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11 Cards in this Set

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Collagen

structural protein; has a trihelical fiber (three left-handed helices) and makes up most of the extracellular matrix of connective tissue; found throughout the body and is important in providing strength and flexibility

Elastin

structural protein; component of the extracellular matrix of connective tissue; role is to stretch and then recoil like a spring

Keratins

structural protein; intermediate filament proteins found in epithelial cells; contribute to mechanical integriy of the cell; also function as a regulatory protein; primary protein in hair and nails

Actin

structural protein; makes up microfilaments and the thin filaments in myofibrils; the most abundant protein in eukaryotic cells; contain a + and - side that allows motor proteins to travel unidirectionally along an actin filament

Tubulin

structural protein; protein that makes up microtubules (important for chromosome separation in mitosis and meiosis [centrioles] and intracellular transport-with kinesin and dynein);

Myosin

motor protein; primary motor that interacts with actin- thick filament in a myofibril; can also be involved in cellular transport

Kinesin

motor protein; associated with microtubules; have two heads, with one remaining on tubulin at all times; moves towards positive end of microtubule; play a key role in aligning chromosomes during metaphase and depolymerizing microtubules during ana phase of mitosis; vesicle transport

Dynein

motor protein; associated with microtubules- moves towards negative end; involved in the sliding movement of cilia and flagella; important for vesicle transport

Cadherin

cell adhesion molecule (CAM); mediates calcium-dependent cell-adhesion; often hold similar cell types together

Integrins

Cell adhesion molecule (CAM); all have two membrane spanning chains called alpha and beta; important in binding to and communicating with the extracellular matrix; role in cellular signaling and can promote cell division, apoptosis, and other processes

Selectins

cell adhesion molecule (CAM); bind to carbohydrate molecules that project from other cell surfaces; these are the weakest bonds and are expressed on white blood calls and the endothelial cells that line blood vessels