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92 Cards in this Set

  • Front
  • Back

neuroanatomy

an influence upon biopsychology


studies the structures of the NS

neurochemistry

an influence upon biopsychology


studies the chemical basis of neural activity

neuroendocrinology

an influence upon biopsychology


studies the interactions between the NS and the endocrine system

neuropathology

an influence upon biopsychology


studies NS disorders

Neuropharmacology

an influence upon biopsychology


studies the effects of drugs on neural activity

neurophysiology

an influence upon biopsychology


studies the functions and activities of the NS

The subdivisions of biopsychology: (6)

physiological psychology


psychopharmacology


neuropsychology


psychophysiology


cognitive neuroscience


comparative psychology and ethology

psychological psychology

a subdivision of biopsychology


dabbles in the surgical and electric brain manipulation of lab animals

psychopharmacology

a subdivision of biopsychology


drug manipulation of lab animals

neuropsychology

a subdivision of biopsychology


studies the effects of brain damage

psychophysiology

a subdivision of biopsychology


utilizes non invasive physical measurements (like pupil dilation)

cognitive neuroscience

a subdivision of biopsychology


studies the neural basis of cognition by using non invasive recording of brain activity

comparative psychology and ethology

a subdivision of biopsychology


studies the evolution/genetics/adaptiveness of behaviour, mostly using comparative methods

nerve types (based on direction)

Afferent nerves


Efferent nerves

Afferent nerves

go from the PNS to the CNS and carries sensory information

Efferent nerves

go from the CNS to the PNS and carries motor information

ganglia

clusters of nerve cells (in the PNS)


Efferent nerves synapse here


Two types - Sympathetic and Parasympathetic Ganglia

sympathetic ganglia (where are they)

in the PNS near the spinal cord

where are parasympathetic ganglia

in the PNS near target organ

where do sympathetic nerves originate

from the thoracic or lumbar regions of the CNS (chest/below chest respectively)

where do parasympathetic nerves originate

fromt eh brain (cranial nerves) or the sacral region (lower back) of the CNS

sympathetic nerves are used for (arousal/relaxation)

arousal

parasympathetic nerves are used for (arousal/relaxation)

relaxation

cranial nerves in order: (12)

olfactory


optic


occulomotor


troclear


trigeminal


abducens


facial


acoustic


glossopharyngeal


vagus


spinal accessory


hypoglossal

are cranial nerves sympathetic or parasympathetic

parasympathetic

glial cells - general info

they outnumber, support, nourish, and functionally interact with neurons

glial cell types in the PNS

satellite cells


schwann cells

satellite cells

support neurons within ganglia


in the PNS

schwann cells

a type of satellite cell


guides myelinization


in the PNS

glial cell types in the CNS

ogliodendrocytes


astrocytes/astroglia


microglia

ogliodendrocytes

glial cell in the CNS


myelinate axons by wrapping around them

astrocytes/astroglia

glial cell in the CNS


big cells which connect neurons to blood vessels and nourish them this way

microglia

glial cell in the CNS


triggered by injury


immune response, act as phagocytes

unipolar neurons

have only 1 protrusion from the cell body

bipolar neurons

have 2 protrusions from the cell body

multipolar neurons

have multiple protrusions from the cell body (this can include dendrites)

interneurons

have tiny or no axons

cortical neurons

can be divided into two types: pyrimidal cells and stellate cells

pyrimidal cells

a type of cortical neuron


multipolar neuron with pyramid shaped bodies


have one big apical dendrite and a really long axon

stellate cells

a type of cortical neuron


small star shaped interneurons with really small axons

protection of the CNS takes place through 4 mechanisms:

bones


meninges


CSF


blood brain barrier

how do bones contribute to the protection of the CNS

the skull and vertebrae offer physical protection

define the meninges and how they contribute to the protection of the CNS

composed of 3 layers (dura mater, arachnoid layer, pia mater)


offers physical protection

how does CSF contribute to the protection of the CNS

acts like a cushion!


produced by blood vessels on the pia mater (called the choroid plexus)


drain into the jugular veins constantly


resides in the cavities of the CNS

when does hydracephalus occur

when the CSF is prevented from draining

name 5 ways to visualize the NS

golgi stain


nissl stain


myelin stain


electron microscopy


neuroanatomical tracing

golgi stain

neurons and golgi cells turn black


silver nitrate compound


not very precise

Nissl stain

cell bodies turn purple

myelin stain

myelinated fibers to turn black

neuroanatomical tracing

put in a fluorescent dye and track where it goes


can be traced anterograde (from cell body to innervated area) or retrograde

myencephalon (what part of brain, composed of, responsible)

bottom most part of brain (hindbrain)


aka medulla oblongata, situated just above spinal cord


includes the reticular formation and a bunch of tracts


main fntns include sleeping/arousal (cells here are active when you're awake), attention, movement, muscle tone,

