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187 Cards in this Set

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Gerontology
– the study of biological, psychological and social aspects of aging
Geriatrics
study of prevention and management of diseases of aging.

Focus on medical problems
Percentage of Adults in Nursing homes
only 5% of 65 & older but 25% of 85 and older
Life expectancy; male vs. female
Female 82.0


Male 74.2
Six leading causes of Death
1 Heart Diseases
2 Cancer
3 Cerebrovascular disease (stroke)
4 Lower respiratory disease
5 Alzheimer’s
6 Diabetes
Ageism
“prejudice and discrimination against older adults simply because of their age”

Everyone regardless of ethnic or social background
Life expectancy; white vs. black
Males 75; all 76; white 70; black

Females 80; all 81; white 77; black
Psychosocial Stressors
retirement
social isolation
loss of independence
low income
sense of lack of productivity
caregiving burdens
chronic illnesses
Generational cohort
aggregation of individuals who experience the same event within the same time interval
Life-span Perspective
age related changes in behavior throughout life; development never stops
Six Key Perspectives on Life-Span Development
1. Development is a lifelong process
2. Development includes both gains and losses
3. Development is multi- dimensional, directional & causal
4. Development is plastic
5. Development is embedded in historical, cultural and social contexts
6. Development is a multidisciplinary field
Plasticity
within limits, an individuals development is modifiable, based on life experiences; "actual development" causal outcome
Biopsychosocial Model
identifies biological, psychological, and social factors as interralated influences on health and illness
Normative Age-graded
– predictable, universally experienced events closely tied to an individual’s age. (e.g., puberty)
Highly similar across individuals and cultures.
Normative History-graded
influences that are a result of events occurring during a particular historical era. (e.g., war)
A group of people who experience the same historical events are somewhat similar.
Cohort – group born at similar time.
Cohort Effect – effect of year of birth.
– experiences that are unique or contribute to uniqueness in development. (e.g., immigrant status, serious illness)
Non-normative Influences
Psychology of aging is data rich but theory poor; true or false?
TRUE.
The Psychology of the Aged
Focus on older people and later life (> 65yrs.)
The Psychology of Age
Focuses on age differences
The Psychology of Aging
Focuses on age-associated changes
Primary aging
changes intrinsic to the aging process that are ultimately irreversible
-Slowness is the most common feature of primary aging


slower information processing speed
Secondary aging
changes caused by illness that are correlated with age but are preventable or reversible

1. Aging is a disease
2. Aging and disease are distinct processes
3. Relationship between aging and disease forms a continuum

Secondary Aging: chronic disease (cancer, CHD)
changes that occur precipitously in old age

“Complete shut down of body systems”

-pervasive process of deterioration
Tertiary Aging
Largest ethnic minority group of OA
African Americans
Poorest segment of OA
Native Americans
Being both old and a member of an ethnic minority group places individual at a
psychosocial disadvantage
. Naturalistic Observation/Field Method
Behavior in real-life settings (the field)
Less artificial
No control/manipulation
Complex observation
Observer fatigue a problem
Self-Reports: Interviews, Surveys & Questionnaires
most commonly used

Set of questions pertaining a subject’s attitudes, beliefs, behaviors or experiences
Lots of information from a large group
Quality of questions affects validity
Answers depend on subject’s honesty
Faulty memory, social desirability
Case Studies
In-depth investigation of one individual
Great deal of information is gathered
Much of information is retrospective

Study involves only one individual so lack of generalizability
reliabilty and validity
get it
correlational
experimental
cross sectional
longitudinal
sequential
Strongest design
Minimizes confounding of age, cohort & time
random events & 5 major theories
unpredictable insults from the environment (e.g., mutations)

Cross-Linking Theory
Wear and Tear Theory
Free Radical Theory
Rate of Living Theory
Somatic Mutations Theory
programmed events
events that are biologically determined to occur (e.g., decline in immune function)
skin protein collagen  wrinkles
eye lens proteins  cataracts
artery walls  atherosclerosis
cross linking: Inappropriate attachments in our proteins, DNA and other structural molecules (cross-linking)
Years of damage to cells, tissues & organs eventually wears them out, killing them & the body

