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13 Cards in this Set

  • Front
  • Back

Vascular Smooth muscle tone, bronchiolar tone

Increase: TXA2, PGF2ɑ




Decrease: PGI2, PGE2, PGE1

Platelet aggregation/Activation

Increase: TXA2




Decrease: PGI2

Ductus Arteriosus Patency

Increase: most PGs, PGE1 used clinically

Gastric mucous production

Increased: PGE1, PGE2

Gastric acid secretion

Decreased: PGE1 and PGE2

Peripheral sensitisation to pain and proinflammation

Increased: PGE2 and PG12

Uterine contractions

Increased: PGE2, PGF2alpha

GI smooth muscle contraction

increased: Most PGs


Decreased: One subtype of PGE receptor

Bronchiolar tone:

Increased: PGF2alpha, TXA2, (one subtype of PG3 receptor)




Decreased: PGI2 (but irritant therefore no inhaler), PGE1 and PGE2

Pulmonary Vasoconstriction

PGF2alpha - therefore no IV use

Fever

PGE1/2

Wakefulness

PGD2

Renal vasodilation


PGE1/2, PGI2, PGD2