undulant Fever"
Brucellosis
Two species of Brucella that affect people most commonly
B. abortus
B. mellitensis
Two strains of Brucella that do not affect people.
B. neotomae
B. ovis
How is Brucella acquired?
Direct contact with fetal fluids
Ingestion of animal products
Inhalation during slaughter procedure
Accidental injection with strain 19 vaccine
This disease causes an intermittent fever, sudden onset septicemia, chills, and profuse sweating. Muscular weakness and exercise intolarance are also common.
Brucellosis
Possible complications of Brucellosis include...
encephalitis
meningitis
spondylitis
arthritis
vegetative endocarditis
Brucella may have a serologic cross reaction with this bacteria.
Yersinia entercolitica
How is Brucella treated? Why is treatment difficult?
Tertacycline, trimethoprim sulfa, doxycycline, and rifampin for 6 weeks
Difficult to treat b/c intracellular
How can Brucellosis be controlled?
Pasteurize milk, wear OB attire, gloves for vaccine administration, testing and removal
Agent that causes pseudotuberculosis
Yersinia pseudotuberculosis
Two ways in which man may acquire pseudotuberculosis
Contact with infected animals or ingestion of food contaminated with feces and/or urine from infected animals
Reservoir of pseudotuberculosis
Fowl and rodents

(Cats and dogs may be infected by eating reservoir hosts)
This disease in man appears with acute mesenteric lymphadenopathy, inflammed appendix, and inflammed iliocecal lymph nodes
Pseudotuberculosis
How does pseudotuberculosis present in cats?
Anorexia, gastroenteritis, jaundice, palpable mesenteric LN, hepatomegaly, splenomagaly
How does pseudotuberculosis appear in guinea pigs?
Enlarged mesenteric LN
Nodular abcesses in intestinal wall, spleen, and liver
Rapid weight loss/diarrhea
How may pseudotuberculosis be controlled?
Proper cooking of meat
Basic hygiene
Major reservoir of Yersinia enterolytica
Pigs
(Outbreaks also seen in puppies and kittens)
Clinical signs of Yersinia enterolytica in humans
Appendicitis like symptoms, diarrhea, abdominal pain
Age groups most susceptible to Yersinia enterolytica
Children and very old
How is Yersinia enterolytica acquired?
Ingestion (associated with chitterlings in particular)
Bacteria present in up to 85% of captive raised reptiles
Salmonella typhimurium
Two ways in which Salmonella may be acquired
Fecal-oral route
Inhalation of infected vacuum dust
Clinical signs of Salmonella infection
Self-limiting GI signs
List some of the CDC recommendations fro preventing transmission of Salmonella from reptiles to humans
1. Provide info to owners and potential buyers
2. Wash hands after handling reptiles or cages
3. Children under 5 and immunocompromised people should avoid reptile contact
4. Keep reptiles out of hoseholds with at-risk individuals
5. Reptiles should not be in child-care centers
6. Reptiles should not roam freely in homs
7. Pet reptiles should be kept out of kitchens
This motile, gram negative rod is s-shaped and causes gastroenteritis, bloody and non-bloody BM's, and abdominal pain.
Campylobacter jejuni
How long does it usually take to recover from Campylobacter jejuni?
7-10 days
How is Campylobacter jejuni treated?
Erythromycin
How is Campylobacter jejuni controlled?
Proper food preparation
Avoid fecal-oral transmission
General hygiene
List three bacterial species that may cause abortions in pregnant women.
Campyobacter fetus fetus
Brucella abortus
Listeria monocytogenes
Agent responsible for bubonic plague
Yersinia pestis
Disease associated with prairie dogs in Western US, also ground squirrels in California.
Yersinia pestis, aka bubonic plague
Yersinia pestis occasionally affects this domestic species
Cats who eat affected rodents
How is Yersinia pestis acquired? List three ways.
From infected flea bites of Xenopsylla cheopsis
Exposure through skin abrasions or animal bites
From infected cats with draining abcesses and/or pneumonia
Symptoms of bubonic plague include:
Vesicular lesion at site of exposure with subsequent lymphadenopathy (buboe formation) and septicemia
Pneumonic disease may either be secondary to conventional disease or primary if inhaled
Septic Yersinia pestis affects which body system?
CNS
List methods of control for Yersinia pestis
Insecticides and rodenticides
Proper handling of pneumonic cats and cats with lymphadnopathy-- gloves, eye protection, masks.
Agent responsible for tularemia
Francisella tularensis types A and B

A more virulent
Where was the last major outbreak of tularemia in the US?
Martha's VIneyard in the 1990's
Wild rabbits and hares serve as main source of this disease in North America
Tularemia
How do rabbits acquire tularemia?
Bites of Ixodes and Dermacentor ticks
How may tularemia be acquired?
Through scratches/cuts on skin
Through conjunctiva
Consumption of contaminated water or meat
Inhalation from dust or wool
Handling cats that recently caught sick animals
Sick cats
What are the clinical signs of tularemia in cats?
Malaise, oral ulcers, lymphadenopathy
What are the four forms of tularemia in man?
Ulceroglandular form (85%)
--necrotic ulceration and local lymphadenopathy
Oculoglandular form
Pneumonic form (most fatal!)
Typhoid form
--gatroenteritis
You are necropsying a rabbit and see that it has swollen lymph nodes, splenic abcesses, and liver necrosis and abcesses. You may very well be dealing with this zoonosis.
Tularemia
Two drugs used to treat tularemia
Streptomycin
Gentamycin
List four methods for controlling tularemia.