Damage begins at the molecular level (DNA) from toxins, radiation & ultraviolet light
wear and tear
Mutations or spontaneous changes in our genes
Somatic Mutations Theory
Random events sufficient to explain aging; true or false
false; NOT sufficient
pacemaker theory
Based on a “Biological Clock”

Body systems set at birth to run for a period of time, then wind down, leading to aging and death

Two body systems most often suggested:

Neuroendocrine System
Immune System
Complex connections between brain and nervous system and our endocrine glands

Hypothalamus  Pituitary  Glands  Hormones

With aging, _______ function decrease and lead to:

increased BP
Impaired sleep, impaired sugar metab.
Neuroendocrine System
Programmed Events Theories:
Immune System
Key immune cells decrease as we age

T-cells and to a lesser degree B-cells decrease with age
Programmed Events Theories:
Genetic Theory
Lifespan is predetermined by genes we inherit

Evidence includes consistent life expectancy across members of a specie, females live longer

Long-lived parents --> long-lived children

-external forces can affect our genes

Families with high numbers of centenarians
Which Aging Theory Wins?
that a combination of genetic and random events is responsible for aging.

Any single limited theory of aging is certain to be insufficient.
Cutting caloric intake by __% is the only approach that has longer longevity in worms, mice and insects
30%; “Undernutrition without malnutrition”
Telomeres; is there a genetic clock for aging?
tips of chromosomes that contain repeating sequences of genetic material
- tips shorten every time the cell divides

When telomeres reach a critically short length, cell can no longer replicate

Biological clock genetically predetermined to wind down
The Nervous System (NS) & Aging
CNS - Brain and Spinal Cord -> Peripheral NS: Somatic NS (Voluntary Muscles) and Autonomic NS (Involuntary Muscles) -> ANS: Sympathetic high energy fight or flight and Parasympathetic low energy Relax/Restore
Regulation of body systems for life support
(respiration, digestion, excretion, blood circulation)

Hypothalamus (know role)
Autonomic Nervous System (ANS)
Hypothalamus in Autonomic NS
mostly controls the function of the ANS (coordination and communication)

-Coordinates info form other systems
- Communicates with other parts of the brain
-responsible for fight or flight
-body’s response to stressful and energy demanding situations
- activiation releases norepinephrine
Sympathetic Nervous System
Effects of Aging on Sympathetic Nervous System
increase of norepinephrine (excitatory neurotransmitter) in older adults; SNS may be working to compensate for less responsive tissues
Effects of Aging on Parasympathetic Nervous System
Restorative process when body is at rest (slowing heart rate, blood from muscles to organs)
Acetylcholine – major NT of this system
major neurotransmitter of the parasympathetic NS
Acetylcholine
major neurotransmitter of the sympathetic NS
norepinephrine (excitatory neurotransmitter)
Age-Related Neuronal Changes
Once neuron dies, no regeneration

If changes occur rapidly with more severity—disease is often present
Two problems in differentiating normal vs. abnormal brain aging:
-Same changes occur in normal & abnormal
-hence, difficult to tie these changes to disease
What happens in Axon Terminals?
Release neurotransmitters
Who's job is it to transport impulse?
Axon
What do Dendrites do?
Receive Chem signals from other cells; progressive loss in #’s with age, some die and some grow
Neurofibrillary Tangles
axon fibers become twisted & form tangles
-large # leads to Alzheimers; age related change in Axon
Cell Body
Nucleus, cell activity
Granulovacuolar Degeneration
cell body age related change; spaces in the cell body called Vacuoles accumulate
- Mostly occurs in the Hippocampus (area associated with memory)
What is the area associated with memory?
Hippocampus
Neuritic (Senile) Plaques
remains of dead neurons collect around & form abnormal accumulation of hard tissue

- increase with old age; higher increase (accumulation) causes decrease in normal function
Once _____ dies there is no replacement
neuron
Plasticity Model
Dendritic growth & regeneration through life
Reactive process dependent on environmental stimulation (learning promotes dendritic growth)
Hypothesized Causes of Neuron Loss
—Lipofuscin Hypothesis
—Circulatory Deficit Hypothesis
Circulatory Deficit Hypothesis—
circulatory deficits lead to deprivation of blood supply leading to cell death ; possible cause of neuron loss
Lipofuscin Hypothesis—
yellowish pigment in cell body interfering with metabolism leading to cell death ; possible cause of neuron loss
Age-Related Changes in the Synapse
Two opposing processes:
-Neuron death and synapse growth

