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48 Cards in this Set

  • Front
  • Back
Investigations before starting Lithium. (4 sets)
Ht & Wt
FBC, U&E + creatinine, TFTs
ECG
Pregnancy Test
Lithium monitoring of serum levels
1wk after starting then weekly till 4 stable readings

3monthly serum levels
Thyroid and Renal tests every...
6 months (U&E), 12months (TFTs)
3 Drug classes to be avoided with lithium
ACEi, Diuretics, NSAIDs
Valproate unusual SE
Wt and appetite gain
Sedation
Ankle swelling
Hair Loss
Carbamazepine unusual SEs
Skin rashes
Blurred vision
Ataxia
SSRI SEs (3)
WISGAS

Wt Loss
Insomnia
Sexual Dysfunction
GI disturbance
Anxiety (shrt)
Sweating
Atypical Antipsychotic SEs
Wt gain
Postural hypotension
EP SE's (less than typical)
Diabetes
Neuroleptic Malignant Syndrome rare
Typical Antipsychotic SEs
EP SE's tardive dyskinesia, parkinsonian, akasthesia, dystonia.
Galactorrhea
Cardiovascular
Antimuscarinic
Definition of a delusion
Pathalogical belief
Held with absolute certainty when challenged
Cannot be understood as part of cultural/religious background
Section 5.2
Doctor
Inpatient
72hrs
Section 5.4
Nurse
6hrs
Section 136
Police
Suicide risk factors
SAD PERSONS

Sex, Age, Depression
Previous, Ethanol, Rational, Social support, Organised plan, No hobbies
Catatonic rigidity
Maintaining a fixed position and rigidly resisting attempts to be moved
Catatonic posturing
Adopting an unusual or bizarre position that is then maintained for some time
Catatonic negativism
A seemingly motiveless resistance to all instructions or attempts to be moved; patients may do the opposite to what is asked
Catatonic waxy flexibility
Patients can be moulded like wax
Catatonic excitement
Agitated, excited and seemingly purposeless motor activity, not influenced by external stimuli
Catatonic Stupor (3)
akinesis (lack of voluntary movement),
mutism
extreme unresponsiveness in an otherwise alert patient.
Echopraxia
Patients senselessly repeat or imitate the actions of those around
Echolalia
Repeat speech
Mannerisms
Apparently goal-directed movement but at inappropriate time
Stereotypies
Complex movement that is not goal-directed
Cotard's Syndrome
Hypochondriacal delusions
Nihilistic delusions
As part of depressive psychosis (elderly)
Delusion of reference
False belief that certain objects, people or events have intense personal significance (TV)
Clerambault syndrome
Woman believes a man, frequently older and of higher status, is in love with her
Othello syndrome
False belief that one's lover has been unfaithful
Ekbom's syndrome
Delusion of infestation
Agnosia
inability to recognise objects
Features of Cortical dementia (4)
Aphasia
Apraxia
Agnosia
Calculation
Features of Sub-cortical dementia (3)
Dysarthric
Stooped posture
Tremor, tics
Schizoid personality disorder
L Dad
Emotional coldness
Neither enjoy nor desires close sexual relationships
solitary activity
pleasure in few activities
indifferent to praise/criticism
Schizotypal personality disorder
L
Eccentric behaviour
Odd beliefs or magical thinking
unusual perceptual experiences
ideas of reference
suspicious or paranoid ideas
vague circumstantial thinking
social withdrawal
Anankastic Personality disorder
OCD
Perfectionism and control
Devoted to work at expense of leisure
Pedantic rigid and stubborn
Cautious
Borderline (emotionally unstable) personality disorder
Unstable
Relationships
Unstable self-image
Inpulsivity
Self-harm
Avoid abandonment
Acamprosate

Use and MOA
Reduce likelihood of relapse
(craving dec)
Increases GABA
Disulfiram

Use and MOA
Relapse prevention : Choking, Headache, Flush
Alcohol oxidation inhibitor
2 drugs acute treatment of alcohol withdrawl
Benzo (chlordiazepoxide) to reduce seizure risk
Thiamine (Wernicke's)
2 Opiate substitution drugs
Methadone
Buprenorphine (partial)
2 receptor antagonists that can precipitate severe withdrawl
Naltrexone (opiate antag) used to block euphoria in ex-toxics
Flumazenil (benzo antag) used to differentiate loss of consciousness is due to benzo
Lofexidine

Use
MoA
Centrally cating alpha agonist
Reduce symptoms of Opiate withdrawl
Buprenorphine

Use
MoA
Partial opiate agonist
Step down reduction drug
Russel's sign
Calluses on the back of hands from repeated teeth trauma in Bulimia
Trazadone

MoA
Use
5HT2 re-uptake blocker
antidepressant
Sedative property
Venlafaxine

MoA
Use
SNRI
like TCA but less Acetylcholine and histamine blockade.
Mirtazapine

MoA
NaSSA
Nefazodone
SARI
potentiates 5HT
but blocks 5HT-2A