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101 Cards in this Set
- Front
- Back
Pregabalen
|
Lyrica- Mood stabilizer, pain
alpha delta 2 ligand, VSCC |
|
Lorazepam
|
Ativan- anxiolytic, benzo
|
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Modafinil
|
Provigil- Narcolepsy
|
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Eszopiclone
|
Lunesta- hypnotic, non-benzo GABA agonist
|
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Trihexyphenidyl
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Artane- anticholinergic
|
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Oxcarbazepine
|
Trileptal- mood stabilizer, VSSC
|
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Amphetamine, D.L
|
Adderall- ADHD, stimulant
|
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Diphenyhydramine
|
Benadryl- hypnotic; anticholinergic
antihistimine |
|
Triazolam
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Halcion- hypnotic; benzo
|
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Nortriptyline
|
Pamelor- antidepressant; TCA
|
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Clomipramine
|
Anafranil- antidepressant, TCA
|
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Galantamine
|
Razadyne- Alzheimer's; acetylcholinesterase inhibitor
|
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Tranylcypromine
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Parnate- antidepressant; MAOI
|
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Selegine
|
EMSAM- Depression/Parkinson's; MAOI
|
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SARI's
|
Serotonin Antagonist and Reuptake Inhibitors
Etoperidone, Trazodone, Lubazodone, Nefazodone |
|
Mirtazapine
|
Remeron; TeCA antidepressant
alpha 2 antagonist as SNDI |
|
NDRI's
|
Norepinephrine & Dopamine Reuptake Inhibitor
Bupropion |
|
Atomoxetine
|
Strattera: NRI
|
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Buproprion
|
Wellbutrin/Zyban
NDRI antidepressant |
|
Milnacipran
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Ixel- antidepressant; SNRI
|
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Atomoxetine
|
Strattera- NRI's
|
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Bupropion
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Wellbutrin/Zyban- NDRI antidepressant
(activating effects) |
|
Duloxetine
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Cymbalta- antidepressant; SNRI
|
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Milnacipran
|
Ixel- antidepressant; SNRI
|
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Desvenlafaxine
|
Pristiq- antidepressant; SNRI
|
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Venlafaxine
|
Effexor- antidepressant; SNRI
|
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SNRI's
|
Serotonin-Norepinephreine Reuptake Inhibitor
Venlafaxine, Desvenlafaxine, Duloxetine, Milnacipran |
|
Escitalopram
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Lexapro- antidepressant; SSRI
|
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Citalopram
|
Celexa- antidepressant; SSRI
|
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Fluvoxamine
|
Luvox- antidepressant; SSRI
|
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Paroxetine
|
Paxil- antidepressant; SSRI
|
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Mesocortical system (schizophrenia)
|
1.) ventral tegmental area -> DLPFC
2.) Negative sx, cognitive sx |
|
Mesocortical system (schizophrenia) #2
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1.) ventral tegmental area -> VMPFC
2.) Negative sx, affective sx |
|
Mesolimbic system (schizophrenia)
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Positive sx
|
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Sertraline
|
Zoloft- antidepressant; SSRI
|
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Fluoxetine
|
Prozac- antidepressant; SSRI
|
|
SSRI's
|
Selective Serotonin Reuptake Inhibitors
Fluoxetine,sertraline, paroxetine, fluvoxamine, citalopram, escitalopram |
|
Agitation
|
Striatum
Serotonin; Dopamine |
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Distractibility
|
DLPFC
Norepinephrine; Dopamine |
|
Decreased need for sleep
|
Basal forebrain, thalamus, hypothalamus
serotonin; dopamine; norepinephrine |
|
grandiosity; flight of ideas, etc.
