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28 Cards in this Set

  • Front
  • Back

Membrane Potential

Difference in electrical charge between inside and outside of a cell

Resting potential

Difference in internal charge compared to extracellular environment.

Neuron Resting Charge / Resting Membrane Potential

-70mV

Anions

Negative charged ions

Cations

Positive charged ions

Polarized

Neuron at rest, the charge is opposite to the outside.

Depolarizing

Neuron in the process of firing, becoming similar to the outside

Hyperpolarize

Neuron internal charge big opposite from the outside

Electrostatic Pressure

Pull between NA+ intra and extra-cellular.

Factors that influence distribution of NA+ and K+

1. Electrostatic Pressure


2. Random Motion


3. Concentration Gradient

Concentration Gradient

Random motion and lack of NA+ inside the cell

Sodium-Potassium Pump

Regulates frequency at which ions can enter/exit without changing the internal charge

Neural Conduction

Process of changing internal charge so neuron can fire

Chemical Messengers

Neurotransmitters, hormones or other chemicals received by dendrites

EPSP

Excitatory Postsynaptic Potential. Depolarizations that increase likelihood neuron will fire.

IPSP

Inhibitory Postsynaptic Potentials. Hyperpolarizations that decrease likelihood neuron will fire.

Graded Responses

Amplitudes of EPSPs & IPSPs proportional to intensity of signals that illicit them.

What does a strong or weak signal mean in terms of PSPs?

Weak Signal = Small PSP


Strong Signal = Large PSP

Threshold of Excitation

-65mV

Peak Membrane Potential

+50mV

Rising Phase

Depolarization of cell, approaching 0mV and above 0mV

Peak Phase

NA channels close, K channels open

Falling Phase

Repolarization, loss of K

Refractory Period

Hyperpolarized, difficult to reactivate and fire

Resting Potential

State of neuron returned to over time and ready to be fired again

Propogation

Electrical signal is transmitted down the axon. Occurs after EPSPs have generated threshold of excitation

Action Potential Properties

Non-graded and non-decremental

Saltatory Conduction

Propagates AP through axons. Recharges AP to keep non-decremental / non-graded. Depolarized the neuron