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63 Cards in this Set

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What are the types of eating disorders?
- Anorexia nervosa
- Bulimia nervosa

- Binge eating disorder
- Avoidant / restrictive food intake disorder

- Other specified eating disorder
- Unspecified eating disorder
Case 1:
- 16 yo Caucasian girl w/ history of depression and anxiety (treated w/ SSRI)
- Parents are concerned about weight loss
- Started dieting 6 months ago: initially cut out snacks, limits desserts, and started running; started avoiding fats and carbs; only eats 200-500 calories/day
- Insists on prepping her own food and makes elaborate food for others
- Isolated from friends and avoids situations involving food
- Lost 20 lbs and BMI of 16, wants to lose 10 more lbs
- 4.0 GPA wants to go to med school, figure skater, active in school clubs
- No interest in dating, not sexually active, no alcohol/drug use
- Fam Hx: mother has anxiety, aunt has eating disorder
- Last menstrual period 6 months ago

What is the diagnosis?
a) Disordered eating
b) Eating disorder not otherwise specified
c) Anorexia nervosa
d) Obsessive compulsive disorder
e) Avoidant/restrictive food intake disorder
Anorexia Nervosa
What does "anorexia" mean?
Loss of appetite (but this is not true of anorexia nervosa - they do have an appetite)
What characterizes Anorexia Nervosa?
Disturbance in body image and intense pursuit of weight loss
What are the DSM IV diagnostic criteria for Anorexia Nervosa?
• A. Weight loss to less than 85% of ideal body weight or failure to make expected weight gains in children and adolescents
• B. Intense fear of gaining weight
• C. Disturbance in how one perceives their
body
• D. Amenorrhea for 3 months in postmenarcheal females
What are the changes to DSM 5 for the diagnostic criteria for Anorexia Nervosa?
• A. Removal of less than 85 percentile of IBW criteria → “significantly low weight”
• B. Intense fear of gaining weight or behaviors that interfere with weight gain
• C. Unchanged
• D. Removed the amenorrhea criteria
What are the subtypes of Anorexia Nervosa?
- Restricting type
- Binge-eating / purging type
What are the signs of the Binge/Purge type of Anorexia Nervosa?
• Eating a large amount of food in a short period of time
• Engaging in compensatory behavior to get rid of the food or weight
• Feelings of loss of control during the episode
Why is Anorexia Nervosa so important to diagnose?
It is the most lethal psychiatric disorder (don't ignore weight loss in teenager patients)
What are the physiologic effects of starvation?
Vital sign changes
– Hypotension
– Bradycardia
– Hypothermia
How do you treat Anorexia Nervosa?
Refer patient for inpatient medical stabilization
Which organs are affected by Anorexia Nervosa?
• Dermatology: Lanugo (fine baby-like hair over the body)
• Cardiac: Syncope, arrhythmias and sudden death
• Endocrine: Cold intolerance, amenorrhea
(decreased LH, FSH, and estradiol)
• Hematologic: anemia, leucopenia
• Skeletal: Osteopenia/Osteoporosis
• Neurologic: Reduction in brain mass volume and cognitive deterioration
What happens dermatologically in Anorexia Nervosa?
Lanugo (fine baby-like hair over the body)
What are the cardiac changes in Anorexia Nervosa?
Syncope, arrhythmias and sudden death
What are the endocrine changes in Anorexia Nervosa?
Cold intolerance, amenorrhea
(decreased LH, FSH, and estradiol)
What are the hematologic changes in Anorexia Nervosa?
Anemia, leucopenia
What are the skeletal changes in Anorexia Nervosa?
Osteopenia/Osteoporosis
What are the neurologic changes in Anorexia Nervosa?
Reduction in brain mass volume and cognitive deterioration
What happens when a patient with Anorexia Nervosa starts getting refed?
Refeeding Syndrome:
- Syndrome of clinical complications that occur as a result of fluid and electrolyte shifts during nutritional rehabilitation of severely malnourished patient.

- Refeeding too quickly can lead to hypophosphatemia and potentially life threatening arrhythmias.

