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57 Cards in this Set

  • Front
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Why is your brain lying to you? w example

-what is expected and what is not


-what is thrown away


-expectations and reality are both at play



Example: pickpocketing. expectation to the area that is being touched vs The other side that is being robbed


Daniel Wolbrent TedTalk

Take Home:


-brain plans and executes


-need brain because we move

What is a large component of the planning phase of movement?

predictions


ex: milk carton

BCI - Brain Computer Interface

translate mental activity into movement


-employs electrical signals from brain to direct computer controlled devices

CBI - computer brain interface

employ electrical signals from computer to direct brain

What are the major components of the motor system?

Forebrain: planning and initiating



Cerebrum: conscious control of movement



Brain stem and spinal cord: automatic movements

In the face of impaired brainstem or spinal-cord function, the forebrain can _______ movements but can ______ produce them

imagine, not

Sequence of steps in organized movement

1. Visual info required - relayed to somatosensory regions of neocortex


2. motor region of neocortex plans and initiates movement


3. spinal cord carries info to the hand


4. motor neurons carry info to muscles of hand


5. sensory receptors on fingers send message to sensory cortex (cup has been grasped)


6. spinal cord carries sensory info to brain


7. informs motor cortex and basal ganglia judges grasp forces, cerebellum corrects movement errors


6. sensory cortex confirms the action

What is the only sense out of touch, taste, hearing and vision that we do not share with others?

Touch - it is internal, not shared, we have few descriptive words for it

Sensory humunkulous is...

a representation of the cortical real estate


-hands, lips, tongue --> very large


-ankles, wrists --> small

What is movement made up of?

Planned patterns, i.e Chunking


-small bursts of relate movements

What is chunking

it is small bits of related movement

How is a motor sequence initiated?

1. Prefrontal cortex plans complex behaviour sends instructions to the premotor cortex


2. premotor cortex sequences multiple actions


3. primary motor cortex executes actions


If an individual was no longer able to coordinate a set of tasks in order to complete a goal, what area of the forebrain would likely be damaged?

Premotor cortex: this area puts multiple actions in a sequence for complex behaviour

People who have difficulty shaping their fingers correctly to perform precision grips, likely have damage to what area of the forebrain?

The Primary Motor Cortex: this area specifies how movement will be carried out.

What are of the brain controls species-typical behaviours?

brainstem: actions displayed by every member of a species - pecking of robin, hissing of cat...etc.

Locked in syndrome

when an individual is aware and awake but cannot move or communicate verbally due to complete paralysis of nearly all voluntary muscles except the eyes.

"Grooming Sequence" illustrates how...

complex patterns of action are coordinated by brainstem

An important brainstem function is to produce complex patterns of adaptive behaviour including:

-eating, drinking and sexual behaviour


-grooming sequence


-maintaining posture, standing upright, -coordinating movement of limbs, swimming and walking



*simpler circuits

Damage of the brainstem can result in

Locked-in syndrome

What did the experiment of continued stimulation of the rooster demonstrate?

stimulation of brainstem sites produce behaviour that depends on context


-suggests important function of brainstem is to produce appropriate species-typical behaviour

Movement planning is relative to the _____ we have

goals

Our physical response time is limited by our _______ restraints

-physiological


-i.e axon, to axon, to axon speed

Movement control is....

-HIERARCHY: generated using multiple systems in the motor hierarchy (forebrain, brainstem, spinal cord)


-TANDEM: used in tandem


-GOALS: programmed around planned (prefrontal) control


-CHUNKED


What is the basic flow of movement from the brain?

1. motor cortex: preF, preM, primM


2. Corticospinal tract


3. spinal neurons


4. muscles

A humanukulus makes it useful to understand...

the topographic organization (functional layout) of the primary motor cortex

Motor cortex plasticity contributes to:

-recovery after motor cortex injury


-motor learning

Eyes in relation to movement: 4 movements of eyes to fixate on areas of interest

1. Saccade: jump from one point to another


2. smooth pursuit: following moving objects


3. Vergence: closer/further/closer - binocular


4. Vestibular-Ocular: adjust for head movement = produces image right side up

Corticospinal Tract: ventral vs. dorsal

Motor cortex --> brainstem --> spinal cord


ventral: motor


dorsal: sensory

What is the alt name for the corticospinal tract? why?

Pyramidal Tracts


-collection of axons descending into the brainstem create bumps --> "pyramids"

Crossover occurs in the cortiospinal tract. What % division occurs?

This division produces two corticospinal tracts - one crossed, the other uncrossed


90% from opposite side


10% from same side

Efference Copy

.

