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49 Cards in this Set
- Front
- Back
Infants require at least __ immunisations to pertussis to stop being at risk of severe disease.
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Infants require at least 2 immunisations to pertussis to stop being at risk of severe disease.
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What is the overall mortality of pertussis in the general population?
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0.03%.
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What is the overall mortality of pertussis in infants?
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3.5%
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How is pertussis usually transmitted?
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Through respiratory droplets.
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What is the approximate incubation period of pertussis?
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10 days.
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When is pertussis most infectious?
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In the first 2 weeks (it gradually decreases).
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How long can the cough of pertussis last?
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It can last up to 3 months.
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What antibiotic options can be used to treat pertussis?
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- Azithromycin.
- Clarithromycin. - Erythromycin. |
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Treatment of pertussis reduces infectivity significantly if taken early enough. How early?
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Within 21 days of general symptoms or 14 days of cough.
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You should suspect cases of pertussis that remains infectious for approximately ___ after treatment commences.
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You should suspect cases of pertussis that remains infectious for approximately 5 days after treatment commences.
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What groups are recommended in having pertussis prophylaxis vaccination?
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- Babies < 12 months regardless of vaccination.
- Child 12-24 months with less than 3 doses of pertussis vaccine. - Any woman in their last month of pregnancy. - Any child or adult who attend or works in childcare. |
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Infectious Disease notification involves....
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Diagnosis (confirmed or provisional).
Information: - Reviewed local public health unit (action taken if required). - Collated and reviewed at the central office (action taken if required). - Collated and reviewed at national level (action taken if required). - International overview by WHO. |
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Why is it important for notification of infectious disease?
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- Immediate action can be taken to prevent secondary transmission. e.g. meningococcal, measles.
- Monitor trends for planning and policy e.g. Ross River Virus, Hep C. - Detect clusters or disease outbreaks. e.g. food-borne disease, hepatitis A. - Knowledge of determinants. - Review of data at local, state, national and international level. |
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What diseases require IMMEDIATE notification?
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- Suspected invasive meningococcal disease.
- Suspected invasive haemophilus B infection. - Dengue fever. - Food/water borne in 2 or more cases. - Haemolytis uraemic syndrome. - Acute flaccid paralysis. - Acute viral hepatitis. - Pertussis. - Suspected measles. - Diptheria. - Legionellellosis. - Lyssavirus. |
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In infants, what non-specific signs may indicate meningococcal meningitis?
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- Fever.
- Irritability. - Poor feeding. - Lethargy. - Vomiting. - Fontanelle may be full. |
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In older children, what symptoms would you look for in possible meningococcal meningitis?
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- Headache.
- Photophobia. |
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What suggestive signs do you look for in meningococcal meningitis?
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- Neck stiffness (unreliable).
- Kernig's sign. - Purpuric/petechial rash suggestive of meningococcal septicaemia. |
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What particular sign should you look out for in complicated meningococcal septicaemia?
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Purpuric/petechial rash.
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What are the steps to take for severe systemic meningococcal infection?
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- Immediate transfer of suspected cases to hospital.
- Administration of benzylpenicillin. - Post-exposure prophylaxis to 'contacts'. |
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How many people are infected by Hepatitis C worlwide?
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350 million infections worldwide.
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How is Hepatitis C transmitted?
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- Transfusion (rare now).
- Reusing injecting equipment. - Non-sterile skin incision procedure. - Sharps injuries. - Mother to baby - approximately 4% of PCR RNA positive mothers will pass on HCV. |
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What percentage of HCV-infected people do not clear the virus and develop chronic Hepatitis C infection?
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65-85%.
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What percentage of HCV-infected people clear the virus and continue to carry Hepatitis C antibodies?
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15-35%.
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What percentage of Hepatitis C patients with chronic infection may never develop obvious signs or symptoms of illness?
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20-40%.
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On average, after 15 years, approximately 40-60% of people with Chronic hepatitis C infection will experience what?
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Some symptoms and develop some liver damage/injury.
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On average, after 20-30 years, approximately 7-16% of people with chronic Hepatitis C will develop what?
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Cirrhosis.
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Approximately 2-5% of people with cirrhosis from hepatitis C will develop what?
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Liver failure or hepatocellular carcinoma.
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What percentage of chronic Hepatitis C infected people are asymptomatic?
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50%.
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What signs, symptoms and investigation signs would you look out for with hepatitis C infection?
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- Lethargy, malaise.
- Right upper abdominal pain. - Liver enzymes fluctuations. - HCV particles in blood. |
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How is hepatitis C infection treated?
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Combination therapy: interferon and ribavirin.
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A sustained response occurs in what percentage of Hepatitis C infected patients using PEG-IFN and RBV?
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90%.
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What is the incubation period of the varicella zoster virus in chicken pox?
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10-21 days.
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What prodromal symptoms typically occur with chicken pox?
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- Fever.
- Lethargy. - Anorexia. |
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What is the pathological course of the lesions associated with chicken pox?
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Crops of papules that become vesicles and then crust over.
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What location is chicken pox lesions usually located?
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It can occur anywhere, but it is most common at:
- Scalp. - Face. - Trunk. - Mouth. - Conjunctiva. |
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How long does it usually take for chicken pox to fully crust over?
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10 days.
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During what periods of the illness is chicken pox infective?
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2 days before rash and until all lesions have crusted over.
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How long should children be excluded from school with the chicken pox?
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At least 5 days after the first eruption.
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At birth, what immunisations are required?
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Hepatitis B only.
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What immunisations are required at 2 months of age?
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- DTPa IPV (combined).
- Hep B and Hib (combined). - Pneumococcal. |
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What immunisations are required at 4 months of age?
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- DTPa IPV (combined).
- Hep B and Hib (combined). - Pneumococcal. |
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What immunisations are required at 6 months of age?
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- DTPa IPV (combined).
- Pneumococcal. |
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What immunisations are required at 1 year of age?
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- MMR.
- Hep B and Hib (combined). - Meningococcal. |
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What immunisations are required at 18 months of age?
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Varicella.
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What immunisations are required at 4 years of age?
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- DTPa IPV (combined).
- MMR. |
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How many times and when is the rotavirus vaccine administered?
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Oral vaccine given in 2-3 doses to infants 6-32 weeks.
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What is the efficacy of the rotavirus vaccine?
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74%.
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Is the rotavirus vaccine funded by medicare?
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It is recommended, but not funded by medicare.
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How many doses of Gardasil are required?
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3 - Day 0, 2 months, 6 months.
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