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19 Cards in this Set
- Front
- Back
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All class I antidysrhytmics bind to this channel.
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Cardiac voltage-gated fast inward sondium channels(IA, IB, IC)
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What effect do class 1 have on affected channel?
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Slows Na+ channel recovery
-slows xversion form the open or inactivated state to the resting state -Must occur b4 the channel can reopen and begin depolarization again |
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What happen when a class I is bound to several of the affected channels?
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Fewer channels are capable of reactivation upon the arrival of the next depolarizing impulse
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Use of Procainamide?
-Absorption time? |
Used to suppress atrial or ventricular tachdysrhythmias
-Absorption from the GI tract is rapid(may be delayed in OD) |
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IV hyperton NaHCO3 recommended for what ECG patterns?
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Pts with a widening of the QRS complex duration
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Hypokalemia may further prolong the __ interval
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QT
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Treated with rapid saline infusion
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Hypotension
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THis is treated with:
hypertonic NaHCO3 Lidocaine |
Ventricular dystrhythmias
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What class is Lidocaine?
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IB
*may displace the "slower" Class IA gents from the Na+ channel |
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may be useful in treating Torsades de pointes
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Mg Sulfate
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Drugs to avoid in treating Class IA toxicity.
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-Class IA agents
-Class I C agents B-adrenergic antagonists CCB |
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synthetic derivative of cocaine
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Class IB
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What class is Flecainide
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IC
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What are some conditions that can reduce flecainide clearance?(4)
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renal insufficiency
metabolic drug interactions CHF alkauria |
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Pts using therapeutic doses of Flecainide may develop
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Left Vent. dysfunc.
CHF |
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Treatment of Flecanide OD.
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admin of other Class IC or IA(not recommded)
sodium bicarb |
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What class is
AMIODARONE BRETYLIUM |
Class III
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this class prevent and terminate re-entrant dysrhythmias
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Class III
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Side effects of Fecainide?(4)
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Blurred vision
dizziness constipation chest pain |