3 divisions of Somatosensory receptors


.....FINISH

1.Nocioception (pain, temp, itch)


2. Hapsis


3. Proprioception (body awareness)

Mirror Neurons

-a neuron that is active while you do something and while you watch it being done

What does it mean to say that muscles work in pairs?

.Extensor and Flexor


When flexor is excited (bicep) the extensor (tricep) must be inhibited

Skilled movements

-use dependent


-requires excitation of motor cortex


-use TMS to disrupt signal ...?


-the amount of activity can influence movement - amplitude


-the amount of cortical real estate is use dependent (activity is coded for, and takes up cortical real estate)


-blurred lines of neuron mapping i.e 2 fingers that are always used together

Motor Tract Organization

-Ventral and Lateral


-Ventral: core


-Lateral: away from midline of body to the side you are using


-Fingers, arms, shoulders, trunk (FAST response)


Cortical neurons --> interneurons --> motor neurons

What is the main efferent pathway from the motor cortex to the brainstem to the spinal cord?

the corticospinal tract

What is the path of the corticospinal tract?

1. from motor cortex (and some premotor cortex and sensory cortex)


2. axons descend into brainstem (creating pyramids)


3. cross over --> which produces two corticospinal tracts (ventral=trunk, lateral=sides)


4. dual tracts on each side of brainstem then descend into spinal cord --> forming 2 spinal cord tracts

corticospinal to muscles

1. corticospinal synapes with interneurons and motor neurons


2. interneurons project to motor neurons


3. motor neurons synapse on the muscles that control body movement

what is the NT at the motor-neuron-muscle junction called?

acetylcholine

In regards to movement, damage to the cerebellum does not abolish movement but does________

disrupt the timing and execution of movement


-however, with mirror neurons in mind - might be able to help ppl w damaged cerebellum learn tasks while talking them throught their actions.

What do mirror neurons tell us about how we understand the world?

we understand the world by engaging in it.

Actions are corrected in two ways

1. Basal Ganglia - "online control", error corrections while it is happening fI


2. Cerebellum - "offline control"', error detection

How does the basal ganglia help to correct actions?

-associated with error correction


-for errors that are happening while an action is being executed "online control"


ex: too much force, too much 'volume'

How does the cerebellum calculate the errors in your movement?

Through two versions of your planned movement:
1) intended movement (with a copy of movement sent to cerrebellum through interior olive/brainstem)


2) actual movement as recorded by sensory receptors


The cerebellum has info about both systems

How does the somasensory system impact movement?

without it, we would be impaired


-the soma system tells use what is going on in the enviro and what we are doing.


-it allows us to disginguish between what is done to us from what we do


(pushed vs lunged to the side yourself)

If the basal ganglia was damaged, what types of disorder could occur?

-number of disorders that can occur


-Huntingtons Kora - too much output (milk carton)


-hypoconnetick - too little output


-tourette's syndrome

Error correction vs error detection

EC: Basal Ganglia - 1) output of force, 2) predicitons "online errors"


ED: cerebellum has 1/2 of the motor neurons


*Large contribution Smoothes out movement. "Offline errors."


Lat and Medial - FAST

hyperkinetic vs hypokinetic

hyper: too much force


hypo: to little force


(disruption of basal ganglia)

What were the takehome messages from "Feedback Video - Ian"

-no proprioception (where body is in space)


-relied on eyes to tell brain what body was doing



Feedback is essential and we are never aware of how this info is coming in ALL THE TIME

What are the three somatosensory receptor categories?

1. Nocioception: irritation: pain, itch and temp


-Free nerve endings = slow


2. Hapsis (fine touch/pressure ex vibration)


-meissner's, pacinian, ruffini corpuscle = rapid


-merkel, hair = slow


3. Proprioception: (body awareness ex: stretch)


-muscle, golgi, joint = rapid

rapidly adapting receptors vs slowly adapting receptors

rapidly: respond to beginning and end of a stimulus and produce only breif bursts of APs



Slowly: continue to respond as long as a sensory even is present -

to somatosensory pathways to the brain

1) haptic-proprioceptive (touch and body awareness) = ipsilat


2) nocioceptive (pain, temp, itch) = contralat

Motor adaptation requires (2)

-prediction (copy sent to cerebellum via the inferior olive)


-error comparison (online - basial, or offline - cerebellum)


apraxia vs ataxia vs aphasia

-disorder of motor planning


-a lack of coordinated movements


-inability to produce (broca's)/comprehend speech (wernicke's)

Broca's vs Wernicke's

Broca's: produce speech


Wernicke's: comprehend