Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
95 Cards in this Set
- Front
- Back
alcohol withdrawal
|
benzodiazipines
|
|
bulimia
|
SSRIs
|
|
anxiety
|
benzodiazepines
buspirone SSRIs |
|
ADHD
|
methyphenidate
amphetimines |
|
atypical depression
|
MAO inhibitors
SSRIs |
|
Bipolar disorder
|
lithium
valproic acid carbamazepine |
|
depression
|
SSRIs and SNRIs
clomipramine |
|
panic disorder
|
SSRIs
TCAs benzodiazepines |
|
PTSD
|
SSRIs
|
|
schizophrenia
|
antipsychotics
|
|
tourette's syndrome
|
antipsychotics
(haloperidol and resperidone) |
|
social phobias
|
SSRIs
|
|
trigeminal neuralgia
|
carbamazepine
|
|
these drugs increase the catecholamines at the synaptic cleft, especially NE and Dopamine
|
CNS stimulants
methylpenidate dextroamphetimin |
|
narcolepsy (to stay awake during the day)
|
CNS stimulants
methylpenidate dextroamphetimin |
|
olanzapine
|
atypical antipsychotic
|
|
clozapine
|
atypical antipsychotic
|
|
quetiapine
|
atypical antipsychotic
|
|
risperidone
|
atypical antipsychotic
|
|
aripiprazole
|
atypical antipsychotic
|
|
ziprasidone
|
atypical antipsychotic
|
|
haloperidol
|
antipsychotic (neuroleptics)
|
|
trifluoperazine
|
antipsychotic (neuroleptics)
|
|
fluphenazine
|
antipsychotic (neuroleptics)
|
|
thioridazine
|
antipsychotic (neuroleptics)
|
|
chlorpromazine
|
antipsychotic (neuroleptics)
|
|
memory tool for the antipsychotics (neuroleptics)
|
Haloperidol + "azines''
|
|
amitriptyline
|
TCA
|
|
nortiptyline
|
TCA
|
|
imipramine
|
TCA
|
|
desipramine
|
TCA
|
|
clomipramine
|
TCA
|
|
doxepin
|
TCA
|
|
amoxapine
|
TCA
|
|
memory tool for TCAs
|
"iptyline" or "iprimine"
|
|
fluoxetine
|
SSRIs
|
|
paroxetine
|
SSRIs
|
|
sertraline
|
SSRIs
|
|
citalipram
|
SSRIs
|
|
venlafaxine
|
SNRIs
|
|
duloxetine
|
SNRIs
|
|
nefazodone
|
SNRIs
|
|
milnacipran
|
SNRIs
|
|
tranylcypromine
|
MAOIs
|
|
phenelzine
|
MAOIs
|
|
isocarboxazid
|
MAOIs
|
|
selegiline
|
MAOIs
|
|
these drugs block dopamine D2 receptors (and increase cAMP)
|
antipsychotics (neuroleptics)
haloperidole + 'azines' |
|
highly lipid soluble and stored in body fat and therefore very slow to be removed from body
|
antipsychotics (neuroleptics)
haloperidole + 'azines' |
|
cause extramyramidal AEs
|
antipsychotics (neuroleptics)
haloperidole + 'azines' |
|
may lead to hyperprolactinemia and galactorrhea
|
antipsychotics (neuroleptics)
haloperidole + 'azines' results from dopamine receptor antagonism |
|
antimuscarinic AEs such as dry mouth and constipation, atihistamine effects (sedation) as well as alpha blockade (leading to hypotension)
|
antipsychotics (neuroleptics)
Low potency: chlorpromazine and thioridazine |
|
these drugs have "varied effects on 5HT2, dopamine, alpha receptors and H1 receptors
|
atypical antipsychotics
olonzapine, clozapine, quetapine, risperidone, aripiprazole, ziprasidone |
|
may lead to tardive dyskinesia
|
antipsychotics (neuroleptics)
high potency: haliperidol, fluphenazine, trifluoperazine |
|
acute mania
|
antipsychotics
(haloperidol and 'azines') |
|
OCD
