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28 Cards in this Set
- Front
- Back
TCAs
overview |
•Can be lethal in overdose
•Can have a 3-4 week delay before therapeutic response. •No known long term adverse effects. •Persistent side effects can often be minimized by a small decrease in dose. •Do NOT cause physical addiction. •Do NOT cause euphoria, so they have no abuse potential. •Can be conveniently given once a day. |
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TCAs -Side effects
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Most side effects are short-term.
•Sedation •Increased appetite •Anticholinergic side effects •Orthostatic hypotension •Not usually given for patients with history of heart problems, due to possibility of tachycardia, arrhythmia, or heart block. |
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MAO-Is
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•Very effective medications
•Can be lethal in overdose |
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MAO-Is
•Side effects: |
•anticholinergic
•cardiovascular: hypotension most common •Careful patient teaching is absolutely necessary. •Interaction with tyramine-containing foods or drugs can cause hypertensive crisis. •Bad drug interactions: SSRIs, Demerol |
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Hypertensive Crisis
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•Sudden increase in BP
•Explosive headache •Head and face are flushed, feel “full” •Stiff neck •Palpitations, chest pain •Nausea, vomiting •Dilated pupils •Intracranial bleeding •Heart attack |
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If hypertensive crisis occurs:
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•Hold next MAO-I dose.
•Do not have patient lie down. •IM chlorpromazine (Thorazine) •Manage fever by cooling patient externally. |
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MAO-I -Dietary Restrictions:
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1 day before, during, and 2 weeks after taking:
Foods to avoid include: •Cheese, sour cream, yogurt •Pickled, dried, fermented, smoked or aged fish or meats •Beer, wine, sherry, liqueurs, cognac •Liver •Overripe fruit •Yeast •Chocolate •Caffeine |
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MAO-I: Avoid these:
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•Narcotics, especially DEMEROL
•Other antidepressants! •Cold, allergy or hay fever meds •Weight-reducing pills or stimulants •Cocaine, amphetamines |
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SSRIs
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•Relatively safe in overdose
•Treatment effects comparable to other antidepressants, but withoutsignificant anticholinergic, cardiovascular or sedative side effects. •Prozac -what’s the story -before depression gets better, energy increased |
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SSRIs -Side Effects
Reported by some patients: . |
•GI symptoms:
–Nausea, diarrhea, decreased appetite •CNS symptoms: –Headache, dizziness, nervousness, sexual dysfunction. –SSRIs generally do not cause sedation or weight gain |
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Serotonin Syndrome
•overview |
Caused when combinations of serotonin-increasing meds interact to make serotonin dangerously high
–Many antidepressants –Lithium –Parkinson’s meds –Demerol, some migraine meds, cold medicine –Amphetamines, cocaine, LSD, Ecstasy •Mortality: 11% |
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Serotonin Syndrome
Symptoms: |
–Agitation, confusion,
–Fever, diaphoresis, nausea, diarrhea –HR rapid, BP up & down –Loss of coordination, muscle rigidity, seizures |
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Serotonin Syndrome
Treatment: |
–Stop the med
–Supportive care of symptoms •Interventions as symptoms demand •May include ICU stay, intubation, neuromuscular paralysis to relax muscles and prevent further rhabdymyolysis •Cooling measures for hypothermia |
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ECT: Nursing Considerations
Before treatment begins |
Medical clearence, pre amesthia
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ECT: Nursing Considerations
during |
-moitor pts vs
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After treatment
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post anethsia, swallowing percautions
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Manic Episode: DSM IV
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At least 3 of the following must be present to a significant degree for at least 1 week.
•Grandiosity or inflated self esteem. •Decreased need for sleep. •Pressured speech •Flight of ideas or feeling of “thoughts racing”. •Distractibility. •Psychomotor agitation or MUCH goal-oriented activity •Excessive involvement in pleasurable activities with high potential for problems. |
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Hypomanic Episode
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•Meets most of the criteria for manic episode, but the episode is notsevere enough to:
–result in significant impairment, or to –require hospitalization |
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Bipolar I Disorder:
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–One or more manic or mixed episodes, usually with a major depressive episode.
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Bipolar II Disorder:
– |
Includes one or two major depressive episodes and at least one hypomanic episode
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Cyclothymic Disorder
. |
For at least 2 years:
•The patient has had numerous periods of hypomanic symptoms and numerous periods of depressed mood. •The patient has never experienced major depression |
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Etiology
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•Psychodynamic theories
–Family dynamics –Mania as defense against depression •Biological theory –Excessive levels or imbalance in neurotransmitters •Genetics Nursing Care -NPR: •Safety •Matter-of-fact approach •Clear, concise directions and comments •Interrupt if you need to -kindly. •Set limits calmly, but don’t set unimportant limits. •Keep assessing your countertransference! Don’t fall in. •Reinforce reality. |
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Nursing Care -NPR:
• |
Safety
•Matter-of-fact approach •Clear, concise directions and comments •Interrupt if you need to -kindly. •Set limits calmly, but don’t set unimportant limits. •Keep assessing your countertransference! Don’t fall in. •Reinforce reality. |
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Milieu Management
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Meet often with colleagues to defuse conflict and clarify communication.
•Consistency, consistency, consistency. •Decrease environmental stimuli. |
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Lithium
• |
A salt.
•Substitutes for sodium, changes neurons’ responses to neurotransmitters. •1 to 2 weeks for therapeutic response •Narrow “therapeutic window” - •maintenance blood levels 0.6 to 1.2. •blood levels over 1.5 toxic. •Fluid balance very important. |
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Lithium -Side Effects
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•ia and polydipsia
•Nausea •Dry mouth Polyur•Diarrhea •Thirst •Drowsiness •Mild hand tremor •Weight gain •Bloated feeling •Insomnia •Dizziness |
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Lithium -Adverse & Toxic Effects
• |
Diabetes insipidus
•Toxic effects depend on blood level: –Exacerbation of side effects, increasing to: –Extreme GI distress, –Muscular weakness –Ataxia –Multiple organ failure at high levels. •Note patient teaching needs |
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Diabetes insipidus
• |
Toxic effects depend on blood level:
–Exacerbation of side effects, increasing to: –Extreme GI distress, –Muscular weakness –Ataxia –Multiple organ failure at high levels. •Note patient teaching needs |