- Age is not associated with change in number (neuron loss and synapse growth)
- Consistent with the plasticity model
-No universal loss of these neurotransmitters
-Some stability of the neurotransmitter in other areas
-Other neurotransmitters may compensate in the area of loss
-In general, the integrity of major brain pathways is maintained
_____________________ at the synaptic cleft forms basis for communication of info between neurons.
Release and re-uptake of neurotransmitters (NTs
Which are the Neurotransmitters?
Acetylcholine, Dopamine, Norepinephrine
involved in cholinergic pathway, associated with consolidation of short-term memory (Hipppocampus)

AGING effect: associated with decrease in cholinergic cells (Alzheimer’s
Acetylcholine
dopaminergic pathway of basal ganglia associated with motor movements

Aging – associated with decrease in dopaminergic cells
Dopamine
involved in postural balance, muscle tone, arousal and sleep

Aging associated with increase circulating nor-epinephrine -> sleep disturbance, arousal & decrease norepi pathways -> posture difficulties
Norepinephrine
Subcortical motor control structures 25% decrease in _______ (sensory info for movement)
Purkinje cells; decreases after 60
neuronal fallout in several key areas: visual, somatosensory, auditory—up to 50% (higher cognitive functn, judgment, analysis)
Cerebra Cortex
relatively intact BUT significant decrease (40% of neurons) in locus of coeruleus (sleep, arousal
Brain Stem
The reason for these changes (white matter in brain) is unclear, but it may be related to the normal _________________ in the brain with age
slowing of information processing
The_________ is a communication channel for the brain's information processing gray matter
white matter
The memory center of the brain is?
hippocampus
Autonomic NS and Aging
Body Temperature Control
> 65—impaired ability to adapt to extremes
Body Temperature Control
Poor Responses to Cold Temperatures:
-Reduction in awareness of lower core body temp. (hypothalamic function?)
-Older women have greater protection to cold temp. (increase in Body fat, hormones?)

Poor Responses to Hot Temperatures:
Reduction in sweat gland production in OAs
Theories of Sleep
-Repair/Restoration
-Evolutionary/Circadian
Sleep allows for recuperation from physical, emotional, and intellectual fatigue.
Repair/Restoration
Sleep evolved to conserve energy and protect our ancestors from predators.
Evolutionary/Circadian
Stages of Sleep
Hypnagogic state, Non-REM, REM
“pre-sleep” stage marked by visual, auditory and kinesthetic sensations.
Hypnagogic state
rapid eyes movements, high frequency brain waves, paralysis of large muscles and dreaming
REM
Consolidation of new memories
Role in learning
Absent in lower mammals
REM sleep
People deprived of all sleep show greater time spent in non-REM sleep the next night.
Non-REM sleep
Strong relationship between quality of sleep and _______________.
psychological symptoms
Sleep patterns in Older Adults
After 30 for men, 50 for women, decrease efficiency
-increase time spent awake in bed
-increase time needed to fall asleep
-Men more likely to suffer from disturbances
-increase disruption in REM
increase in norepinephrine might be the reason for
restless sleep patterns in older adults
Behavioral issues and sleep patterns
spend more time in bed to achieve rest, change in habit (go to sleep earlier), Maladaptive patterns in response to altered daily schedules or misconceptions about age-related sleep needs
What are the Effects of Sleep Deprivation?
Reduced immunity
Mood alteration
Reduced concentration and motivation
Increased irritability
Lapses in attention
Reduced motor skills
-Protect cells from harm by foreign substances
-Implicated in aging (Programmed/Pacemaker)
The Immune System
What is Immunosenescence?
Impairment of several lymphocyte activities associated with aging leading to a state of immune dysregulation.
Aging is associated with a progressive and irreversible decline in immune function; true or false?
true; but some function maintained
Immune System functions
NK cells ->preserved
Humoral B-Cells -> compromised functions, decrease in antibodies
cell-mediated T-cells (cytokines, lysis) ->some preservation, decrease in proliferation
Depressive Illness (decrease in lymphocyte proliferation)
Bereavement (decrease in lymphocyte proliferation, decrease in NK cytotoxicity)
Caregiving (decrease in T-lymphocytes, increase titers to EBV)
Personality, Stress and Coping
Alcoholism
psychosocial factors & immunity
psychological stress and immunity
negative events and stress -> negative thinking, depression ->Inflammatory cytokines, NK cytotoxicity, CTLs response
One of most noticeable changes of aging
(after processing speed, physical appearance, vision/ hearing & mobility
Cardiovascular Function
developmental forces interact (lifecycle)
Biological—genetic links, strong component