|
olanzapine
(atypical antipsychotic) |
|
significant weight gain
|
olanzapine and clozapine
(atypical antipsychotic) |
|
aganulocytosis
|
clozapine
(atypical antipsychotic) |
|
prolongs QT interval
|
ziprasidone
|
|
SIADH
|
lithium
|
|
LMNOPs of lithiums AEs
|
lithium:
movement (tremor) Neprhogenic DI (ADH antagonist) hypOthyroidism pregnancy problems |
|
can you give lithim during pregnancy
|
nope
teratogenic |
|
stimulates 5HT1a receptors
|
buspirone
used for GAD |
|
GAD
|
buspirone
|
|
describe the evolution of extrapyramidal side effects and the causitve drugs
|
antipsychotics (haloperidol and AZINES)
4 hours- acute dystonia (muscle spasm, stiffness) 4 days- akinesia (parkinsonism) 4 weeks- akathisia (restlessness) 4 months- tardive diskinesia (lips smacking) |
|
describe neuroleptic malignant syndrome
|
fever
encephalopathy vitals unstable elevated enzymes rigidity of muscles |
|
patient comes in with fever, unstable vitals, elevated enzymes (myoglobinuria), and rigid muscles... most likely Dx? Tx?
|
Neuroleptic malignant syndrome (NMS)
treat with dantroline |
|
these drugs block the reuptake of NE and serotonin
|
TCAs
|
|
bedwetting
|
imipramine (TCA)
|
|
fibromyalgia
|
TCAs
|
|
only two TCAs that dont end in "iptyline" or "ipramine"
|
doxepin and amoxapine
|
|
causes anticholinergic effects like urinary retention and tachycardia
|
TCAs
|
|
sedation, alpha blocking effects, atropine-like effects,
|
TCAs
|
|
which TCA is the elast sedating and has the lowest seizure threshold
|
despiramine
|
|
convulsions, coma, cardiotoxicity (arrythmias)
|
TCAs
|
|
convulsions, coma and cardiotoxicity (arrhythmias)
|
TCAs
|
|
how do you treat the cardiotoxicity (arrythmias) caused by TCAs
|
NaHCO3
|
|
sexual dysfunction and GI distress
|
SSRIs
|
|
serotonin syndrome
|
SSRIs + MAOIs
|
|
hyperthermia, myoclonus, cardiovascular colapse, flushing, diarrhea, seizures
|
serotonin syndrome
|
|
how do you treat serotonin syndrome
|
cyproheptadine (5HT2 receptor antagonist)
along with cooling and benzos |
|
inhibits ONLY the reuptake of serotonin
|
SSRIs
|
|
inhibits to reuptake of serotonin and NE
|
SNRIs
|
|
diabetic peripheral neuropathy
|
duloxetine (SNRIs)
|
|
increase in BP, sedation and nausea
|
SNRIs
|
|
depression refractory to most all other treatment
|
MAOIs
|
|
hypertensive crisis with tyamine ingestion (wine and cheese...and anything aged really)
|
MAOIs
|
|
smoking cessation
|
buproprion
|
|
causes seizures in bulimic patients
|
buproprion
|
|
has no sexual side effects
|
buproprion
|
|
alpha-2 antagonist (increases the release of NE and serotonin) as well as being a potent 5HT2 and 5HT3 receptor antagonist)
|
mirtazapine
|
|
perfect antidepressant for an old lady who's depressed and who will not eat
|
mirtazapine
antidepressant that stimulates apetite |
|
weight gain (increased apetite) and dry mouth
|
mirtazapine
|
|
depression + insomnia
|
trazadone
|
|
leads to sedation, nausea, postural HoTN and priapism
|
trazaBONE
trazadone (inibits serotonin uptake [not an SSRI]) |