- Risk of refeeding syndrome is directly related to the amount of weight lost during the current episode and the rapidity of weight restoration.
How is most commonly affected by Anorexia Nervosa?
- More often in females
- 10% in males
- Usually onset is in mid-teens, though recent trends towards pre-pubescent development
- 1% of population w/ 5% showing subclinical signs
What causes Anorexia Nervosa?
Multifactorial
- Different in every patient
- Dieting is #1 risk factor
- Biopsychosocial formulation
Multifactorial
- Different in every patient
- Dieting is #1 risk factor
- Biopsychosocial formulation
What are the biological factors contributing to Anorexia Nervosa?
• Higher rates in monozygotic twins
• Strong family history for mood disorders
– Biochemical changes (norepinephrine, endorphin
increases, starvation effects)
• Associated with onset of puberty
What are the psychological factors contributing to Anorexia Nervosa?
• Temperament – perfectionist, harm avoidant
• Maturation fears
What are the social factors contributing to Anorexia Nervosa?
• Media influence
• Obesity education (need to emphasize health not weight)
• Family concerns about weight
• Dieting information
• Teasing about weight
• Performance pressures in sports
Who are the components of the team that treats a patient with Anorexia Nervosa?
- Primary care physician
- Psychiatrist
- Dietician
- Family therapy, individual therapy, group therapy
Which meds can help treat Anorexia Nervosa?
• No medications have consistently shown benefit for the core symptoms of eating disorders (ED)
• Medications are generally used to treat psychiatric comorbidities
What are the approaches to therapy used to help patients with Anorexia Nervosa?
• “Maudsley” Family Based Treatment (family is in control of what patient eats)
• Cognitive behavioral therapy (CBT) to address cognitive distortions
• Dialectical behavioral therapy (DBT) to address treatment interfering behaviors
Case 2:
- 21 yo college female presents w/ spells of binge eating followed by obsessive need to rid herself of calorie she just ate
- Behaviors include self-induced vomiting, excessive exercising, and using diet pills and laxatives
- Previously 20 lb overweight but currently at a normal weight, although she believes she is very overweight
- Swollen cheeks and abrasions on her left knuckles

What is the diagnosis?
Bulimia Nervosa
What does "Bulimia Nervosa" mean?
Voracious appetite or constant hunger, again a misnomer because it is characterized by episodes of overating and compensatory behavior to prevent weight gain
What are the DSM-IV criteria for diagnosing Bulimia Nervosa?
• A. Recurrent episodes of binge eating followed by inappropriate compensatory behavior in order to prevent weight gain
• B. Episodes occur at least twice a week for 3 months
• C. Self evaluation is unduly influenced by body shape and weight
• D. The disturbance does not occur exclusively during anorexia nervosa

• Subtypes: purging type and non-purging type
What is considered purging?
a) Restrictive dieting/skipping meals
b) Binge-eating
c) Nausea
d) Routine exercise
e) Laxatives
Laxatives
(also diuretics, enemas, vomiting)
What are the changes to DSM-5 criteria for diagnosing Bulimia Nervosa?
A. Recurrent episodes of binge eating
B. Recurrent inappropriate compensatory behavior in order to prevent weight gain
C. Episodes of A and B occur at least once a week for 3 months
D. Self evaluation is unduly influenced by body shape and weight
E. The disturbance does not occur exclusively during anorexia nervosa

• Subtypes were removed
• Severity can be specified: based on number of episodes/week
What are the clinical signs of Bulimia Nervosa?
• Swollen cheeks
• Russel’s signs: abrasions on knuckles from scraping against teeth
• Front teeth that are chipped or ragged and “moth-eaten”
• Dental erosions and caries
• Damagetotheesophagus
• Cardiac arrhythmias and myopathies
• Fluid and electrolyte imbalance
Why do patients with Bulimia Nervosa have swollen cheeks?
Parotid gland hypertrophy or infection
What is Russel's sign?
Abrasions on knuckles from scraping against teeth
What signs would you expect on the teeth of a patient with Bulimia Nervosa?
- Front teeth: chipped or ragged and "moth-eaten"
- All teeth: erosions and cavities
What are common laboratory abnormalities associated with purging?
a) Serum glucose abnormalities
b) Low serum amylase
c) Hypernatremia
d) Hypokalemia
e) Hyperlipidemia
Hypokalemia
What are the most common abnormalities associated with vomiting?
- Metabolic alkalosis (low potassium, low sodium, elevated bicarbonate)
- Hypokalemia
- Hypochloremia
- Hyperchloremic metabolic acidosis (low potassium, elevated chloride, low bicarbonate) due to laxative use
- Elevated serum amylase level
- No significant blood sugar abnormalities
- The highest levels of cholesterol are in patients with anorexia who also binge-purge
Which Eating Disorder patients have the highest levels of cholesterol?
Patients with anorexia who also binge-purge
What are the implications of hypokalemia in patients who excessively vomit?
Excessive vomiting leads to loss of K+ → potentially lethal arrhythmias
How should you treat patients who are purging more than 3x/day?
Refer for inpatient evaluation (may have metabolic abnormalities)
How common is Bulimia Nervosa?
- More common than Anorexia Nervosa (>3% of population)
- Onset is later than Anorexia Nervosa (lat adolescence / early adulthood)
- Surveys of college women found up to 40% report binging and purging
How can Bulimia Nervosa be treated pharmacologically?
- More responsive to serotonin fluctuations
- SSRI antidepressant medications have been shown to be effective (eg, Fluoxetine)
What is the typical temperament of a patient with Bulimia Nervosa?
- Overachiever
- Competitive secretive
- Ego dystonic
- Self-critical
What behaviors / disorders is Bulimia Nervosa associated with?
- Depression
- Alcohol use disorders
- Impulse control disorders
- Emotional lability
- History of abuse
What are the social factors that contribute to Bulimia Nervosa?
- Media influence
- Anti-obesity education
- Weight teasing / bullying
How do you treat Bulimia Nervosa?
Meds:
- SSRI anti-depressants