--

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the physical changes that occur with memory

LTP, changes in synaptic efficiency

two overall types of memory

explicit


implicit

types of explicit memory

semantic


episodic

in temporally limited amnesia, what kind of memory is somewhat spared?

semantic

are episodic memories episodic forever?

no, they can become semantic memories (and therefore independent of the hippocampus) as time passes and they are stripped of context

what happened to HM and why

he had a bilateral medial temporal lobectomy done to stop his seizures (which was successful)


However, not just the hippocampus (the target) was removed. Due to sloppy surgical techniques much of the tissue covering the subcortical structure was also taken out and so there was massive amnesia (BOTH retro and anterograde) (other important tissues that were affected were the entorhinal, perirhinal, and parahippocampal cortexes)

digit span test

for HM


verbally reciting lists of numbers from memory


performed badly compared to controls

block tapping memory span test

for HM


non verbal (sensorimotor) but otherwise is like the digit span test


had to repeat a sequence of blocks


performed badly compared to controls (his limit was 5, he could never get to 6)

mirror drawing test

for HM


sensorimotor


showed improvement which is consistent with the idea of HMs implicit memory being spared

rotary pursuit test

for HM


sensorimotor


involves keeping a stylus on a target atop of a moving wheel


HM improved over a number of trials but never had any memory of the previous trials

incomplete picture task

for HM


priming


he could do this, but it's implicit so it's kind of expected



classical conditioning

HM could do this


implicit memory so this is kind of expected, to be quite honest

neuromuscular junction

the synapse between a motor neuron and a muscle fibre.


cholinergic

adrenergic receptors

receptrors that are targeted by epinephrine and norepinephrine

antidromic condition

an action potential going backwards up the axon


impossible under natural conditions

standard consolidation theory vs multiple trace theory and memory time spent in the hippocampus

standard thinks it's only there for a little bit whereas multiple trace thinks memories are in the hippocampus permanently

stages (5) of prenatal development of the CNS

induction of the neural plate


neural proliferation


migration and Aggregation


axon growth and synapse formation


neuron death and synapse rearrangement



evolution of the neural plate

folds and becomes the neural groove


continues/finishes folding and becomes the neural tube (this folding action also forms the central canal and the neural crest)

out of the following structures, which will form the PNS and which will form the CNS?


Neural tube


Neural crest

Neural crest will become PNS

where does the most neural proliferation occur

around the central canal, in the neural tube. this is called the ventricular zone

when do cells complete differentiation

after the migration stage

which methods to cells use to migrate

glial mediated locomotion (wherein radial glial cells give a scaffold for the cells to crawl along)




Somal translocation (an extension of the cell extends and retracts, pulling it through the 3environment and following chemical guidance signals)

how do glial cells move (radially, tangentially, or both?)

only radially

how do neurons move (radially, tangentially, or both?)

can move both ways

what does the process of aggregation entail

groups of cells coming together (at their newly migrated-to locations) and becoming organized into the structure they are going to become

what kind of molecule helps the process of aggregation

CAMs (cell adhesion molecules)




These are present on the surfaces of neuron and glial cells and aid in migration to, recognition of and adhesion to other cells

what in the hell is a growth cone

it's a thing on a growing axon that sniffs around the environment looking for signals

any weird structures on growth cones?

yeah there are these little fingerlike things called filopedia which extend and retract and shizz

what the hell is the chemoaffinity hypothesis

thinks that each target area has a specific label and the growth cones like following in the paths of other growth cones that came before them

what the hell is the topographical gradient hypothesis

thinks that the way that growth cones find their way around is that they look for ratios of chemicals

glial cells and synaptogenesis

astrocytes promote it

neurotrophins and cell death

apoptosis occurs when neurotrophins are absent

permissive experiences

NEEDED for correct development

instructive experiences

may offer some benefit but aren't NECESSARY

critical periods

you need to get specific input in this time frame in order to develop properly

sensitive periods

when specific stimuli have a greater effect

3 autism symptoms for diagnosis

reduced capability for understanding/interpreting the emotions of others




reduced social interaction and communication




preoccupation with a single subject or activity

4 phases of autistic brain growth

slight prenatal undergrowth




WOAH SLOW DOWN OVERGROWTH (from 6-14) months




growth rate slows from 1-5 years old




gradual decline in brain size until about adolescence when it is normally sized

williams syndrome

great social skills but emotionally immature and have severe mental retardation (particularly have spatial deficits)(due to small occipital and parietal lobes)




have a genetic mutation for the "elastin" gene

Kallmann syndrome

abnormal genitals and sense of smell


neuronal migration disorder


failed migration of the cells that code for odors and those that secrete sex hormones