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4 Cards in this Set

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Dementia dx
Multiple cognitive defects.

Must have amnesia with one of the following:
APhasia, apraxia, agnosia, disturbance in exec functioning.

And these must cause social/occupational impairment.
Most common dementia
Alzheimer's
How is dx of Alzheimer's made?
Clinically!

History, exam, r/o other things.

Can only make 100% definite dx at autopsy.
Tx of AD
Cholinesterase inhibitors (Donepezil, rivastigmine, galantamine)

NMDA receptor antag (Memantine) - due to glutamate excitotoxicity seen in AD