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6 Cards in this Set
- Front
- Back
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Structure of natriuretic peptides
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cyclic peptides
cyclic from oxidation of Cysteine side chains Only active when cyclic |
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ANP
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28aa
main site of production is cardia atria |
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CNP
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22aa,
made in brain>>kidney, vas endo |
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NPs
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Enhance sodium excretion
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BNP precursor
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pro-protein is 108aa, then mature 32aa piece is from c-term
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Metabolism of NP
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GF
extracellular hydrolysis 3.if bind to receptor C get internoalized and then degraded |
