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14 Cards in this Set

  • Front
  • Back
Selective Serotonin Reuptake Inhibitors (SSRI’s)-Adverse Reactions
Initial nausea, loose bowel movements
insomnia
° Toxic effects (rare): serotonin syndrome
° Concern regarding increased suicidal
potential as yet unproven through longterm
studies
sexual dysfunction
SSRI-meds
Celexa, Prozac, Luvox, Paxil, Zoloft, Lexapro
Atypical Antidepressants
Wellbutrin, Zyban, Desyrel
Wellbutrin-SE
induced seizure if more than 300mg. Some nausea.

NO-weight gains, sexual dysfunctions.
Dual-Action Reuptake Inhibitors – SNRIs (Serotonin and Norepinephrine)- meds
Effexor, Remeron, Duloxetine
AntiConvultsant
Antiepileptic Drugs (AEDs)-Bipolar meds
Tegretol, Depakene, Lamictal, Neurontin, Topamax

PRN MAY BE USED IN 10-14 DAYS: BENZODIAZEPINES& ANTIPSYCHOTICS
Tegretol -SE
°Agranulocytosis and aplastic anemia are most serious side
effects.
°Blood levels should be monitored throughout first 8 weeks
because drug induces liver enzymes that speed its own
metabolism. Dosage may need to be adjusted to maintain serum
level of 6-8mg/L.
°Sedation is most common problem; tolerance usually develops.
°Diplopia, incooridination, and sedation can signal excessive
levels.
Depakene- SE
°Baseline live function test should be performed and results
monitored at regular intervals. Hepatitis, although rare, has
been reported, with fatalities in children.
°Signs and symptoms to watch for include fever, chills, right
upper quadrant pain, dark urine, malaise, and jaundice.
°Common side effects include tremors, gastrointestinal upset,
weight gain, and rarely, alopecia.
Lamictal SE
°Life-threatening rash reported in 3 out of every 1000 individuals
(Steven-Johnson syndrome).
°Use caution when renal, hepatic, or cardiac function is impaired.
°Dizziness, diplopia, headaches, ataxia, and somnolence are
amoung frequent side effects.
Neurontin SE
°Most serious adverse effects are difficulty in breathing, swelling
of the lips, rash, slurred speech, drowsiness, and diarrhea.
°Fatigue, somnolence, dizziness, ataxia, diplopia, hypertension
are the more frequent side effects.
°Used off label; not presently FDA approved for bipolar disorder.
Topamax SE
°Used in acute mania or in combination with other drugs.
°Adverse effects include weight loss, congnitive side effects,
fatigue, dizziness, and paresthesia.
°Used off label; not presently FDA approved for bipolar disorder.
Atypical 2nd generation Antipsychotic Agents Meds
Clozaril, Risperdal, Zyprexa, Seroquel, Geodon, Abilify
MAOI adverse reactions
insomnia, orthostatic hypotension, peripheral edema, sedation, weight gain, sexual dysfunction, no tyramine foods (smoke, preserved, baked)
Tricyclic antidepressants (TCA) SE
orthostasis, lethal in overdose, CHF effects(tachycardia, dysruthmias, ECG changes, heart failure)
Anticolinergic SE- dry mouth, blurred vision, constipation, urinary retention, tachycardia, possible confusion.