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44 Cards in this Set
- Front
- Back
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Which SSRI can cause constipation and has anti-cholinergic effects?
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Paroxetine (Paxil)
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Which SSRI can cause diarrhea when beginning treatment?
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Sertraline (Zoloft)
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Which SSRI is approved only for OCD?
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Fluvoxamine (Luvox)
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Which SSRI has a lot of drug interactions per lecture?
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Fluvoxamine (Luvox)
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Which SSRI can give you vivid dreams?
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Escitalopram (Lexapro)
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Which SSRI has a 1-4 day 1/2 life?
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Fluoxeine (Prozac)
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Which drug class selectively inhibits the reptake of 5-HT into the presynaptic neuron?
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SSRI's
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What are the symptoms of serotonin syndrome?
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AMS, hyper-reflexia, excessive sweating, tremor, fever
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Which drug is contraindicated with SSRI's?
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MAOI's
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How do the TCA's work?
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- Reduce the reuptake of NE and 5-HT
- Prolongs the synaptic availability of the biogenic amines and hence their action at receptors |
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Which anti-depressant agent binds to alpha adrenergic, histaminergic, and cholinergic receptors (creates side effects)?
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TCA's
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Which anti-depressant should be avoided when your patient has glaucoma, thyroid disease, seizures, CV disease, elderly, etc?
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TCA's
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What are the 2 approved indications for Buproion (Wellbutrin, Zyban)?
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MDD
smoking cessation |
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Which one thing should you remember about Nefazodone (Serzone) per lecture?
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don't use in hepatic failure
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Weight gain Weight gain Weight gain....
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Mirtazapine (Remeron)
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MOA of MAOI's?
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Block the enzyme (monoamine oxidase) responsible for the breakdown of NE, 5-HT, DA within the nuronal synapse
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Which antidepressant can cause hypertensive crisis?
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MAOI's
shouldn't be on any other drugs that increase B/P |
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Which antidepressant requires a "wash out" period?
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MAOI's
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MOA of first generation anti-psychotics
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Primarily Dopamine blockade
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MOA of 2nd generation anti-psychotics
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Seratonin blockade
alpha-1 blockade much less dopamine blockade than in 1st generation |
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Which patients are good candidates for lithium therapy?
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bipolar disorder
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What effect may lithium have on thryoid levels?
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hypothyroid
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Which SSRI is used for bulemia?
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Fluoxetine (prozac)
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Which atypical antidepressant is approved for tx of diabetic neuropathy?
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Duloxetine (cymbalta)
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Which Atypical antidepressant causes weight gain and sedation (but the higher the dose the less sedation)?
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Mirtazapine (Remeron)
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Which Atypical antidepressant can cause priapism?
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Trazodone (Desyrel)
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If you have a suicidal pt that you are prescribing TCS's to - what is the limit of drug you would write per script?
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2 grams.
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Which anticonvulsant medication can auto-induce its own metabolism?
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Carbamazepine (tegretol)
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Which anticonvulsant med can cause rash (SJS)
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Lamotrigine (lamictal)
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Which anticonvulsant med can cause weight loss and nephrolithiasis?
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Topiramate (Topamax)
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Which anticonvulsant med can cause hyponatremia?
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Oxycarbazepine (trileptal)
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Which are the front line drugs for generalized absence seizures?
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Ethosuximide
Valproic Acid Lamotrigine |
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Which are the front line meds for generalized myoclonic seizures?
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Valproic acid
Clonazepam |
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Which are front line meds for partial seizures?
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Valproic acid
Carbamazepine Phenytoin Lamotrigine Oxcarbazepine Phenobarbitol Topiramate |
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Which are the front line meds for generalized tonic-clonic seizures?
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Phenytoin
Carbamazepine Valproic Acid Phenobarbitol |
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Which seizure med can cause nystagmus, ataxia, drowsiness, gingival hyperplasia, hirsutism, acne, rash, hepatotoxicity?
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Phenytoin
(Dilantin) |
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Which seizure med is a sulfa derivative?
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Zonisamide (Zonegran)
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Which seizure med can cause hepatotoxicity, N/V, weight gain, thrombocytopenia, pancreatitis, and alopecia?
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Valproic acid (depakote)
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Which antiseizure med can cause paresthesias, weight loss, renal stones?
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Topiramate (Topamax)
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What are the short term SE of Levodopa/Carbidopa?
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N/V, orthostatic hypotension, arrythmias, confusion, hallucinations, agitation
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What are the long term SE of Levodopa/Carbidopa?
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wearing off syndrome, dyskinesias
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What are 2 MAOBI's that are used for "wearing off" of Levodopa/Carbidopa?
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Selegiline
Rasagiline |
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What are 2 (COMT inhibitors) used for "wearing off" of Levodopa/Carbidopa?
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Tolcapone
Entacopone |
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Which COMT inhibitor is severly restricted due to hepatoxiticty --- you need to sign consent to take?
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Tolcapone
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