Therapy:
- Cognitive Behavioral Therapy (CBT)
- Dialectical Behavioral Therapy (DBT)
- Family Therapy
- Group Therapy
What are the diagnostic criteria for Binge-Eating Disorder?
• A. Recurrent episodes of binge eating
– Eating in a discrete period of time more than most people would
– Sense of lack of control
• B. Binge eating episodes are associated with 3+ of
– More rapid eating, feeling uncomfortably full, eating large amounts of food when not feeling hungry, eating alone due to embarrassment, feeing disgusted/depressed/guilty after
• C Marked distress regarding eating binge eating
• D. Occurs once per week for 3 months
• E Not associated with recurrent use of inappropriate compensatory behavior, and not exclusively during bulimia nervosa or anorexia nervosa
• Same severity scale as bulimia nervosa
What are the diagnostic criteria for Avoidant / Restrictive Food Intake Disorder?
• A. Persistent failure to meet appropriate nutritional/energy needs with one of:
– Significant weight loss or failure to gain expected weight – Significant nutritional deficiency
– Dependence on enteral feeding or oral supplements
– Marked interference with psychosocial functioning
• B. Not better explained by lack of food or cultural practice
• C. Not part of anorexia nervosa or bulimia nervosa and not associated with a disturbance in the way one’s body weight/shape is experienced
• D. Not attributable to a concurrent medical condition or other mental disorder, or beyond what one would expect for another condition/disorder
What are the other specified eating disorders?
• Atypical anorexia nervosa (i.e. normal weight)
• Bulimia nervosa of low frequency or limited duration
• Binge-eating disorder of low frequency or limited duration
• Purging disorder
• Night eating syndrome
What are the unspecified eating disorders?
Other feeding and eating symptoms that cause clinically significant distress or impairment in social, occupational or other important areas of functioning, or having insufficient information to make a more specific diagnosis
Disordered Eating:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: -
- Restricted diet: ?
- Distorted body image: -
- Low weight: - 
- Binge-eating: ?
- Purging: ?
- Consumed by thoughts: -
- Restricted diet: ?
- Distorted body image: -
- Low weight: -
- Binge-eating: ?
- Purging: ?
Avoidant / Restrictive Eating Disorder:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +/-
- Restricted diet: +
* Distorted body image: -
- Low weight: +/- (or nutritional deficiency)
- Binge-eating: -
- Purging: -
- Consumed by thoughts: +/-
- Restricted diet: +
* Distorted body image: -
- Low weight: +/- (or nutritional deficiency)
- Binge-eating: -
- Purging: -
Anorexia Nervosa
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +
* Restricted diet: ++
* Distorted body image: ++
* Low weight: ++
- Binge-eating: +/- (depends on subtype)
- Purging: +/- (depends on subtype)
- Consumed by thoughts: +
* Restricted diet: ++
* Distorted body image: ++
* Low weight: ++
- Binge-eating: +/- (depends on subtype)
- Purging: +/- (depends on subtype)
Atypical Anorexia:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +
- Restricted diet: +
- Distorted body image: +
* Low weight: - (normal)
- Binge-eating: +/-
- Purging: +/-
- Consumed by thoughts: +
- Restricted diet: +
- Distorted body image: +
* Low weight: - (normal)
- Binge-eating: +/-
- Purging: +/-
Bulimia Nervosa:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +
- Restricted diet: +/-
- Distorted body image: +
- Low weight: - (normal or overweight)
* Binge-eating: +
* Purging: +
- Consumed by thoughts: +
- Restricted diet: +/-
- Distorted body image: +
- Low weight: - (normal or overweight)
* Binge-eating: +
* Purging: +
Binge-Eating Disorder:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +/-
- Restricted diet: +/-
- Distorted body image: +/-
- Low weight: - (normal or overweight)
* Binge-eating: +
- Purging: -
- Consumed by thoughts: +/-
- Restricted diet: +/-
- Distorted body image: +/-
- Low weight: - (normal or overweight)
* Binge-eating: +
- Purging: -
Purging Disorder:
- Consumed by thoughts?
- Restricted diet?
- Distorted body image?
- Low weight?
- Binge-eating?
- Purging?
- Consumed by thoughts: +/-
- Restricted diet: +/-
- Distorted body image: +/-
- Low weight: +/-
- Binge-eating: -
* Purging: +
- Consumed by thoughts: +/-
- Restricted diet: +/-
- Distorted body image: +/-
- Low weight: +/-
- Binge-eating: -
* Purging: +
What is the definition of obesity?
– Obesity: weighing >20% ideal body weight (IBW) or having a body mass index (BMI) of 30+
– Overweight: BMI 25-29.9
How common is obesity?
– > 1/3 of US adults are obese
– Increasingly children are overweight/obese
Significantly low weight is a criterion for which of the following?
a) Anorexia nervosa
b) Bulimia nervosa
c) Both
d) Neither
Anorexia Nervosa
Normal appetite occurs in which of the following eating disorders?
a) Anorexia nervosa
b) Bulimia nervosa
c) Both
d) Neither
Both
Purging behaviors may occur with which of the following eating disorders?
a) Anorexia nervosa
b) Bulimia nervosa
c) Both
d) Neither
Both