Psychopharmacotherapy-Case Files

Front 1

Increasing the level of monoamines in the synapse by reducing the reuptake of NE and serotonin.

Back 1

Tricyclics and Heterocyclics

Front 2

Most commonly used antidepressants. Major side effects include GI and sexual dysfunction.

Back 2

SSRI

Front 3

What diet must be followed with MAOI's?

Back 3

Tyramine free diet (no wine or cheese)

Front 4

Overdose of what antidepressant causes fatal cardiac arrythmias?

Back 4

Tricyclics and Heterocyclics

Front 5

What antidepressants are more helpful in depression with atypical features (overeating, oversleeping, irritability)

Back 5

MAOIs

Front 6

Block the reuptake of serotonin by the presynaptic neuron (top), allowing more serotonin to be available at the postsynaptic receptor.

Back 6

SSRI

Front 7

Block the ability of this enzyme to inactivate monoamines such as NE in the synaptic cleft allowing more neurotransmitter to bind to the postsynaptic receptor.

Back 7

MAOIs

Front 8

Amitriptyline

Back 8

TCA

Front 9

Doxepin

Back 9

TCA

Front 10

Imipramine

Back 10

TCA

Front 11

Trimipramine

Back 11

TCA

Front 12

Desipramine

Back 12

TCA

Front 13

Nortriptyline

Back 13

TCA

Front 14

Protriptyline

Back 14

TCA

Front 15

Amoxapine

Back 15

TCA

Front 16

Fluoxetine

Back 16

SSRI

Front 17

Sertraline

Back 17

SSRI

Front 18

Paroxetine

Back 18

SSRI

Front 19

Fluvoxamine

Back 19

SSRI

Front 20

Citalopram

Back 20

SSRI

Front 21

Escitalopram

Back 21

SSRI

Front 22

Phenelzine

Back 22

MAOI

Front 23

Tranylcypromine

Back 23

MAOI

Front 24

Venlafaxine

Back 24

Miscellaneous

Front 25

Nefazodone

Back 25

Miscellaneous

Front 26

Trazodone

Back 26

Miscellaneous

Front 27

Mirtazapine

Back 27

Miscellaneous

Front 28

Bupropion

Back 28

Miscellaneous

Front 29

Lithium

Back 29

Mood Stablizier

Front 30

Valproic Acid

Back 30

Mood Stabilizer

Front 31

Carbamazepine

Back 31

Mood Stabilizer

Front 32

Lamotrigine

Back 32

Mood Stabilizer

Front 33

Gabapentin

Back 33

Mood Stabilizer

Front 34

TCA: Least anticholinergic, not sedating

Back 34

Desipramine

Front 35

TCA: EPS

Back 35

Amoxapine

Front 36

SSRI: More diarrhea

Back 36

Sertraline

Front 37

SSRI: Mildly anticholinergic

Back 37

Paroxetine

Front 38

SSRI; N/V more common

Back 38

Fluvoxamine

Front 39

SSRI: Fewer sexual side effects

Back 39

Citalopram

Front 40

Venlafaxine

Back 40

Serotonin and NE reuptake inhibitor

Front 41

Nefazodone, Trazodone

Back 41

Serotonin-2 antagonist and serotonin reuptake inhibitor

Front 42

Priapism: prolonged erection may lead to impotence

Back 42

Trazodone

Front 43

Mirtazapine

Back 43

Noradrenergic and specific serotonin antagonist

Front 44

Bupropion

Back 44

NE reuptake inhibitor and dopamine reuptake inhibitor

Front 45

Used for smoking cessation. Contraindicated in patients with an eating disorder or a seizure disorder.

Back 45

Bupropion

Front 46

Lithium

Back 46

Inhibits adenylate cyclase

Front 47

What tests must be done with Lithium?

Back 47

1.Serum Lithium Levels
2.Renal Function Tests
3.Thyroid Function Tests

Front 48

Valproic Acid

Back 48

Opens chloride channels, unknown

Front 49

Main side effect of valproic acid in pregnancy?

