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11 Cards in this Set

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What is clubbing?
(clinical sign) A condition which describes the broadening or thickening of the tips of the fingers (and toes) with increased lengthwise curvature of the nail and a decrease in the angle normally seen between the cuticle and the fingernail.

Often this finding on physical examination can be quite subtle and easily overlooked. Clubbing may be seen in a wide variety of conditions - most of which result in a decrease in blood oxygen.

Examples include: tetralogy of Fallot, transposition of the great vessels, atrial myxomas, cystic fibrosis, emphysema, lung cancer, tuberculosis, cystic fibrosis, bronchiectasis, Hodgkin's disease, cirrhosis, chronic active hepatitis and Crohn's disease.

This finding will generally provoke a more detailed patient evaluation.
Salycylates cause...
metabolic acidosis
What is metabolic acidosis
A metabolic derangeent of acid-base balance where the blood pH is abnormally low.
___ failure pts are likely to get metabolic acidosis
RENAL
Cardiogenic schock can be caused by
metabolic acidosis
Indications for Hemodialysis:(8)
-RF
-CHF((relative)
Acute lung injury
Persistent CNS disturbances
Progressive deterioration in vital sighs
Severe-acid base or electrolyte imbalance, desite appropriate treatment
Hepatic compromise with coagulopathy
Salycylate level (acute)>100mg/mL
__reduces absorption of therapeutic aspirin doses by 50-80%
AC
THree ways to treat people with salycylic OD
Fluid retention, Alkalinization, gastric decontamination
two diagnostic tests for salicylate
Ferric choloride test

ABG
congenital absence of phenylalanin Hydroxylase
phenylketonuria
What does alkalinizign plasma do?
Alkalinization of the plasma with respect to the tissues and alkalinization of the urine with respect to plasma shifts the equilibrium to the plasma and urine and away from the tissues (including brain). This equilibrium shift has been called “ion trapping.”