Psych Substance/drugs - Ms3 - Part 2

Front 1

Chlorpromazine =

Back 1

alternate to Thioridazine - a typical antipsychotic

Front 2

myoclonic jerks ~~

Back 2

SER synd

Front 3

buspirone can *also* cause:

Back 3

SER synd

Front 4

remember that you have to wait _______________ after MAOI to start SSRI

Back 4

2 weeks

Front 5

Tx for Benzo *withdrawal* =

(2)

Back 5

benzo's (DCC vs. LOT)

CBZ/V

Front 6

LOT are not dependent on:

Back 6

liver for excretion

- best for elderly or liver dz

Front 7

***Tx of DTs = ***

Back 7

IV benzo's

(LOT)

Front 8

paranoia *is* a part of:

Back 8

psychosis

Front 9

you *MUST* treat psychosis with:

Back 9

antipsychotics, EVEN if it's secondary to depression

Front 10

mc complication of NMS =

Back 10

rhabdo

Front 11

most potent benzo =

Back 11

clonazepam

Front 12

CBC is _____________ for Li2+

Back 12

*optional*

Front 13

SSRI's during preg =>

Back 13

PHTN

Front 14

NSAIDs can cause inc in _____ lvls

Back 14

Li2+

- but aspirin does *not*

Front 15

Tx Tourette's =

Back 15

**atypicals, esp. Risperidone**

or

Clonidine / Guanfacine

- typicals for *severe* cases

Front 16

first step in treating depression refractory to SSRI =

Back 16

change to *another* SSRI

Front 17

only treatment for *possible* relief of Tardive Dyskinesia =

Back 17

*clozapine*

Front 18

Lamotrigine is cleared faster when given with:

Back 18

OCP's

Front 19

cyproheptadine =

Back 19

1st-gen antiHIST

Front 20

mc Li2+ EKG change =

Back 20

T-wave depression

Front 21

HCTZ => _____ Li2+ in blood due to _________________________________

Back 21

*increased* Li2+ in blood due to *decreased* renal clearance of Li2+

- same for metronidazole, tetracycline abx, and NSAIDs (sans aspirin)

Front 22

Tx for OCD =

(2)

Back 22

high-dose SSRI's (1st-line)

Clomipramine (2nd-line)

- *not* other TCA's

Front 23

for Tx-R OCD, combine SSRI with:

Back 23

**Risperidone**

Front 24

Tx for *refractory* psychosis =

Back 24

Clozapine

Front 25

main SE of TCA's =

Back 25

ortho hypo, via a1 blockage

- imipramine > nortriptyline

Front 26

Tx for delirium =

(2)

Back 26

1. low-stim environment

2. low-dose **ANTIPSYCHOTICS**

- avoid benzo's

Front 27

2 SE's of Mirtazapine =

Back 27

1. wt gain

2. sedation

(both opposite of methylphenidate)

Front 28

TCAs' cardiac effects =

Back 28

slowing of cardiac conduction

Front 29

SE's of Trazadone include:

Back 29

OH, like TCA's

Front 30

long QT seen in:

Back 30

ALL antipsychotics

Front 31

Haldol ~~ LESS ___________________

Back 31

antichol / ortho hypo

Front 32

naltrexone decreases ________________

Back 32

*craving* for alcohol

Front 33

wt gain is seen in *both*

Back 33

generations

- but more so in the atypicals

Front 34

prazosin is nly for:

Back 34

HTN, BPH

Front 35

Risperidone =>

Back 35

metabolic syndrome, but *also* OH via a1

Front 36

big fear with quetiapine =

Back 36

sudden death in elderly

Front 37

*3 biggest causes of severe AMS:*

Back 37

1. hypoglycemia

2. alc intoxication

3. opioid OD

Front 38

best med for opioid detox =

Back 38

buprenorphine

- except methadone in preg

Front 39

**duloxetine ALSO treats:**

Back 39

neuropathic pain

Front 40

Tx for bulimia and binge-eating disorder =

(2)

Back 40

1. SSRI's (esp. fluoxetine)

2. Topiramate

Front 41

_____________ is contraindicated in EoD due to _______________________________

Back 41

buproprion contraindicated in EoD due to lower sez thresholds

Front 42

TCA's no good in CV conditions b/c they:

Back 42

inc. HR, dec. BP ==> inc mortality

Front 43

Tx akathisia =

(2)

Back 43

B-blocker (1st)

2nd-line = benzo

Front 44

most dangerous class to abruptly withdraw from =

Back 44

sedatives/anxiolytics

Front 45

glucose before thiamine ==>

Back 45

Wernicke (CAN)

Front 46

Tx DTs =

Back 46

LOT

- *not* diazepam

Front 47

pimozide =

Back 47

1st-gen antipsychotic

~~ lots of interactions with other meds, => inc. QTc

Front 48

worst offender for metabolic syndrome =

Back 48

Clozapine

- also most effective

Front 49

SSRI's can induce _________ in ______

Back 49

SSRI's can induce SI in kids/young adults

Front 50

**bupropion ~~

(2)

Back 50

1. *no* sexual SE's

2. often *combined* with SSRI's to dec. their sexual symps

Front 51

ALL antidepressants except for (2) cause sexual dysfunction

Back 51

1. bupropion

2. mirtazapine

Front 52

2 antipsychotics available IM:

Back 52

1. risperidone

2. haldol

Front 53

trazadone is NOT _______-__________; safe in _______

Back 53

trazadone is NOT habit-forming; safe in PTSD insomnia

Front 54

take SSRI for 6-12 mths, depending on:

Back 54

severity and rf's

Front 55

Clozapine can cause (CV issue):

Back 55

persistent sinus tachy;

=> add propranolol

Front 56

which depression symptom takes the longest to go away with tx?

Back 56

SI

Front 57

ALL 2nd-gen antipsy have less:

Back 57

TD than 1st-gen

Front 58

lowest rates of metabolic syndrome in atypicals =

Back 58

aripiprazole and ziprasidone

- oxazapine and clozapine = highest

Front 59

zaleplon is best for:

Back 59

*middle* insomnia

(falling asleep but waking up frequently)

(vs. initial insomnia)

Front 60

clonazepam does NOT interact with:

Back 60

warfarin

Front 61

SE's of topiramate:

(3)

Back 61

1. kidney stones

2. cognitive impairment

3. wt loss

Front 62

in ethylene glycol poisoning, you will see:

Back 62

calcium oxalate stones

Front 63

blepharospasm = spasm of:

Back 63

eyelids

Front 64

opisthotonos =

Back 64

arching of neck and back

Front 65

Tx for postpartum depression with psychotic features =

Back 65

SSRI *and* antipsy

Front 66

bilateral abducens nerve palsy ~~

Back 66

Wernicke

=> IV thiamine + CT

Front 67

Tx Delusional Disorder =

Back 67

**antipsyhcotic**

- not SSRI

Front 68

command auditory hallucinations =

Back 68

EMERGENCY

Tx = **restart neuroleptic**

Front 69

Temp >102 =

Back 69

emergency - get cooling blanket

Front 70

atropine =

Back 70

antimuscarinic

- *blocks* ACH

=> anticholinergic effects