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4 Cards in this Set
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Dementia dx
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Multiple cognitive defects.
Must have amnesia with one of the following: APhasia, apraxia, agnosia, disturbance in exec functioning. And these must cause social/occupational impairment. |
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Most common dementia
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Alzheimer's
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How is dx of Alzheimer's made?
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Clinically!
History, exam, r/o other things. Can only make 100% definite dx at autopsy. |
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Tx of AD
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Cholinesterase inhibitors (Donepezil, rivastigmine, galantamine)
NMDA receptor antag (Memantine) - due to glutamate excitotoxicity seen in AD |