|
DLPFC, NA, VMPFC, OFC
serotonin; dopamine; norepinephrine |
|
weight/ appetite change
|
Hypothalamus
serotonin |
|
Psychomotor symptoms
|
Striatum, NA, PFC, Cerebellum
Norepinephrine; dopamine |
|
Executive dysfunction
|
DLPFC
norepinephrine; dopamine |
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Sleep disturbances
|
Hypothalamus, thalamus, PFC, basal forebrain
serotonin; norepinephrine; dopamine |
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Apathy
|
VMPFC; DLPFC
Hypothalamus NA Norepinephrine; dopamine |
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Clorazepate
|
Tranxene
anxiolytic benzo |
|
Oxazepam
|
Serax
anxiolytic benzo |
|
Ramelteon
|
Rozerem
hypnotic melatonin agonist |
|
Rivastigmine
|
Exelon
Alzheimer's acetylchonlinesterase inhibitor |
|
Levetiracetam
|
Keppra
mood stabilizer synaptic vesicle protein modulator |
|
Lamotrigine
|
Lamictal
mood stabilizer VSSC |
|
Suicidal ideation
|
Amygdala
VMPFC OFC serotonin |
|
Depressed Mood
|
inefficient info processing in amygdala
VMPFC ACC serotonin; dopamine; norepinephrine |
|
guilt/worthlessness
|
amygdala
VMPFC serotonin |
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Elevated/irritable mood
|
VMPFC
OFC amygdala serotonin; norepinephrine; dopamine |
|
Alprazolam
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Xanax
anxiolytic benzo |
|
Clonazepam
|
Klonopin
anxiolytic benzo |
|
Topiramate
|
Topamax
mood stabilizer VSSC |
|
Amphetamine D
|
Dexedrine
ADHD stimulant |
|
Donepezil
|
Aricept
Alzheimer's acetylcholinesterase inhibitor |
|
Memantine
|
Namend
Alzheimer's NMDA antagonist |
|
Methylphenidate
|
Focalin
ADHA stimulant |
|
Carbamazepine
|
Tegretol
mood stabilizer VSSC |
|
Gabapentin
|
Neurontin
mood stabilizer; pain Alpha delta 2 ligand; VSCC |
|
Phenlzine
|
Nardil
antidepressant MAOI |
|
Doxepin
|
Sinequin
antidepressant TCA |
|
Trazodone
|
Desyrel
antidepressant SARI |
|
Hydroxyzine
|
Vistaril
hypnotic antihistimine |
|
Benzotropine
|
Cogentin
anticholinergic |
|
Temazepam
|
Restoril
hypnotic benzo |
|
Zolpidem
|
Ambien
hypnotic non-benzo GABA agonist |
|
Lithium
|
Eskalith
mood stabilizer tyrosine kinase |
|
Amitryptyline
|
Elavil
antidepressant TCA |
|
Anticholinergic (2 types)
|
antimuscarinic
antinicotinic |
|
chlordiazepoxide
|
Librium
anxiolytic benzo |
|
Buspirone
|
Buspar
anxiolytic serotonin 1A agonist |
|
Valproic Acid
|
Depakote
mood stabilizer VSSC |
|
Diazepam
|
Valium
anxiolytic benzo |
|
Trifluoperzine
|
Stelezine
conventional antipsychotic |
|
Pimozide
|
Orap
conventional antipsychotic |
|
Lurasidone
|
Latuda
atypical antipsychotic |
|
Iloperidone
|
Fanapt
atypical antipsychotic |
|
Perphenazine
|
Trilafon
conventional antipsychotic |
|
Aripiprazole
|
Abilify
atypical antipsychotic |
|
Thiothixene
|
Navane
conventional antipsychotic |
|
Haloperidol
|
Haldol
conventional antipsychotic |
|
Paliperidone
|
Invega
atypical antipsychotic |
|
Quetiapine
|
Seroquel
atypical antipsychotic |
|
Ziprasidone
|
Geodone
atypical antipsychotic |
|
Loxapine
|
Loxitane
conventional antipsychotic |
|
Chlorpromazine
|
Thorazine
conventional antipsychotic |
|
Asenapine
|
Saphris
atypical antipsychotic |
|
Risperidone
|
Risperdal
atypical antipsychotic |
|
Olanzapine
|
Zyprexa
atypical antipsychotic |
|
Clozapine
|
Clozaril
atypical antipsychotic |
|
What makes an antipsychotic atypical?
|
serotonin 2A antagonism
rapid dissociation from D2 receptors |
|
Fluphenzine
|
Prolixin
conventional antipsychotic |
|
Atypical antipsychotics
|
Low EPS, good for negative symptoms
|
|
What makes an antipsychotic conventional?
|
D2 receptor antagonism
|
|
neurodegenerative hypothesis of schizophrenia
|
Diabolical learning; structural changes
progressive loss of neuronal function via abnormal apoptosis, etc |