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73 Cards in this Set

  • Front
  • Back
what class of drug is buprioprion?
atypical antidepressant
what is buproprion used for?
depression, smoking cessation
MOA of buprioprion?
increase NE, Dopamine
SE of buproprion?
stimulant effect, headache, seizures in bulimics
class of Mirtazapine?
atypical antidepressant
MOA of Mirtazapine?
α2 antagonist --> ↑ NE, serotonin release; 5-HT2+3 receptor antagonist
SE of Mirtazapine?
sedation, weight gain, dry mouth
class of Maprotiline?
atypical antidepressant
MOA Maprotiline?
block NE reuptake
SE of Maprotiline?
sedation, orthostatic hypotension
class of Trazodone?
atypical antidepressant
MOA of Trazodone?
block serotonin reuptake
use of Trazodone?
depression, insomnia
SE of Trazodone?
priapism, sedation, nausea, postural hypoTN
use of MAOIs?
atypical depression, anxiety, hypochondriasis
SE of MAOIs?
HTN crisis
CI of MAOIs?
SSRIs, meperidine
class of Phenelzine?
MAOI
class of Tranylcypromine
MAOI
class of Isocarboxazid?
MAOI
class of Selegiline?
MAO-B inhibitor
SE of SNRIs?
↑ BP, stimulant
class of Venlafaxine?
SRNI
use of Venlafaxine?
depression, generalized anexity disorder
class of Duloxetine?
SNRI
use of Duloxetine?
depression, diabetic peripheral neuropathy
use of SSRIs?
depression, OCD, bulemia, social phobia
SE of SSRIS?
serotonin syndrome, sexual dysfunction, GI
what is serotonin syndrome?
hyperthermia, muscle rigidity, CV collapse, flushing, diarrhea, seizures
how to treat serotonin syndrome?
Cyproheptadine
class of paroxetine?
SSRI
class of Sertraline?
SSRI
class of Citalopram?
SSRI
MAO TCAs?
block NE, serotonin reuptake
SE of TCAs?
α blocking, anticholinergic, cardiotox, coma, convulsions, sedation
class of Imipramine?
TCA
use of Imipramine?
depression, bed wetting
class of Amitriptyline?
TCA, 3rd generation
class of Despiramine?
TCA (least sedating, lowest seizure threshold)
class of Nortriptyline?
TCA
class of Clomipramine?
TCA
use of Clomipramine?
depression, OCD
class of Doxepin?
TCA
MAO Buspirone?
stimulate 5-HT1a receptors
use of Buspirone?
generalized anxiety disorder
SE of Lithium?
LMNOP: mvt (tremor), nephrogenic DI, hypotyroid, pregnancy problems (Ebstein)
Ebstein anomaly
apical displacement of TC valve leaflets, ↓ RV volume, atrialization of RV
MAO atypical antipsychotics
block 5-HT2, Dopamine, α1, H1 receptors
use of atypical antipsychotics?
schizophrenia
class of Olanzapine?
atypical antipsychotic
use of Olanzapine?
schizophrenia, OCD, anxiety, depression, mania, Tourette's
SE of Olanzapine?
weight gain
class of Clozapine?
atypical antipsychotic
SE of Clozapine?
agranulocytosis
class of Quetiapine?
atypical antipsychotic
class of Risperidone?
atypical antipsychotic
class of Aripiprazole?
atypical antipsychotic
class of Ziprasidone?
atypical antipsychotic
MAO of antipsychotics (neuroleptics)?
block D2 receptors --> ↑ cAMP
drugs belonging to antipsychotics?
haloperidol + "azines"
use of antipsychotics?
schizophrenia (+ symptoms), psychosis, acute mania, Tourette's
SE of antipsychotics?
lipid soluble, extrapyramidal, hyperprolactin, anti muscarinie, anti α1, anti H1, NMS, tardive dyskinesia
Neuroleptic malignant syndrome
"fever" - fever, encephalopathy, vitals unstable, ↑ enzyme activity, rigidity
treatment of NMS?
dantrolene
class of haloperidol?
antipsychotic, high potency
class of trifluoperazine?
antipsychotic, high potency
class of Fluphenazine?
antipsychotic, high potency
class of Thioridazine?
antipsychotic, low potency
which antipsychotic SE = retinal deposits?
Thioriadazine
class of Chlorpromazine?
antipsychotic, low potency
which antipsychotic SE = corneal deposits?
Chlorpromazine
MOA CNS stimulants?
↑ catecholamines @ synaptic cleft, esp NE, Dopamine
SE of CNS stimulants?
nervousness, insomnia