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42 Cards in this Set

  • Front
  • Back

Antigen

"Foreign" particle (protein portion) elicits immune response

B-cells

make specific antibodies (proteins) that attach to and attack specific antigens

Natural killer Cells

(blood cells) non-specific killing of antigens (and tumor cells)

Macrophages

remove waste, cause inflammation

psychosomatic

Real illness brought on by neg psych state

hypochondria

paranoid about having illness

malingering

fool doctor

munchausens

making self sick

Phineas Gage

Railroad accident--> severed connection between frontal cortex and limbic system-->Acted emotional

Endocrine

hormone that secrets into blood (global)

Exocrine

Hormone that secrets locally

Gonads

endocrine part of reproductive organs


-secrete sex hormones


-produce/release gametes

genitalia

non-endocrine part of reproductive organs

Types of Hormones

Steroid:


-diffuse across cell membrane


-attach to receptors in cytoplasm


-triggers gene expression (days)




Protein/peptide & AA Derivative


-attach to receptor on cell membrane


-activate 2nd messenger sys inside cell


-alters metabolism of cell (min or hours)

Types of Steroid hormones

-Cortisol




-Sex hormones

Types of sex hormones

-Androgens->TTT




-Estrogens->Estradiol

Female Masculinization (Intersexes)

Genetic Female but TTT in utero


A) Adrenal Cortex gland


-exs steroids->exs TTT


B) Anti-miscarriage drug->mimics TTT



Testicular Feminization

Genetic Male but insensitive to TTT in utero




appear female but have male gonads->No menstral cycle

Levay Study

Found homosexual males with larger SDN


Controversial because all brains had HIV




-Non-HIV->Not significant

Retention

maintaining a memory

recall

to bring back to mind, to retrieve

recognize

to perceive something as previously known, familiar

STM

-Memory for things that just happened


-limited storage 7 items (-/+ 2)

LTM

-Memory for things that do not currently occupy your attention


-must be recalled/recognized

Explicit Memory

'Semantic'


memory for events/facts


'episodic' memory (events) -->"remember"


'declarative' mem (facts) --> know

Implicit Mem

memory that doesn't require recollection of specific events/facts, yet affects out behavior


1) Learned motor skills


2) Priming effects


-word priming: recognize word if first is


actual word-->almost subliminal


-Subliminal adverts


3) Conditioned Response

Operant Conditioning

If you do this, I'll do that

Conditional conditioning

When I do this, you'll do that


Capitalizes on natural response

Retrograde amnesia

loss of events prior to injury

anterograde amnesia

inability to create new memories after the injury

Receptors for Glutamate

1) AMPA: When glute binds to it, AMPA lets in Na+-->Depolarizes neuron




2) NMDA: When glute binds to it, and if neuron is depolarized (AMPA), NMDA lets in Ca2+

Habituation

Withdrawal resp gets less intense over time

Non-hebbian learning

Learning not based on synapses strength, instead NT depletion

Hebbian learning

learning must be a change at synapse

Hebbian Mechanisms

increase in synaptic strength (connectivity) btwn Pre and post synap neuron when two neurons are active simultaneously




'Neurons that fire together get wired together'

Aphasia

Left hemisphere damage

Language is LH, then how does the RH work? (3)

Connections btwn hemispheres


1) Corpus Callosum (massive)


2) Anterior commisure (connects part of frontal cortex)


3) Hippocampal commisure (connects hippocampi)

LH specialized for

local visual processing


-analytical, sequential

RH specialized for

global visual processing


-creativity


-facial expressions of emotion

Broca area (LH)

Frontal lobe


-problems with syntax and completed sentences


-less trouble with nouns, verbs->semantics




Syntax impaired, semantics okay

Wernicke area (LH)

Temporal lobe


-trouble with comprehension


-can speak fluid sentences


-speak gibberish

Why were the patients laughing or angry during the presidents speech? (Oliver Sachs)

RH damage, Angry->couldn't understand prosody




LH damage, laughing->couldn't understand sentences, syntax but understood tones and exaggerated gestures




Without LH, could be tricked