Back 49

Neural Tube Defects

Front 50

What 2 mood stabilizers must be used in caution in women of childbearing age?

Back 50

Lithium
Valproic Acid
BOTH teratogenic

Front 51

Carbamazepine

Back 51

Inhibits kindling, inhibits repetitive firing of action potentials by inactivating sodium channels.

Front 52

Craniofacial defects in newborn

Back 52

Carbamazepine

Front 53

Mood stabilizer that is a potent stabilizer of P450 system.

Back 53

Carbamazepine

Front 54

Side effect of lamotrigine.

Back 54

Somnolence, dizziness

Front 55

Alternative choice, may have acute antidepressant effect; dose must be increased slowly to avoid rash

Back 55

Lamotrigine

Front 56

Rash can be fatal.

Back 56

Gabapentin

Front 57

Side effect is diabetes insipidus.

Back 57

Lithium

Front 58

Chlorpromazine

Back 58

First Generation Antipsychotic Agent

Front 59

Haloperidol

Back 59

First Generation Antipsychotic Agent

Front 60

Thioridazine

Back 60

First Generation Antipsychotic Agent

Front 61

Mesoridazine

Back 61

First Generation Antipsychotic Agent

Front 62

Molindone

Back 62

First Generation Antipsychotic Agent

Front 63

Fluphenazine

Back 63

First Generation Antipsychotic Agent

Front 64

Trifluoperazine

Back 64

First Generation Antipsychotic Agent

Front 65

Thiothixene

Back 65

First Generation Antipsychotic Agent

Front 66

Perphenazine

Back 66

First Generation Antipsychotic Agent

Front 67

Loxapine

Back 67

First Generation Antipsychotic Agent

Front 68

Pimozide

Back 68

First Generation Antipsychotic Agent

Front 69

Clozapine

Back 69

Second Generation Antipsychotic Agent

Front 70

Risperidone

Back 70

Second Generation Antipsychotic Agent

Front 71

Olanzapine

Back 71

Second Generation Antipsychotic Agent

Front 72

Quetiapine

Back 72

Second Generation Antipsychotic Agent

Front 73

Ziprasidone

Back 73

Second Generation Antipsychotic Agent

Front 74

Aripiprazole

Back 74

Second Generation Antipsychotic Agent

Front 75

Antipsychotic: Sedation and orthostatic hypotension are very common.

Back 75

Chlorpromazine

Front 76

Antipsychotic: EPS very common

Back 76

Haloperidol

Front 77

Antipsychotic: Higher incidence of cardiac disturbances, retinitis pigmentosa

Back 77

Thioridazine

Front 78

Antipsychotic: Cardiac arrhythmias (torsade de pointe)

Back 78

Mesoridazine

Front 79

Clozapine

Back 79

Agranulocytosis

Front 80

Risperidone

Back 80

Present in breast milk

Front 81

Olanzapine

Back 81

Somnolence

Front 82

Ziprasidone

Back 82

QT interval prolongation

Front 83

Anxiolytic for generalized anxiety

Back 83

Buspirone

Front 84

Anxiolytic for insomia

Back 84

Zolpidem, zaleplon

Front 85

What anxiolytic? Less useful in patients who have used benzo, should not be used with MAOIs.

Back 85

Buspirone

Front 86

What anxiolytic? Increased effect with alcohol or selective SSRIs.

Back 86

Zolpidem

Front 87

Anticholinergic agents used to treat dystonias caused by the use of antipsychotic medications

Back 87

Benztropine, Biperiden, Diphenhydramine, Trihexyphenidyl

Front 88

Meds used to treat akathisias (restlessness caused by the use of antipsychotic medication)

Back 88

Propanolol and Benzodiazepines

Front 89

Meds used to treat Parkinsonian side effects

Back 89

Amantadine
Levodopa