Principles Of Wound Healing/tissue Repair

Front 1

angiogenesis

Back 1

Formation of new blood vessels. the process by which a wound is vascularized in order to bring nutrients to the healing area & remove debris. These new vessels are considered "leaky" & are usually temporary.

Front 2

cicatrix

Back 2

A scar left by the formation of new connective tissue over a healing sore or wound

Front 3

collagen

Back 3

Produced by fibroblasts,
The fibrous protein constituent of bone, cartilage, tendon, & other connective tissue. It is converted into gelatin by boiling

Front 4

debridement

Back 4

Surgical excision of dead, devitalized, or contaminated tissue & removal of foreign matter from a wound

Front 5

fibronectin

Back 5

A type of large glycoprotein that is found on the surface of cells & mediates cellular adhesion, control of cell shape, & cell migration

Front 6

granulation tissue

Back 6

Small, fleshy, beadlike protuberances, consisting of outgrowths of new capillaries, on the surface of a wound that is healing

Front 7

keloid

Back 7

A red, raised formation of fibrous scar tissue caused by excessive tissue repair in response to trauma or surgical incision

Front 8

organization

Back 8

Functional impairment of tissue involved in wound healing

Front 9

proud flesh

Back 9

The swollen flesh that surrounds a healing wound, caused by excessive granulation

Front 10

resolution

Back 10

The subsiding or termination of an abnormal condition, such as a fever or an inflammation

Front 11

wound contraction

Back 11

Phenomenon of secondary union in which myofibroblasts at the edges of the wound contract & significantly reduce the area of the wound that must be filled with granulation tissue & subsequent scar

Front 12

internal (primary) callus

Back 12

Reunites the edges of the bone fragments in areas that are well vascularized,
Immature woven bone develops from the peuripotential cells of the endosteum & the inner layer of the periosteum

Front 13

external (bridging) callus

Back 13

Stabilizes the fracture,
Fibrocartilagenous collar that is formed around the fractured edge of the bone which eventually fuses with a similar collar formed at the edge of other bone fragments

Front 14

periosteum

Back 14

The dense fibrous membrane covering the surface of bones except at the joints & serving as an attachment for muscles & tendons

Front 15

endosteum

Back 15

The thin layer of cells lining the medullary cavity of a bone

Front 16

cortical bone

Back 16

Dense & forms the surface of bone,
aka compact bone

Front 17

trabecular bone

Back 17

spongy & makes up the bulk of the interior of most bones, including the vertebrae,
Also known as cancellous bone

Front 18

haversian canal

Back 18

Any of the tiny, interconnecting, longitudinal channels in bone tissue through which blood vessels, nerve fibers, & lymphatics pass

Front 19

volkman canal

Back 19

Any of the various canals in bone that transmit blood vessels from the periosteum into the bone

Front 20

osteon

Back 20

Also called Haversian system,
Predominant structures found in some lamellar or compact bone

Front 21

osteoid

Back 21

Resembling bone,
The bone matrix, especially before calcification

Front 22

woven bone

Back 22

Bony tissue characteristic of the embryonic skeleton in which the collagen fibers of the matrix are arranged irregularly in the form of interlacing networks,
aka nonlamellar bone, reticulated bone,
**Always the result of a pathologic condition if present in an adult

Front 23

lamellar bone

Back 23

Any bone with a microscopic structure consisting of thin layers or plates

Front 24

wolff law

Back 24

The principle that every change in the form & the function of a bone or in the function of the bone alone, leads to changes in its internal architecture & in its external form

Front 25

pseudoarthrosis

Back 25

The formation of a false joint caused by the failure of the bones to fuse

Front 26

non-union

Back 26

The failure of a fractured bone to heal normally