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23 Cards in this Set
- Front
- Back
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Chloramphenicol
Macrolide Lincosamide Streptogramin Oxazolidinone |
50S
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Bacteriostatic
Broad Spectrum Reversible 50S Inhibit Peptidyl Transferase |
Chloramphenicol
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Bone Marrow Suppression
Anemia/Leukopenia/Thrombocytopenia Idiosyncratic Response Blood Dyscrasis Aplastic Anemia |
Chloramphenicol
Hematological Toxicity |
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Gray (Baby) Syndrome
Lack Glucuronyl Transferase |
Chloramphenicol
Adverse |
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Erythromycin
Clarithromycin Azithromycin |
Macrolide
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Substitute for Penicillin
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Macrolide
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Enhance Gram (-) Activity
Campylobacter jejuni Helicobacter pylori Shigella sp |
Azithromycin/Clarithromycin
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Child/Pregnant Female
Allergy to Penicillin Outpatient CAP |
Macrolide
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Mycoplasma pneumoniae
Chlamydia Bordetella protussis Campylobacter |
Macrolide
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Bacteriostatic
Reversible 50S Inhibit Peptide Chain Elongation Inhibit Translocation of Peptide tRNA (A to P Site) |
Macrolide
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Inhibit CYP3A4
GI (Direct Stimulate GI Motile) Cholestatic Hepatitis |
Macrolide
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Anaerobe
Staphylococcus Streptococcus |
Clindamycin
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Bacteriostatic
50S Inhibit Transpeptidase |
Clindamycin
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Does Not Cross BBB
Penetrate Bone Transport into PolyMorphoNuclear Leukocyte/Macrophage (Abscess) |
Clindamycin
Pharmacokinetic |
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Severe Diarrhea
PSEUDOMEMBRANOUS COLITIS |
Clindamycin
Adverse |
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Gram (+)
MRSA QRSA VRSA PRSP VRE (faecium NOT faecalis) (DOC) |
Streptogramin
(Quinupristin/Dalfopristin) |
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Potent Inhibit CYP3A4
Arthralgia/Myalgia |
Streptogramin
(Quinupristin/Dalfopristin) |
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Linezolid
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Oxazolidinine
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VRE (faecium AND faecalis) (DOC)
MRSA (DOC) MSSA PRSP (DOC) |
Linezolid
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MonoAmine Oxidase Inhibitor
Myelosuppression |
Linezolid
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Gram (+)
Enterococcus faecium/faecalis (VRE) Staphylococcus aureus (MRSA) |
Daptomycin
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Depolarization
Loss Membrane Potential Bactericidal Concentration Dependent |
Daptomycin
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NO Pneumonia
Bind Surfactant |
Daptomycin
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