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14 Cards in this Set
- Front
- Back
Selective Serotonin Reuptake Inhibitors (SSRI’s)-Adverse Reactions
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Initial nausea, loose bowel movements
insomnia ° Toxic effects (rare): serotonin syndrome ° Concern regarding increased suicidal potential as yet unproven through longterm studies sexual dysfunction |
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SSRI-meds
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Celexa, Prozac, Luvox, Paxil, Zoloft, Lexapro
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Atypical Antidepressants
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Wellbutrin, Zyban, Desyrel
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Wellbutrin-SE
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induced seizure if more than 300mg. Some nausea.
NO-weight gains, sexual dysfunctions. |
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Dual-Action Reuptake Inhibitors – SNRIs (Serotonin and Norepinephrine)- meds
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Effexor, Remeron, Duloxetine
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AntiConvultsant
Antiepileptic Drugs (AEDs)-Bipolar meds |
Tegretol, Depakene, Lamictal, Neurontin, Topamax
PRN MAY BE USED IN 10-14 DAYS: BENZODIAZEPINES& ANTIPSYCHOTICS |
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Tegretol -SE
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°Agranulocytosis and aplastic anemia are most serious side
effects. °Blood levels should be monitored throughout first 8 weeks because drug induces liver enzymes that speed its own metabolism. Dosage may need to be adjusted to maintain serum level of 6-8mg/L. °Sedation is most common problem; tolerance usually develops. °Diplopia, incooridination, and sedation can signal excessive levels. |
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Depakene- SE
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°Baseline live function test should be performed and results
monitored at regular intervals. Hepatitis, although rare, has been reported, with fatalities in children. °Signs and symptoms to watch for include fever, chills, right upper quadrant pain, dark urine, malaise, and jaundice. °Common side effects include tremors, gastrointestinal upset, weight gain, and rarely, alopecia. |
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Lamictal SE
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°Life-threatening rash reported in 3 out of every 1000 individuals
(Steven-Johnson syndrome). °Use caution when renal, hepatic, or cardiac function is impaired. °Dizziness, diplopia, headaches, ataxia, and somnolence are amoung frequent side effects. |
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Neurontin SE
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°Most serious adverse effects are difficulty in breathing, swelling
of the lips, rash, slurred speech, drowsiness, and diarrhea. °Fatigue, somnolence, dizziness, ataxia, diplopia, hypertension are the more frequent side effects. °Used off label; not presently FDA approved for bipolar disorder. |
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Topamax SE
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°Used in acute mania or in combination with other drugs.
°Adverse effects include weight loss, congnitive side effects, fatigue, dizziness, and paresthesia. °Used off label; not presently FDA approved for bipolar disorder. |
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Atypical 2nd generation Antipsychotic Agents Meds
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Clozaril, Risperdal, Zyprexa, Seroquel, Geodon, Abilify
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MAOI adverse reactions
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insomnia, orthostatic hypotension, peripheral edema, sedation, weight gain, sexual dysfunction, no tyramine foods (smoke, preserved, baked)
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Tricyclic antidepressants (TCA) SE
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orthostasis, lethal in overdose, CHF effects(tachycardia, dysruthmias, ECG changes, heart failure)
Anticolinergic SE- dry mouth, blurred vision, constipation, urinary retention, tachycardia, possible confusion. |