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20 Cards in this Set

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Major soutces of


1. Serotonin


2. Norepinephrine


3. Acetylcholine


4. Dopamine

1. Midline raphe nucleus


2. Locus ceruleus


3. Nucleus basalis and nucleus of Meynert


4. Substantia nigra

Papez circuit

@ MATCH


M: mamillary bodies


A: anterior


T: thalamic nuclei


C: cingulate gyrus


H: hippocampus

Phineas Gage

Railway worker ( injury to frontal lobes , esp left)


✓impulsive


✓profanity


✓disinhibited


✓aggressive

Formal thought disorder


1. Transitory thinking


2. Drivelling thinking


3. Desultory thinking

1. Problem of constancy


2. Problem of organisation


3. Problem of continuity

1. Mc type of hallucination


2. Mc hallucination a/w functional disorders


3. Mc hallucination a/w organic mental disorders

1. Auditory


2. Auditory


3. Visual

1. Autoscopy


2. Heautoscopy


3. Internal autoscopy


4. Negative autoscopy


5. Positive autoscopy

1. Aka out of body experience ( OBE) , pt can see self from outside


2. Pt can see a real self and imaginary self


3. Pt can see internal organs, parts of body


4. Inability to see reflection in mirror


5. Somebody else's reflection is seen in mirror

Levels of insight

6


1. Denial


2. Ambivalence


3. Acceptance- physical


4. Acceptance - self


5. Intellectual insight : increased chance of relapse


6. Emotional insight: highest level of insight

Emotions


1. Generated in


2. Controlled by

1. Limbic system


2. Frontal lobe

Body types and susceptibility to ?

A: asthenic ( thin and weak ) : more susceptible to schizophrenia



B: athletic ( muscular)



C: pyknic ( short and fat ) : more susceptible to bipolar disorder

1. Logoclonia


2. Palilalia

1. Last syllable of last word is repeated


2. Pt repeats perseverated word with increasing frequency

Schizophrenia with


1. Best prognosis


2. Worst prognosis

1. Catatonic


2. Simple

Clozapine


1. Benefit


2. Side effects


3. Mc side effect

1. Useful in treatment resistant schizophrenia ; antisuicide property


2. Agranulocytosis, myocarditis and seizures


3. Sedation

Antipsychotic causing


1. Mydriasis


2. Miosis


3. Impotence


4. Impaired ejaculation

1. Thioridazine


2. Chlorpromazine ( also causes urinary retention and orthostatic hypotension)


3. Chlorpromazine


4. Thioridazine

Typical antipsychotics with


1. Low potency


2. High potency

1. Chlorpromazine, thioridazine


2. Haloperidol, fluphenazine

1. Earliest side effect of first generation antipsychotics


2. Mc side effect of first gen antipsychotics

1. Acute dystonia


( Seen in young males)


2. Acute akathisia

Pathophysiology of neuroleptic malignant Syndrome

✓ D2 blockade in


1. Corpus striatum: muscle rigidity


2. Hypothalamus: fever


3. Spinal neurons: autonomic disturbances


4. High CPK d/t muscle rigidity


5. Myoglobinuria, renal failure


1. mc psychiatric disorder


2. Second mc

1. Specific phobias


2. Depression

Kleine levin Syndrome

Aka sleeping beauty syndrome


- Hypersomnia

Biochemical abnormalities in schizophrenia

Increase in dopamine


Increase in serotonin

In ICD -10 which letter is used to denote mental illness

F