Psych Drugs

Front 1

Name All 7 TCAs

Back 1

imipramine, amitriptyline, desipramine, nortriptyline, climipramine, doxepin, amoxapine

Hint 1

S/E: NE reuptake (tremor, insomnia), cardiac fast Na+ channels (conduction defects, arrhythmias, hypotension), central and peripheral muscarinic AChR (opposite of DUMBBELSS), peripheral alpha1 receptors (orthostatic hypotension), histamine receptors (sedation)

Front 2

SSRIs

Back 2

Fluoxetine, paroxetine, sertraline, citaliopram

Hint 2

S/E: GI distress, SEXUAL DYSFUNCTION, serotonin syndrome (hyperthermia, muscle rigidity, cardiovascular collapse, flushing, diarrhea, seizures)

Front 3

SNRIs

Back 3

Venlafaxine, Duloxetine

Hint 3

S/E: increased BP, stimulant effects

Front 4

MOAi

Back 4

Phenelzine, tranylcypromine, isocarboxazid, selegiline (selective MAO-B)

Hint 4

S/E: hypertensive crisis w/ tyramine foods, CNS stimulation, contraindicated w/ SSRIs or meperidine

Front 5

Buproprion

Back 5

MOA: increases NE and dopamine via unknown mechanisms

Hint 5

S/E: stimulant effects, headache, seizure in bulemics, no sexual side effects

Front 6

Mirtazapine

Back 6

MOA: presynaptic alpah2 antagonist (releases NE and 5-HT) and also potent 5-HT2 and 5-HT3 receptor antagonist

Hint 6

S/E: sedation, increased appetite, weight gain, orthostatic hypotension

Front 7

Trazodone

Back 7

MOA: inhibits 5-HT uptake

Hint 7

S/E: sedation, nausea, priapism, postural hypotension

Front 8

High potency antipsychotics

Back 8

Haloperidol, fluphenazine, trifluoperazine, pimozide

Hint 8

More neuro side effects, less ACh and histamine side effects

Front 9

Low potency antipsychotics

Back 9

chlorpromazine, thioridazine

Hint 9

More ACh and histamine side effects, less neuro side effects

Front 10

Atypical antipsychotics

Back 10

clozapine, olanzapine, risperidone, aripiprazole, quietapine, ziprasidone

Hint 10

fever extrapyramidal and ACh side effects compared to antipsychotics. Olanzapine and clozapine induce weight gain. Clozpaine = agranulocytosis