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37 Cards in this Set
- Front
- Back
Name the 4 Monoamines neurotransmitters.
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1. Dopamine (DA)
2. Norepinephrine (NE) (noradrenaline) 3. Serotonin (5-HT) 4. Histamine |
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What are the 5 receptors of the Dopamine (DA) transmitter?
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D1, D2, D3, D4, D5
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What are the effects/functions of Dopamine (DA)?
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1. Involved in fine muscle movement.
2. Involved in integrating of emotions and thoughts. 3. Involved in decision making. 4. Stimulates hypothalamus to release hormones (sex, thyroid, adrenal) |
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What mental illnesses are associated with decreased level of dopamines (DA)? (2)
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1. Parkinson's disease
2. Depression |
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What mental illnesses are associated with increased level of dopamines (DA)? (2)
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1. Schizophrenia
2. Mania |
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What are the 4 receptors of Norepinephrine (NE) (noradrenaline)?
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1. alpha 1
2. alpha 2 3. beta 1 4. beta 2 |
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What are the effects/functions of Norepinephrine (NE) (noradrenaline)? (2)
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1. Level in brain affects mood.
2. Stimulates sympathetic branch of autonomic nervous system for "fight or flight" in response to stress. |
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What mental illness is associated with decreased level of Norepinephrine (NE) (noradrenaline)?
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Depression
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What mental illnesses are associated with a increase level of Norepinephrine (NE) (noradrenaline)? (3)
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1. Mania
2. Anxiety states 3. Schizophrenia |
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What are the 4 receptors of Serotonin (5-HT)?
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5-HT, 5-HT2, 5-HT3, 5-HT4
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What are the effects/functions of Serotonin (5-HT)? (2)
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1. Plays a role in sleep regulation, hunger, mood states, and pain perception.
2. Plays role in aggression and sexual behavior. |
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What mental illness is associated with a decrease level of Serotonin (5-HT)?
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Depression
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What mental illness is associated with a increase level of Serotonin (5-HT)?
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Anxiety
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What are the 2 receptors of Histamine?
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H1, H2
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What are the effects/functions of Histamine?
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1. Involved in alertness
2. Involved in inflammatory response 3. Stimulates gastric secretion |
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What mental illness are associated with a decrease level of Histamine?
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1. Depression
2. Sedation 3. Weight gain |
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What are the two amino acids transmitters?
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1. Gama-aminobutyric acid (GABA)
2. Glutamate |
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What are the 2 receptors of Gama-aminobutyric acid (GABA)?
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GABAa, GABAb
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What are the effects/functions of Gama-aminobutyric acid (GABA)? (3)
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1. Plays a role in inhibition; reduces agression, excitation, and anxiety.
2. May play a role in pain perception. 3. Has anticonvulsant and muscle-relaxing properties. |
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What mental illnesses are associated with a decrease level of Gama-aminobutyric acid (GABA)? (3)
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1. Anxiety disorders
2. Schizophrenia 3. Huntington's disease |
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What are the 2 receptors of Glutamate?
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1. NMDA
2. AMPA |
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What are the effects/functions of Glutamate?
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1. Is excitatory
2. Plays role in learning and memory. |
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What mental illness is associated with a decrease level of (NMDA) Glutamate?
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Psychomimetic state that resembles schizophrenia.
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How is increased level of (AMPA) Glutamate associated with mental health?
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Improvement of cognitive performance on behavior tasks.
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What transmitter is classified as Cholinergic?
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Acetylcholine (ACh)
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What are the 2 receptors of Acetylcholine (ACh)
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Nicotinic
Muscarinic (M1, M2, M3) |
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What are the effects/functions of Acetylcholine (ACh)? (4)
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1. Plays a role in learning, memory.
2. Regulates mood: mania, sexual aggression 3. Affects sexual and aggressive behaviors 4. Stimulates parasympathetic nervous system. |
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What mental illnesses are associated with a decrease level of Acetylcholine (ACh)?
(3) |
1. Alzheimer's disease
2. Huntington's Chorea 3. Parkingson's Disease |
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What mental illness is associated with a increase level of Acetylcholine (ACh)?
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Depression
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What are the 3 neuro peptides (Neuromodulators) transmitters?
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1. Substance P (SP)
2. Somatostatin (SRIF) 3. Neurotensin (NT) |
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What are the effects/functions of Substance P (SP)? (3)
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1. Centrally active SP antagonist has antidepressant and antianxiety effects in depression.
2. Promotes and reinforces memory. 3. Enhances sensitivity to pain receptors to activate |
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How is Substance P (SP) associated with mental health?
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1. Involved in regualtion of mood and anxiety.
2. Role in pain management |
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What is the effect/function of Somatostatin (SRIF)?
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Altered levels associated with cognitive disease.
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What mental illnesses are associated with a decrease level of Somatostatin (SRIF)? (2)
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1. Alzheimer's disease
2. Depression: Decrease levels of SRIF found in spinal fluid of some depressed clients. |
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What mental illness is associated with a increase level of Somatostatin (SRIF)?
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Huntington's chorea
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What is the effect/function of Neurotensin (NT)?
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Endogenous antipsychotic-like properties.
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What mental illness is associated with decrease Neurotensin (NT)?
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Schizophrenic: decrease levels found in spinal fluid of schizophrenic clients.
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