Psychological—personality (hostility), depression

Socio-cultural—diet, exercise
pumps blood continuously through circulatory system to provide blood/nutrients to cells; age-related changes limits ability to pump blood to cells
heart
2 Major Significant Structural Changes in heart & arteries
-Contractility of left ventricle wall thus decrease ejection
-Arteries become rigid and narrow—less blood flow
Largest chamber—pumps blood to aorta
-Interior wall becomes thicker
-Cell death, decrease elasticity (more rigid)
-decrease in muscle tissue, increase fat & connective tissue
- During emptying of ___, muscle contract less and eject less blood
Left Ventricular (LV) Contractility
-emptying phase
-contraction
Systolic Phase (HBP
-filling phase
-expansion
Diastolic Phase (LBP)
Rigidity & Narrowing of Arteries
less ability to distribute blood
Atherosclerosis (age-related changes in arteries)
arteries become rigid and narrow by fatty accumulation (artery damage)

Aging -> more circulating lipids
Immune System -> more inflammatio
Aorta (age-related changes in arteries)
becomes less flexible so greater resistance for blood leaving the LV
What are some Consequences of changes in cardiovascular function?
- decrease cardiac output (max. amount of blood delivered from heart to body tissue/minute)

- decrease maximum heart rate (O2 consumption);-Index of inefficient function

- Increase blood pressure—some debate; -Younger individuals w/o these changes can have high BP
-Heart muscle cells receive insufficient O2 due to blockage of arteries

-Most common in older adults
-12% of women, 20% of men
-Can lead to congestive heart failure
Ischemic Heart Disease

type of Cardiovascular Disease
-Irregularities in heart beat
-Extra, uneven heart beats
-Fibrillation—very rapid & irregular contractions
-Cause unknown
-Can lead to sudden death
Cardiac Arrhythmias

type of Cardiovascular Disease
-Build-up of fat deposits on arterial wall
-Leads to calcification of wall
-Blood clots can get “stuck” and block flow
-These blocks cause heart attacks


?angina
Atherosclerosis

type of Cardiovascular Disease
Chest pain associated with lack of blood flow and O2 to the heart
Angina

type of Cardiovascular Disease
-Blood flow drops below normal
-Cells in the heart muscle can die
-25% of cases no chest pain—this is more common in older adults
Myocardial Infarction

type of Cardiovascular Disease
-Lack of blood flow to brain due to artherosclerosis
-CVA (accident; CVA) or Stroke: complete cutoff of flow to a brain area
-Range in severity from unnoticed to severe impairment
Cerebrovascular (CV) Disease

type of Cardiovascular Disease
as we age blood pressure increases; if it is severe..what is the diagnosis?
Hypertension (HPTN)

type of Cardiovascular Disease
respiratory system
-Confounds: smoking, pollution, infection
-Interaction of aging & environment
Rib cage and air passageways -> stiffer
- decrease CO2 -> O2 exchange
-By age 85, 40% decrease lung capacity
-Lead to shortness of breath during physical exertion
respiratory system and aging
-Smoking & Pollution are major causes
-Bronchial tubes become blocked
-Abnormal tissue develops
Chronic Obstructive Pulmonary Disease (COPD)

type of Respiratory Disease
-Air sacs are destroyed
-Irreversible, no CO2  O2 exchange
-Very debilitating
-Caused by smoking
Emphysema

type of Respiratory Disease
shortness of breath and psychological consequences
-Can be very frightening
-Some unnecessarily withdraw from phys act
-Lower sense of competence and well being
Aging is not associated with deterioration of sensory systems (taste, smell, touch, vision & hearing); true or false
false; Senses become less acute—trouble distinguishing details
Vision and age
1. Changes in the structure of the eye
2. Changes in the cornea & retina
Eye structure aging effects
Cataracts—spots develop in the lens

