Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
26 Cards in this Set
- Front
- Back
- 3rd side (hint)
|
Pathology
|
Study of disease (cell & tissue changes)
|
|
|
|
Pathophysiology
|
Study of functional or physiologic changes in the body the result from processes (disease)
|
|
|
|
Etiology (cause of disease)
|
Concerns the causative factors in a particular disease.
Burns, malignancy, microorganisms, genetic disorders, congenital defects |
Idiopathic when unknown
|
|
|
6 Key Terms
|
Homeostasis
Symptoms Signs Etiology Diagnosis Prognosis |
|
|
|
Cell Damage (Causes)
|
T.I.P.D. Toxins, Infection, physical injury, deficit (0xy)
|
|
|
|
4 Types of cell damage
|
Necrosis- dead
Infarction- dead Ischemia- reversible Gangrene- Bacteria & dead |
|
|
|
4 Primary systems of PT
|
Musculoskeletal- bones, joint, muscle
Neurological- brain/nerve inflamm Cardiopulmonary/ Respiratory Integumemtary- burns, ulcers |
|
|
|
2 types of Non-specific process
|
Mechanical- skin, mucus, secretions
Non-mechanical- phagocytosis, Inflammation |
|
|
|
Specific process
|
Immune system
|
|
|
|
Inflammation serves as a _________ to the body
|
Warning/sign. localize & remove agents
|
|
|
|
Vascular Response to Inflamm
|
1) rapid release of chemical mediators (histamine, prostaglandin)
2) Local vasodilation 3) Increased blood flow 4) Increase in capillary Permeability 5) Shift of Plasma proteins into interstitial spaces |
|
|
|
Chemical Response to Inflammation
|
1) Leukocytes respond
2) Nuetrophils, monocytes, macrophages = phagocytosis 3) Lysosomal enzymes are released 4) Damage nearby cells & prolong inflammation |
|
|
|
Complications of inflammation
|
Decrease BF, nutrients, removal of waste, fluid shift Out of capillary
Increase pain |
|
|
|
Local effects of inflammation
|
(R.E.P.F)
Redness Edema Pain Loss of Function |
|
|
|
Chronic inflammation
|
Less swelling
More Lymphocytes, macrophages, fibroblasts More collagen More fibrous scar tissue formation Persistent pain cycle Functional loss |
|
|
|
Persistent pain cycle
|
Tight muscles> reduced circulation> increased pain
|
|
|
|
Infection 2 types of secretions
|
Bacterial: exudate or pus
Viral: serous exudate (Clear) |
|
|
|
Resolution Healing
|
Minimal tissue damage (cell recover back to normal) 1st degree burn
|
|
|
|
Replacement or repair healing
|
scar or fibrous tissue formation
cells incapable of mitosis -infection -chronic inflammation |
|
|
|
Regeneration Healing
|
cells are capable of mitosis
proliferation by nearby cells |
|
|
|
keloid formation
|
abnormality in healing by scar tissue
-tumor like mass due to excessive production of collagen/scar tissue |
|
|
|
Acute inflammation
|
Cells & platelets release chemical mediators into blood & interstitial fluid
|
|
|
|
Prognosis
|
probability for recovery (average)
|
|
|
|
|
|
|
|
3 types of healing
|
resolution
regeneration replacement |
|
|
|
medical management of inflammation
|
Asprin
NSAIDS Glucocorticoids |
|
