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48 Cards in this Set

  • Front
  • Back
Effects of long infant deprivation:

Reactive attachment disorder
Weak, wordless, wanting, and wary.

Decreased muscle tone, poor language skills, poor socialization, lack of trust, anaclitic depression, weight loss, physical illness, and even death.
Anaclitic depression
Depression in an infant owing to continued separation from caregiver. Infant becomes withdrawn and unresponsive.
Rett disorder
X linked DOMINANT; only seen in females (males die in utero).

Xq28, MECP2 gene, usually a denovo mutation.

Loss of milestones and mental retardation beginning at age 4. There can be characteristic hand wringing stereotypy.
Conduct disorder, antisocial personality disorder, and opposition defiant disorder.
ODD is noncompliance in absence of criminality.

Conduct disorder is continued behavior VIOLATING SOCIAL NORMS (criminality).

Antisocial personality disorder is basically conduct disorder at >18 years of age.
Tourette's, and its treatment
Disorder associated with mutation on Chromosome 18, causes involuntary motor/vocal tics.

Treatment includes haloperidol.
Who is the abuser?

Child abuse (3000 deaths per year)

Sexual abuse (peak incidence 9-12 yo)
Child abuse: usually female and the primary caregiver.

Sexual abuse: known to victim, usually male.
Anosognosia
unawareness of illness
Autotopagnosia
unable to locate one's body parts
Depersonalization
body seems unreal or dissociated
Does patient with delirium have a normal or abnormal EEG?
Abnormal EEG.
Dementia
Impairment in MORE THAN ONE cognitive area with impaired ability to FUNCTION. No change in level of consciousness.

EEG is normal, characteristically.
Alzheimers: male>female or female>male ?
Females > Males
Idea of reference
false belief of being referred to by others (e.g. "The news anchor is always talking about me...")

Not narcissism
Hallucination associations:

Visual/auditory
Olfactory
Formication
V/A - schizophrenia

Olfactory - aura of psychomotor epilepsy

Formication - DTs and cocaine abuse
How long do you have to have periods of psychosis and disturbed behavior with decline in functioning for:

Brief psychotic disorder
Schizophreniform disorder
Schizophrenia
<1 month brief

1-6 month schizophreniform

>6 month schizophrenia
Inheritance of schizophrenia (?)

Risk if 1st degree, risk if both parents?
Risk is 10% if first degree relative has it.

Risk is 40% if both parents have it.
Hypomanic episodes: can they have psychotic features?
No, can't have psychotic features in hypomania.
Manic episode
At least 1 week of 3 or more of: DIG FAAST

distractibility, irresponsibility, grandiosity, flight of ideas, agitation, increased activity, decreased need for sleep, talkativeness or pressured speech.
Bipolar
1 manic or hypomanic episode defines bipolar disorder

1% lifetime risk, male = female
20% risk if 1st degree relative has disorder
60% risk if both parents have it
Cyclothymia
dysthymia and hypomania lasting at least 2 years
Depression
Females(10-25%)>>Males(5-12%)

At least 5 of SIGEMCAPS for 2 weeks

Sleep disturbance
Interest
Guilt
Energy
Mood
Concentration
Appetite
Psychomotor retardation or agitation
Suicide
Atypical features of depression
Hypersomnia, hyperphagia, leaden paralysis
Dexamethasone suppression test and depression
50% of patients with depression have no response to dexamethasone suppression tests (!)
Risk factors for completing suicide
Male, Age, Depression, Previous attempt, Ethanol/drugs, loss of Rational thinking, Sickness, Organized plan, No spouse, Social support lacking
Also: history of rage/violence

Men are 4x more likely to succeed, women 3x more likely to try.
Sleep patterns in depression
Decreased slow wave sleep, decreased REM latency, increased REM early in sleep cycle, increased REM sleep, repeated night time awakenings

Early morning awakening is one of the most important things
Postpartum reactions
Blues: 33-50% of mothers; sad, tearful, normal grooming, lasting up to two weeks post delivery.

MDD: 5-10% of mothers; poor grooming, typical depressed signs, begins usually 4 weeks postpartum

Psychosis: .1-.2%; hallucinations, delusions, no depression; begins usually 2-3 weeks postpartum.
Fear versus anxiety
fear - normal reaction to known source of danger

anxiety - unknown or inadequate source of danger
Organic causes of anxiety
excessive caffeine
substance abuse
B12 deficiency
hyperthyroidism
hypoglycemia
anemia
arrhythmia
pulmonary disease
pheochromocytoma
Algophobia
fear of pain
Acrophobia
fear of heights
PTSD
lasting greater than 1 month and causing impairment

intense fear, helplessness, horror, avoidance of stimuli associated with trauma, guilt, dissociativeness

Often follows acute stress disorder
Adjustment disorder
Emotional symptoms causing impairment following an identifiable psychosocial stressor and lasting <6 months.
Generalized anxiety disorder
uncontrollable anxiety for at least 6 months

that is not related to anything specific

there can be associated sleep disturbance, fatigue, difficulty concentrating
Malingering
faking to attain a gain, aside from attention

avoids treatments
Factitiious disorder
consciously creates symptoms in order to assume sick role and get attention. Classic grid abdomen.

Munchausen's syndrome

Munchausen's by proxy: child abuse
Somatoform disorders
patients truly believe they're ill

"physical symptoms without organic cause"

-conversion disorder
-somatiform pain disorder
-hypochondriasis
-somatization
-body dysmorphic disorder
-pseudocyesis - false pregnancy
Cluster A personality disorders
"Peculiar"

Paranoid

Schizoid - social withdrawal but content with it, limited emotion

Schizotypal - awkward, odd, magical thinking, eccentric
Depersonalization disorder
Persistent and recurrent feelings of detachment from one's body, social situation, or environment.
Cluster B personality disorders
"Dramatic, erratic"

- Antisocial (increased ETOH, ADHD, criminality)

- Borderline - splitting, impulive, unstable (increased risk of MDD, substances)

- Histrionic - excessive emotionality, attention seeking, sexually provocative (increased risk of somatization)

- Narcissistic - grandiosity, entitlement, react to criticism with rage
Cluster C personality disorders
"Anxious, fearful"

Avoidant - sensitive to rejection, socially inhibited, timid, inadequacy

Obsessive compulsive - preoccupation with order, perfectionism, control

Dependent - submissive, clinging, excessive need to be taken care of
Mood in anorexia and bulimia
Anorectics tend to have normal mood

Bulimics tend to have depression, especially post binge.

Bulimics can get varices, by the way.
GGT
sensitive indicator of alcohol use, increases within hours of use
cotinine
a nicotine metabolite that is excreted in urine, lasts for 1-2 days after last cigarette
benzoylecgonine
a cocaine metabolite that lasts for 1-12 days, depending on use
SGOT and CPK increases, lasting for >7days
indicates PCP use

also, belligerence, fever, agitation, nystagmus, homicidality, psychosis, ataxia, tachycardia
Mechanism of fatty liver
Ethanol --> acetaldehyde --> acetyl-CoA --> increased fatty acid synthesis --> fatty liver
Alcoholic cirrhosis: macro or micronodular?
micronodular

macronodular results from major insults with gross necrosis
Mallory Weiss tears
lacerations at the GEJ caused by excessive vomiting, associated with pain, unlike varices