-Glaucoma—improper drainage of fluid in the eyes -> increase IO pressure & loss of vision
cornea and retina
Cornea: Becomes less sensitive to light

Retina:Contains receptor cells (rods & cones)
progressive irreversible destruction of receptors
Macular degeneration
a clouding of the natural lens, the part of the eye responsible for focusing light and producing clear, sharp images.
cataract
Which ear structures deteriorate?
-Ear drum thickens; most common damage
-Inner ear bone deteriorates

* noise more affective than aging against hearing
How is balance is controlled in the inner ear
Fluid & small hairs in semicircular canal stimulate nerves for balance
difficult in hearing high pitch noises due to changes in inner ear
Presbycusis
Complaints with tasting food related to loss of capacity in smelling
smell-> rapid decline after 60's, tase -> Ability to detect tastes gradually decrease, decrease in saliva; dry mouth, swallowing difficult
What Accounts for Decreasing Sexual Activity with Age?
lack of partner, men and medical issues, widow, partner illness,
Changes in Physical Functioning with Age - Men
-Longer to get erection
-Erection less firm (only complete at orgasm)
-More rapid loss of erection after orgasm
-Less ejaculatory power
-Less rectal and ejaculatory contractions
-Longer resolution period
Changes in Physical Functioning with Age - Women
-Change in the shape and flexibility of vagina
-Decreased vaginal lubrication
-Less clitoral and labia swelling
-Less or lost breast engorgement
-Less rectal and orgasmic contractions
-Emotional problems/stress
-Urinary tract symptoms
-Ever being forced to have sex
-Being sexually touched before
puberty

all related to:
arousal disorder
Medication
Oral
Transurethral
Penile Injection
Vacuum Pump
Prosthesis
treatments for erectile dysfunction
Type A Personality
Competitive, angry, hostile, aggressive, impatient

Are 2x’s as likely to develop CVD
but recover better
Type B Personality
opposite of A
Older adults average __ diseases and fill about __ prescriptions per year.
3.5 ; 13
Psychological Interventions
Personal (Coping)
Medical (Doc-Pt. Relat.)
Social (Support)
Life Stress (Stressors)
Quality of Life
(Physical) (Psychological) (Social) (Vocational) (Sexual)
Survival
Number of persons in support groups is growing; true or false
true; reasons can be for Job mobility, retirement relocation
What rargets CD4+ T-lymphocytes?
Human Immunodeficiency Virus
HIV/AIDS Medications
18+ antiretroviral pills/capsules, prophylactic meds. & vitamins resulting in 6 daily med. times
Poor adherence associated with rapid development of resistance seen after only __ days of missed dosages
3
psychomotor speed
(reaction time) only universally accepted behavioral change yet discovered

-reflects outcome of sensory memory and attention memory
divided attention
the ability to successfully perform more than one task at the same time

older; more difficulty diving attention among tasks ->complex tasks, not simple
simple reaction time
most used; responding as quickly as possible; hitting a bar when red is shown

slower simple for older adults
Making separate responses to separate stimuli as quickly as possible ; hit left or right bar dep. on color
choice reaction time
most sig. age related differences

complicated decisions on how to respond based on info presented (driving)

men have greater speed...don't know why
complex reaction time
neutral networks theory
age-related neuronal loss (takes more neurons to make decisions)
information loss model theory
more info lost as each step of processing (feature extraction, encoding; how we percieve) than for younger adults (deficits in sensory and attention memor)y
memory
acquisition, storage, retrieval of information. A memory involves patterns of neuronal activity.
Where new incoming info is first registered
Involves vision, hearing and touch
-info from senses to CNS
sensory memory
working memory
info temporarily available and active
info held for a period of time ranging from minutes to a lifetime

