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73 Cards in this Set
- Front
- Back
what class of drug is buprioprion?
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atypical antidepressant
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what is buproprion used for?
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depression, smoking cessation
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MOA of buprioprion?
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increase NE, Dopamine
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SE of buproprion?
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stimulant effect, headache, seizures in bulimics
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class of Mirtazapine?
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atypical antidepressant
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MOA of Mirtazapine?
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α2 antagonist --> ↑ NE, serotonin release; 5-HT2+3 receptor antagonist
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SE of Mirtazapine?
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sedation, weight gain, dry mouth
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class of Maprotiline?
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atypical antidepressant
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MOA Maprotiline?
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block NE reuptake
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SE of Maprotiline?
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sedation, orthostatic hypotension
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class of Trazodone?
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atypical antidepressant
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MOA of Trazodone?
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block serotonin reuptake
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use of Trazodone?
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depression, insomnia
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SE of Trazodone?
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priapism, sedation, nausea, postural hypoTN
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use of MAOIs?
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atypical depression, anxiety, hypochondriasis
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SE of MAOIs?
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HTN crisis
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CI of MAOIs?
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SSRIs, meperidine
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class of Phenelzine?
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MAOI
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class of Tranylcypromine
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MAOI
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class of Isocarboxazid?
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MAOI
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class of Selegiline?
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MAO-B inhibitor
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SE of SNRIs?
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↑ BP, stimulant
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class of Venlafaxine?
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SRNI
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use of Venlafaxine?
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depression, generalized anexity disorder
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class of Duloxetine?
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SNRI
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use of Duloxetine?
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depression, diabetic peripheral neuropathy
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use of SSRIs?
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depression, OCD, bulemia, social phobia
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SE of SSRIS?
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serotonin syndrome, sexual dysfunction, GI
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what is serotonin syndrome?
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hyperthermia, muscle rigidity, CV collapse, flushing, diarrhea, seizures
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how to treat serotonin syndrome?
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Cyproheptadine
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class of paroxetine?
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SSRI
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class of Sertraline?
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SSRI
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class of Citalopram?
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SSRI
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MAO TCAs?
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block NE, serotonin reuptake
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SE of TCAs?
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α blocking, anticholinergic, cardiotox, coma, convulsions, sedation
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class of Imipramine?
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TCA
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use of Imipramine?
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depression, bed wetting
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class of Amitriptyline?
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TCA, 3rd generation
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class of Despiramine?
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TCA (least sedating, lowest seizure threshold)
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class of Nortriptyline?
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TCA
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class of Clomipramine?
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TCA
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use of Clomipramine?
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depression, OCD
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class of Doxepin?
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TCA
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MAO Buspirone?
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stimulate 5-HT1a receptors
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use of Buspirone?
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generalized anxiety disorder
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SE of Lithium?
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LMNOP: mvt (tremor), nephrogenic DI, hypotyroid, pregnancy problems (Ebstein)
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Ebstein anomaly
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apical displacement of TC valve leaflets, ↓ RV volume, atrialization of RV
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MAO atypical antipsychotics
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block 5-HT2, Dopamine, α1, H1 receptors
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use of atypical antipsychotics?
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schizophrenia
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class of Olanzapine?
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atypical antipsychotic
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use of Olanzapine?
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schizophrenia, OCD, anxiety, depression, mania, Tourette's
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SE of Olanzapine?
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weight gain
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class of Clozapine?
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atypical antipsychotic
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SE of Clozapine?
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agranulocytosis
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class of Quetiapine?
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atypical antipsychotic
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class of Risperidone?
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atypical antipsychotic
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class of Aripiprazole?
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atypical antipsychotic
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class of Ziprasidone?
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atypical antipsychotic
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MAO of antipsychotics (neuroleptics)?
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block D2 receptors --> ↑ cAMP
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drugs belonging to antipsychotics?
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haloperidol + "azines"
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use of antipsychotics?
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schizophrenia (+ symptoms), psychosis, acute mania, Tourette's
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SE of antipsychotics?
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lipid soluble, extrapyramidal, hyperprolactin, anti muscarinie, anti α1, anti H1, NMS, tardive dyskinesia
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Neuroleptic malignant syndrome
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"fever" - fever, encephalopathy, vitals unstable, ↑ enzyme activity, rigidity
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treatment of NMS?
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dantrolene
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class of haloperidol?
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antipsychotic, high potency
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class of trifluoperazine?
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antipsychotic, high potency
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class of Fluphenazine?
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antipsychotic, high potency
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class of Thioridazine?
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antipsychotic, low potency
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which antipsychotic SE = retinal deposits?
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Thioriadazine
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class of Chlorpromazine?
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antipsychotic, low potency
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which antipsychotic SE = corneal deposits?
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Chlorpromazine
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MOA CNS stimulants?
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↑ catecholamines @ synaptic cleft, esp NE, Dopamine
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SE of CNS stimulants?
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nervousness, insomnia
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