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33 Cards in this Set

  • Front
  • Back
learning
durable change in behavior or knowledge due to experience
memory
means by which past experience is drawn on to guide or direct behavior or thoughts in the present; conscious effort recall of things
Classical (Pavlonian) Conditioning (involuntary responses):
- who?
- describe this learning?
- Ivan Pavlov, Russian digestive physiologist
- organism learns a predicative relationship btwn 2 external stimuli; presentation of 1st specific stimulus predicts (almost guarantees) presentation of 2nd specific stimulus
acquisition
- define?
- part of what kind of learning?
- initial learning of predictive relationship btwn stimuli
- part of Pavlonian conditioning
unconditioned stimulus (UCS)
- define?
- Pavlov's example
- stimulus which already has meaning to an organism and generates a response on its own (UCR- unconditioned response)
- dog salivates (UCR) AFTER food is presented
conditioned stimulus (CS)
- define?
- Pavlov's example
- as organism acquires predictive relationship, CS will ellicit CR from organism in preparation of the UCS BEFORE the UCS is presented
- a bell (CS) rung before food arrived....bell's ringing reliably predicts food.....sound of bell cause dog to salivate (CR) BEFORE food available
extinction
- define
- Pavlov's example
- after acquisition, if CS is presented alone a lot without UCS following, the CR will eventually stop happening
-
spontaneous recovery
- describe
- Pavlov's example
- extinction is not erasure or forgetting
- bouts of CS w/o UCS => organism perform CR with less vigor/effort
- might need many times of CS-alone training before spontaneous recovery completely ceases (extinction>acquisition)
- after 1st day extinction training, each day when bell presented alone illicits small salivation til salivation stops
stimulus generalization
-defn
- Pavlov example
- stimuli w/ sensory qualities like CS elicits CR by mistake
- dog mistakes someone's keys jingling for the bell => salivation
stimulus discrimination
- person w/ keys walks by often => dog learns to salivate to bell and not keys
- becomes difficult when another second bell is introduced-- dog has difficulty learning the difference compared to keys but eventually generalization to the 2nd bell (evidenced by salivation to different bell) decreases and dog can discriminate between the 2 bell sounds
higher order conditioning
- describe
- Pavlov example
- series of CR to succession of stimuli can be chained together
- previously learned CS becomes so well trained that it becomes a new UCS to a new stimulus that predicts its occurance
- image of beach ball projected onto wall before bell is rung => image predicts bell which predicts food => bell becomes UCS for image which acts as new higher order
- image now generates salivation as a new higher order CR
Operant (Skinnerian) Conditioning (voluntary responses)
- consequences of a behavior come to guide and control occurance of that behavior
- organism "happens" to the world
reinforcement
- increases likelihood of a response
- use of terms positive reinforcement/negative reinforcement differ in nature of stimulus as reinforcer but both INCREASE occurance of behavior
ex) parent want child to clean room more so parent gives kid unexpected money when cleaning room => consequences are expected to INCREASE room-cleaning behavior
ex) parent spanks child, says "Gonna get another one if dont start cleaning room" (neg. reinf.) =.aversive stimulus applied then terminated when behavior INCREASES
punishment
- when stimulus applied to DECREASE occurence of behavior (parent threaten bad child)
- all forms of punishment do not involve applying aversive stimulus (ex. reward omission)
- goal: decrease occurrence of unwanted behavior
reward omission
- expected appetitive stimulus is removed/withheld
ex) parent take away cherished toy as consequence for child using swear words
- goal: decrease occurrence of unwanted behavior
neurotransmitter receptors
- ALL receptors have TWO separate binding sites for the transmitter (signal molecule)
- 2 molecules of the transmitter must attach to receptor binding sites SIMULTANEOUSLY to activate receptor
ligand-gated ion channels (ionotropic)
- distance relatives of voltage-dependent ion channels found on axon
- receptor binding sites act as mechanism for detecting presence of transmitter
- tubes that are closed until activated
- entrance of ions cause EPSPs and IPSPs
- caled ionotropic since allow ions to pass into the neurons
G-protein linked (metabotropic)
- metabotropic since do not directly cause electrical response, but cause biocmincal changes within neuron which may change neuron's metabolism
- DOES NOT have a pore as part of receptor
- when receptor activates,Gprotein becomes activated, travels membrane and changes activity of distant ion channels or membrane-bound enzymes => releases second messengers
second messengers
- can go from dendrite to as far as nucleus
- activate other enzymes or trigger manufacture of cellular proteins
ionotropic
- cause EPSPs or IPSPs, the electrical signals which directly determine if an action potential will occur
- like a telegraph key sending a message
metabotropic
- change neuron's metabolic state
- make cell more/less sensitive to EPSPs/IPSPs making it indirectly easier/harder to trigger action potential
- like volume controls, making the message louder or fainter
amino acids
- glutamate and GABA
along with serotin, are most widely used and important transmitters
glutamate (excitatory)
- most common nerotransmitter
- primary excitatory transmitter in brain
- from diet or synthesized as byproduct of Krebs
- sensory processing, learning, memory
GABA (inhibitory)
- gamma aminobutyric acid
- primary inhibitory neurotransmitter in brain
- sythesized from glutamate
- quiets nerve cells
- learning, memory, sensory processing, sleep/waking, relief from anxiety
peptides
- short proteins
- if outside brain, acts as hormones
- if within brain, acts as neurotransmitters
ex) cholcystokinin stimulates pancreas/liver in digestive system; but in brain has roles in pain, memory, anxiety, hunger
agonist
- a drug that INCREASES or facilitates activity or effect of the transmitter
- direct agonist impersonates transmitter and activates receptor
antagonist
- a drug that DECREASES, interferes, or blocks activity of transmitter
- direct antagonist can't impersonate receptor. It attaches itself to it but doesn't activate it
acetylcholine
(a neurotransmitter)
- only transmitter that needs enzymatic degradation to terminate signal
-sythesized from choline which is used as component of cell membrane and Acetyl-CoA
- broken down by AChase
comes from cholinergic basal forebrain (BF)
- learning, memory, sleeping/waking, sensory processing
basal forebrain's (BF) 2 most prominent structures
- septum
- nucleus basalis
monoamines
(neurotransmitter)
- share lone amino group
- classified into catecholamines and indolamines
- tyrosine-based
tyrosine-based monoamines
- basic building block for cateholamines
- compounds share catechol as part of structure (bensene ring with to hydroxide groups attached)
dopamine (DA)
(a monomine)
- sythesis- tyrosine converted to LDOPA by tyrosine hydroxylase. LDOPA is converted to dopamine by DOP Adecarboxylase
-2 sources: substantianigra (for voluntary movements), and ventral tegmental area (VTA) for brain systems
norepinephrine (NE)
(a monomine)
- produced by blue spot
cells first go through steps of manufacturing DA then dopamine-beta-hydroxylase converts dopamine to norepinephrine
- blue spot