*most problems we see are in sensory memory and attention memory
long term memory
components of working memory
phonological, visuospatial, central executive

deficit adults: 2nd digit from a serious of additions 2+(3) 5-(2)
speech based info, articulation of information (working -> long term) repeating info

deficit: sensory deficits (vision, hearing), reduced processing speed ,deficit in inhibition of irrelevant info ->mental clutter
phonological store
manipulate and maintain visual and spatial images (org. to store into long term) learning directions

deficit: sensory deficits (vision, hearing), reduced processing speed ,deficit in inhibition of irrelevant info ->mental clutterpad
visuospatial scratch
central executive
decides how to allocate cognitive resources (rehearse a name, form mental street map)
episodic memory
memory for events (word lists)

recall from a list of words
working memory
semantic memory
knowledge (definitions, historical facts)

deficit: complex definitions
no difference in simple word def.
working memory
procedural memory
how to perform activities

implicit - info acquired unintentionally
explicit - conscious attempt to learn
working memory
long term memory (check slides)
slides
slides
intelligence
combination of tasks to learn new info, perform new task, adapt to new challenges, and be creative

indiv. mental ability overall

defining factor of identity
remains stable over time
intellgence and older adults
emphasis on defining factor of identity
-->become more vigilant of age-related decrements in intellectual functioning

more difficult dealing with very subtle changes that dont make much of a differnece to most individuals
two main categories in intelligence
verbal and nonverbal intelligence
Thurstone and Mental Ability Theory
verbal meaning. word fluency, number, spatial relations, memory, perceptual speed, general reasoning
bone problems
1. osteoporosis (women *biophosphonates help* susceptible; leading cause of broken bones, late 50's), 2. osteoarthritis (bones under cartilage damaged; athletes, manual laborers; hands, spine, hips, knees) 3. rheumatoid arthritis (severe disease of joints)

arhtroplasty - total replacement of joints
fluid crystallized theory
secondary mental abilities: fluid intelligence & crystal intelligence
crystal intelligence:
skills and information acquired thru experience and formal education -> knowledge, judgement, historical facts, word definitions

increase over time
fluid intelligence
- innate ability to integrate and analyze new info ->inductive reasoning, responding to new situations, mazes, puzzles

(on going stimulation->helps brain)
decrease over time
individual intelligence differences
health, rontal lobe function, gender (men better on numerical skills, generalized knowldge (crystallized) and spacial orientation, women do better on fluid tasks such as digit symbol, a task requiring close attention to detail)
personality and intelligence
self-efficacy creates env. and drive to succeed
rigidity-flexibility
cognitive, psychomotor, and attitudinal flexibility
personality characteristics and intelligence
realists - accurate declines

optimists - underestimated changes in decline -> denial? had most declines

pessimists- overestimated losses -> increased performance or showed no changes...took protective action, compensating?
50 items, MC, 2 EC

focus on notes and age related changes, study guide sections and major concepts and findings

no names, dates, or specifics

people in nursing homes (ratio of men and women) life expectancy
intelligence and intervention
interventions can provide *SLIDES*
wisdom vs. intelligence
age alone does not foster wisdom

wisdom: awareness of a finite existence, role of culture in shaping people's life; higher level concepts not easily tested by conventional tests

provide insight, less likely to judge others, greater appreciation for indiv. diff. in value
manage uncertainty as a fact of life
tolerance of ambiguity
More CD4 T-lymphocytes are infected and destroyed

Impaired replacement of naïve CD4 T-lymphocytes

Less effective anti-HIV immune activity

Greater synthesis of proinflammatory cytokines
HIV in OLDER ADULTS;
(Greater risk of HIV/AIDS disease progression
Greater number of opportunistic infections
Lower CD4 T-lymphocytes
Shorter AIDS free intervals
Faster progression to AIDS
Higher mortality rates)
-Lower mortality rates among light drinkers
-Lower risk of _____ after controlling for smoking and other health habits
stroke; benefits of alcohol use
The Information Processing Model
Incoming info -> based on knowledge base -> stored
*
With greater base of knowledge -> more easily info is stored
Sensory Memory -> Attention Memory -> Working Memory -> Long Term Memory
4 stages of Information processing