Wear gloves when necropsying or dressing animals
Properly cook game
Disinfect water
Insect repellent
This agent causes a disease that goes by Weil's Disease, Swineherder's Disease, or Stuttgart Disease
Leptospira
What environmental conditions does Leptospira prefer?
High humidity
Neutral to slightly basic soil
Warm temperatures
How can Leptospira be acquired?
Infected urine
Milk, placental material, fetuses
Contaminated water
This organism may penetrate mucous membranes, abrasions in the skin, and skin softened by water
Leptospira
Two serovars of Leptospira that dogs are vaccinated against commonly
L. canicola and L. icterhemorrhagicum
Three serovars of Leptospira that have been infecting dogs recently, as they are not included in commercial vaccines for dogs.
L. bratislava
L. grippotyphosus
L. pomona
Leptospira is very common in these highly persistent shedders.
Rodents
List some species that serve as carriers of Leptospira
Deer, opossum, raccoons, skunks, foxes, rabbits, swine, cattle
Two forms of Leptospira
Anicteric form (resembles flu)
Icteric form
Which form of Lepotspirosis has clinical signs such as fever, chils, myalgia, stiff neck, and vomiting?
Anicteric form
Which form of Leptospirosis has clinical signs that include aseptic meningitis, jaundice, petichia of skin, renal insufficiency, and hepatomegaly?
Icteric form
How is Leptospirosis diagnosed?
Microscopic agglutination test
Blood culture first week
Urine culture after first week
How may Leptospirosis be controlled?
Proper clothing, personal hygiene, rodent control
Keep rodents out of food prep areas
Proper control of environment and vaccination to control in population
Intracellular agent causing psittacosis
Chlamydiophila psittaci
How is Chlamydiophila psittaci acquired?
Inhalation of airborne agent
Most common reservoirs of Chlamydiophila psittact include...
Parrots, parakeets, love birds, pigeons
Psittacosis poses an ocupational hazard, especially for those working with...
Turkeys
Clinical signs of psittacosis in man
Respiratory illness, cough, chest pain, pharyngitis, pleurisy, pneumonia
Clinical signs of psittacosis in birds
GI signs
Occasionally conjunctivitis, pneumonitis
Treatment for psittacosis includes
Tetracyclines, doxycycline
How can you control the spread of psittacosis?
Avoid aerosolizing bird droppings
Quarantine and treat birds
0.5% chlortetracycline in birds' feed for 45 days
Test birds with elementary body agglutination test for IgM
Chlamydia species affecting sheep.
Chlamydiophila abortus
How is Chlamydiophila abortus transmitted?
Fetal and uterine fluids of infected ewes.
Chlamydiophila abortus may cause what human complication?
Abortion in pregnant women
Which Chlamydiophila is considered a non-human pathogen?
C. felis
Agent responsible for Q fever
Coxiella burnetti
How is Coxiella acquired?
Uterine discharges, urine, feces, milk, wool in slaughter houses, zoo animals, queening cats and kindling rabbits
A sheep veterinarian comes down with a fever, chills, sweating, malaise, fever, and sinus headache. His assistant develops a dry cough, nausea, vomiting, diarrhea, pneumonitis, endocarditis, and splenomegaly. What organism could cause both symptom sets?
Coxiella burnetti
What is the main indicator of Q fever that may be seen in carrier animals?
Abortion in sheep and goats
Most reported tick-borne disease in North America
Lyme disease
Agent responsible for Lyme disease
Borrelia burgdorferi
How is Borrelia burgdorferi transmitted?
Bite of Ixodes scapularis/pacificus
How long must a tick stay attached to a host to transmit Borrelia burgdorferi?
48 hours
Clinical signs of Lyme disease in the dog include...
Arthritis, shifting leg lameness, fever, anorexia, lymphadenopathy, renal disease
Erythema chronicum migrans is a common initial sign of what disease?
Lyme disease
This disease is marked by a non-pruritic erythema, malaise, fever, arthralgia, cephalgia, and myalgia.
Lyme disease
What CNS signs may develop weeks to months after an initial Lyme disease diagnosis?
Meningitis, encephalitis, and facial paralysis
How is Lyme disease treated?
Doxycycline (amoxicillin in children) for 10-30 days
How can Lyme disease be prevented?
Avoid tall grass and dense vegetation
Keep grass short in yards
Wear light colored clothing
Tuck pants into boots and wear long sleeves
Conduct tick checks on yourself, kids, and pets
Apply DEET tick repellent to areas of body that may be exposed to ticks.
List some zoonotic diseases to which AIDS patients are especially susceptible.
Toxoplasmosis
Cryptosporidiosis
Salmonellosis
Rhodococcus
Microsporidiosis
Bartonellosis
Campylobacteriosis
Mycoplasma avium
Toxoplasma is acquired by...
Ingestion of undercooked meats or unwashed produce, in utero, or thru poor hygiene when handling soil or litter containing cat feces
List some sources of a Cryptosporidium infection in humans
Human oral anal contact
Contact with sick calves or cats with crypto
What kinds of animals should an immunosuppressed person avoid?
Immunosuppressed animals
Exotic or wild animals
Stray dogs and cats
Sick animals (especially with diarrhea)
Is it okay for an AIDS patient to have a pet cat? If so, under what circumstances?
Yes, they should just was hands after cleaning litter box or have someone else change the box daily. The cat should also be kept indoors or be belled toprevent hunting.
How great is the health risk if an immunocompromised individual keeps pet birds?
Low risk
Immunocompromised individuals should NOT own these animals.
Reptiles (Salmonella risk)